208238-30-6

Basic information

• Product Name: 4-[5-Benzyloxycarbonyl-3-(2-methoxycarbonylethyl)-4-(methoxycarbonylmethyl)pyrrol-2-ylmethyl]-2,8-bis(2-methoxycarbonylethyl)-3,7-bis(methoxycarbonylmethyl)-9-(2-trimethylsilylethoxycarbonyl)-4,5-dihydrodipyrrin-1(10H)-thione
• Synonyms: 4-[5-Benzyloxycarbonyl-3-(2-methoxycarbonylethyl)-4-(methoxycarbonylmethyl)pyrrol-2-ylmethyl]-2,8-bis(2-methoxycarbonylethyl)-3,7-bis(methoxycarbonylmethyl)-9-(2-trimethylsilylethoxycarbonyl)-4,5-dihydrodipyrrin-1(10H)-thione
• CAS NO: 208238-30-6
• Molecular Weight: 1010.2
• Mol File: 208238-30-6.mol

Chemical Properties

• CAS DataBase Reference: 4-[5-Benzyloxycarbonyl-3-(2-methoxycarbonylethyl)-4-(methoxycarbonylmethyl)pyrrol-2-ylmethyl]-2,8-bis(2-methoxycarbonylethyl)-3,7-bis(methoxycarbonylmethyl)-9-(2-trimethylsilylethoxycarbonyl)-4,5-dihydrodipyrrin-1(10H)-thione(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[5-Benzyloxycarbonyl-3-(2-methoxycarbonylethyl)-4-(methoxycarbonylmethyl)pyrrol-2-ylmethyl]-2,8-bis(2-methoxycarbonylethyl)-3,7-bis(methoxycarbonylmethyl)-9-(2-trimethylsilylethoxycarbonyl)-4,5-dihydrodipyrrin-1(10H)-thione(208238-30-6)
• EPA Substance Registry System: 4-[5-Benzyloxycarbonyl-3-(2-methoxycarbonylethyl)-4-(methoxycarbonylmethyl)pyrrol-2-ylmethyl]-2,8-bis(2-methoxycarbonylethyl)-3,7-bis(methoxycarbonylmethyl)-9-(2-trimethylsilylethoxycarbonyl)-4,5-dihydrodipyrrin-1(10H)-thione(208238-30-6)

Safety Data

• Hazardous Substances Data: 208238-30-6(Hazardous Substances Data)

Upstream product

• 155435-03-3 4-[5-benzyloxycarbonyl-3-(2-methoxycarbonylethyl)-4-(methoxycarbonylmethyl)pyrrol-2-ylmethyl]-2,8-bis(2-methoxycarbonylethyl)-3,7-bis(methoxycarbonylmethyl)-9-(2,2,2-tribromoethoxycarbonyl)-4,5-dihydrodipyrrin-1(10H)-one 
• 155435-04-4 C₄₄H₅₁N₃O₁₇ 

Downstream Products

• 207981-98-4 4-[5-Benzyloxycarbonyl-3-(2-methoxycarbonylethyl)-4-(methoxycarbonylmethyl)pyrrol-2-ylmethyl]-2,8-bis(2-methoxycarbonylethyl)-3,7-bis(methoxycarbonylmethyl)-9-(2-trimethylsilylethoxycarbonyl)-4,5-dihydrodipyrrin 
• 1025942-69-1 15-Acetyl-4-[5-benzyloxycarbonyl-3-(2-methoxycarbonylethyl)-4-(methoxycarbonylmethyl)pyrrol-2-ylmethyl]-14-formyl-2,8,13-tris(2-methoxycarbonylethyl)-3,7,12-tris(methoxycarbonylmethyl)-1,4,5,10,15,17-hexahydrodipyrrin 
• 208238-31-7 4-[5-Benzyloxycarbonyl-3-(2-methoxycarbonylethyl)-4-(methoxycarbonylmethyl)pyrrol-2-ylmethyl]-2,8-bis(2-methoxycarbonylethyl)-3,7-bis(methoxycarbonylmethyl)-9-(2-trimethylsilylethoxycarbonyl)-1,4,5,10-tetrahydrodipyrrin 
• 208238-39-5 10-Acetyl-4-[5-benzyloxycarbonyl-3-(2-methoxycarbonylethyl)-4-(methoxycarbonylmethyl)pyrrol-2-ylmethyl]-2,8-bis(2-methoxycarbonylethyl)-3,7-bis(methoxycarbonylmethyl)-1,4,5,10-tetrahydrodipyrrin 
• 208238-32-8 C₄₄H₅₃N₃O₁₆ 
• 208238-41-9 4-[5-Benzyloxycarbonyl-3-(2-methoxycarbonylethyl)-4-(methoxycarbonylmethyl)pyrrol-2-ylmethyl]-10-formyl-2,8-bis(2-methoxycarbonylethyl)-3,7-bis(methoxycarbonylmethyl)-1,4,5,10-tetrahydrodipyrrin 
• 208238-33-9 4-[5-Benzyloxycarbonyl-3-(2-methoxycarbonylethyl)-4-(methoxycarbonylmethyl)pyrrol-2-ylmethyl]-2,8-bis(2-methoxycarbonylethyl)-3,7-bis(methoxycarbonylmethyl)-1,4,5,10-tetrahydrodipyrrin 

Relevant articles and documents

Biosynthesis of porphyrins and related macrocycles. Part 50. Synthesis of the N-formyl-dihydro analogue of the spiro-intermediate and its interaction with uroporphyrinogen III synthase

The proposed intermediacy of the spiro-system 1 for the biosynthesis of uroporphyrinogen III has focused attention on its synthesis. In this paper the approach that is explored is to carry a dihydropyrrole through the entire synthesis with the intention of converting it into a 2H-pyrrole (pyrrolenine) in one of the final steps. The chemistry of the different types of synthetic intermediates is described and also it is demonstrated that the N-formyl dihydropyrrole 37 is a strong inhibitor of cosynthetase. The conclusion is reached that of all the possible routes to the spiro-pyrrolenine 1, that via the protected dihydropyrrole 30 shows the greatest promise.