209958-42-9

Basic information

• Product Name: N-Boc-4-Bromo-2-fluoroaniline
• Synonyms: (4-Bromo-2-fluorophenyl)carbamic acid tert-butyl ester;N-Boc-4-Bromo-2-fluoroaniline;tert-Butyl N-(4-bromo-2-fluorophenyl)carbamate;Carbamic acid, N-(4-bromo-2-fluorophenyl)-, 1,1-dimethylethyl ester
• CAS NO: 209958-42-9
• Molecular Formula: C₁₁H₁₃BrFNO₂
• Molecular Weight: 290.13
• Mol File: 209958-42-9.mol

Chemical Properties

• Boiling Point: 272.239°C at 760 mmHg
• Flash Point: 118.446°C
• Appearance: /
• Density: 1.459g/cm³
• Vapor Pressure: 0.006mmHg at 25°C
• Refractive Index: 1.555
• Storage Temp.: 2-8°C
• PKA: 11.90±0.70(Predicted)
• CAS DataBase Reference: N-Boc-4-Bromo-2-fluoroaniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-Boc-4-Bromo-2-fluoroaniline(209958-42-9)
• EPA Substance Registry System: N-Boc-4-Bromo-2-fluoroaniline(209958-42-9)

Safety Data

• Hazardous Substances Data: 209958-42-9(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
N-Boc-4-Bromo-2-fluoroaniline is utilized as a building block in organic synthesis for the creation of pharmaceuticals and other bioactive compounds. Its unique structure, featuring both bromine and fluorine atoms, enables the compound to participate in a wide range of chemical reactions, facilitating the synthesis of diverse organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, N-Boc-4-Bromo-2-fluoroaniline is employed as a key intermediate in the synthesis of various drugs. Its reactivity and the presence of the Boc group make it a valuable component in the development of new medications with specific therapeutic properties.
Used in Peptide Synthesis:
N-Boc-4-Bromo-2-fluoroaniline is used as a protective group in peptide synthesis. The Boc group helps prevent unwanted side reactions during the synthesis process, ensuring the formation of the desired peptide sequence with high purity and yield.
Used in Bioactive Compounds Synthesis:
N-Boc-4-Bromo-2-fluoroaniline is also used in the synthesis of bioactive compounds, where its reactivity and the presence of the Boc group contribute to the development of molecules with potential applications in various biological and medical fields.

InChI:InChI=1/C11H13BrFNO2/c1-11(2,3)16-10(15)14-9-5-4-7(12)6-8(9)13/h4-6H,1-3H3,(H,14,15)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 367-24-8 4-bromo-2-fluoroaniline 
• 75-09-2 dichloromethane 

Downstream Products

• 218301-89-4 2-fluoro-4-(1'-methylimidazol-2'-yl)-1-tert-butoxycarbonylaniline 
• 880252-35-7 [2-fluoro-4-(4-[1,2,3]triazol-1-yl-butyl)-phenyl]-carbamic acid tert-butyl ester 
• 870545-80-5 C₃₁H₃₃FN₄O₂ 
• 819058-34-9 2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline 
• 262444-42-8 tert-butyl N-[2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamate 
• 1293979-48-2 C₁₅H₁₉FN₂O₂ 
• 1293979-49-3 C₁₅H₂₁FN₂O₂ 
• 1293979-64-2 C₂₀H₂₈FN₃O₃ 
• 1293979-65-3 C₁₅H₂₀FN₃O 
• 1293979-59-5 C₂₄H₂₃ClFN₃O₃S 
• 1293979-58-4 C₂₄H₂₃ClFN₃O₃S 
• 1293979-57-3 C₂₀H₂₁ClFN₃O₃S₂ 
• 1293979-56-2 C₂₀H₂₁ClFN₃O₃S₂ 

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