210824-69-4

Basic information

• Product Name: 3-Bromo-4-methylbenzenesulphonamide
• Synonyms: 3-Bromo-4-methylbenzenesulphonamide;3-Bromo-4-methylbenzenesulfonamide;2-Bromo-4-sulphamoyltoluene, 2-Bromo-4-(aminosulphonyl)toluene;3-Bromo-4-methylbenzenesulphonamide 98%;3-Bromo-4-methylbenzenesulphonamide98%
• CAS NO: 210824-69-4
• Molecular Formula: C₇H₈BrNO₂S
• Molecular Weight: 235.08
• Product Categories: blocks;Bromides;Sulfonamides
• Mol File: 210824-69-4.mol

Chemical Properties

• Boiling Point: 379°Cat760mmHg
• Flash Point: 183°C
• Appearance: /
• Density: 1.658g/cm³
• Vapor Pressure: 6.05E-06mmHg at 25°C
• Refractive Index: 1.599
• Storage Temp.: 2-8°C
• PKA: 9.94±0.60(Predicted)
• CAS DataBase Reference: 3-Bromo-4-methylbenzenesulphonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromo-4-methylbenzenesulphonamide(210824-69-4)
• EPA Substance Registry System: 3-Bromo-4-methylbenzenesulphonamide(210824-69-4)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 210824-69-4(Hazardous Substances Data)

Usage

Uses

Used in Organic Chemistry:
3-Bromo-4-methylbenzenesulphonamide is used as a reagent for the synthesis of complex organic compounds. Its unique structure and functional groups make it a valuable intermediate in the preparation of various organic molecules.
Used in Pharmaceutical Industry:
3-Bromo-4-methylbenzenesulphonamide is used as a building block in the development of new pharmaceutical compounds. Its presence in the molecular structure can contribute to the desired biological activity and therapeutic effects of the final drug product.
Used in Research and Development:
3-Bromo-4-methylbenzenesulphonamide is used as a research compound in academic and industrial laboratories. It serves as a starting material for the exploration of new chemical reactions and the discovery of novel chemical entities with potential applications in various fields.

InChI:InChI=1/C7H8BrNO2S/c1-5-2-3-6(4-7(5)8)12(9,10)11/h2-4H,1H3,(H2,9,10,11)

Upstream product

• 7745-91-7 3-bromo-4-methylaniline 
• 70-55-3 toluene-4-sulfonamide 

Downstream Products

• 909187-69-5 4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide 
• 1261295-05-9 4-sulfamoyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzylacetate 
• 1261295-04-8 4-(bromomethyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide 

Relevant articles and documents

Phthalazine, aza- and diaza-phthalazine compounds and methods of use

The present invention comprises a new class of compounds useful for the prophylaxis and treatment of protein kinase mediated diseases, including inflammation and related conditions. The compounds have a general Formula I wherein A1, A2, B, R1, R2, R3 and R4 are defined herein. The invention also comprises pharmaceutical compositions including one or more compounds of Formula I, uses of such compounds and compositions for treatment of kinase mediated diseases including rheumatoid arthritis, psoriasis and other inflammation disorders, as well as intermediates and processes useful for the preparation of compounds of Formula I.

Five-membered heterocycles having biphenylsulfonyl substitution, with sulfonylcyanamide side chain, compositions containing them, and methods of using them

Five-membered heterocycles having biphenylsulfonyl substitution, process for their preparation, their use as a medicament or diagnostic, and medicament comprising them. Compounds of the formula I in which the symbols have the meanings indicated in the claims, have outstanding antiarrhythmic properties and exhibit a cardioprotective component. They can preventively inhibit or greatly decrease the pathophysiological processes in the formation of ischemically induced damage, in particular in the elicitation of ischemically induced cardiac arrhythmias. Moreover, they have a potent inhibitory action on the proliferation of cells.