- Regioselectivity of the ring opening of propene oxides bearing electron-withdrawing substituents at the methyl group with Olah's reagent
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The regiochemistry of the hydrofluorination of terminal epoxides with Olah's reagent (Py·9HF) is dependent on the electron-withdrawing character of the β-substituents. Phenoxy ethers with different substitution patterns of the aromatic ring and several N-heterocycles were examined as β-substituents.
- Skupin, Rolf,Haufe, Guenter
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p. 157 - 165
(2007/10/03)
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- Synthesis and hypotensive activity of some succinimide derivatives
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A series of 1--2,5-pyrrolidinedione (3) has been prepared and tested for hypotensive activity on cats and dogs.The compound 3b showed better hypotensive activity. 1--2,5-pyrrolidinediones (6) and 1--2,5-pyrrolidinediones (9) have also been synthesised and tested for their hypotensive activity.Compounds 6b, 6e, 9b and 9e showed very mild hypotensive activity.While attempting the synthesis of 12 the unexpected 11 is obtained.
- Khadilkar, B M,Bhayade, S R
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p. 338 - 342
(2007/10/02)
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