208238-39-5

Upstream product

• 108-24-7 acetic anhydride 
• 208238-33-9 4-[5-Benzyloxycarbonyl-3-(2-methoxycarbonylethyl)-4-(methoxycarbonylmethyl)pyrrol-2-ylmethyl]-2,8-bis(2-methoxycarbonylethyl)-3,7-bis(methoxycarbonylmethyl)-1,4,5,10-tetrahydrodipyrrin 
• 207981-95-1 4-[5-Benzyloxycarbonyl-3-(2-methoxycarbonylethyl)-4-(methoxycarbonylmethyl)pyrrol-2-ylmethyl]-2,8-bis(2-methoxycarbonylethyl)-3,7-bis(methoxycarbonylmethyl)-9-(2-trimethylsilylethoxycarbonyl)-4,5-dihydrodipyrrin-1(10H)-one 
• 208238-30-6 4-[5-Benzyloxycarbonyl-3-(2-methoxycarbonylethyl)-4-(methoxycarbonylmethyl)pyrrol-2-ylmethyl]-2,8-bis(2-methoxycarbonylethyl)-3,7-bis(methoxycarbonylmethyl)-9-(2-trimethylsilylethoxycarbonyl)-4,5-dihydrodipyrrin-1(10H)-thione 
• 207981-98-4 4-[5-Benzyloxycarbonyl-3-(2-methoxycarbonylethyl)-4-(methoxycarbonylmethyl)pyrrol-2-ylmethyl]-2,8-bis(2-methoxycarbonylethyl)-3,7-bis(methoxycarbonylmethyl)-9-(2-trimethylsilylethoxycarbonyl)-4,5-dihydrodipyrrin 
• 208238-31-7 4-[5-Benzyloxycarbonyl-3-(2-methoxycarbonylethyl)-4-(methoxycarbonylmethyl)pyrrol-2-ylmethyl]-2,8-bis(2-methoxycarbonylethyl)-3,7-bis(methoxycarbonylmethyl)-9-(2-trimethylsilylethoxycarbonyl)-1,4,5,10-tetrahydrodipyrrin 
• 208238-32-8 C₄₄H₅₃N₃O₁₆ 
• 155435-03-3 4-[5-benzyloxycarbonyl-3-(2-methoxycarbonylethyl)-4-(methoxycarbonylmethyl)pyrrol-2-ylmethyl]-2,8-bis(2-methoxycarbonylethyl)-3,7-bis(methoxycarbonylmethyl)-9-(2,2,2-tribromoethoxycarbonyl)-4,5-dihydrodipyrrin-1(10H)-one 
• 155435-04-4 C₄₄H₅₁N₃O₁₇ 

Downstream Products

• 1025942-69-1 15-Acetyl-4-[5-benzyloxycarbonyl-3-(2-methoxycarbonylethyl)-4-(methoxycarbonylmethyl)pyrrol-2-ylmethyl]-14-formyl-2,8,13-tris(2-methoxycarbonylethyl)-3,7,12-tris(methoxycarbonylmethyl)-1,4,5,10,15,17-hexahydrodipyrrin 

Relevant academic research and scientific papers

Biosynthesis of porphyrins and related macrocycles. Part 50. Synthesis of the N-formyl-dihydro analogue of the spiro-intermediate and its interaction with uroporphyrinogen III synthase

The proposed intermediacy of the spiro-system 1 for the biosynthesis of uroporphyrinogen III has focused attention on its synthesis. In this paper the approach that is explored is to carry a dihydropyrrole through the entire synthesis with the intention of converting it into a 2H-pyrrole (pyrrolenine) in one of the final steps. The chemistry of the different types of synthetic intermediates is described and also it is demonstrated that the N-formyl dihydropyrrole 37 is a strong inhibitor of cosynthetase. The conclusion is reached that of all the possible routes to the spiro-pyrrolenine 1, that via the protected dihydropyrrole 30 shows the greatest promise.