210992-31-7

Basic information

• Product Name: 1-[1-(5-chloro-2-pyridinyl)-5-methyl-1H-pyrazol-4-yl]-1-ethanone
• Synonyms: 1-[1-(5-chloro-2-pyridinyl)-5-methyl-1H-pyrazol-4-yl]-1-ethanone
• CAS NO: 210992-31-7
• Molecular Formula: C₁₁H₁₀ClN₃O
• Molecular Weight: 235.6696
• Mol File: 210992-31-7.mol

Chemical Properties

• Melting Point: 138-140°
• Appearance: /
• CAS DataBase Reference: 1-[1-(5-chloro-2-pyridinyl)-5-methyl-1H-pyrazol-4-yl]-1-ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[1-(5-chloro-2-pyridinyl)-5-methyl-1H-pyrazol-4-yl]-1-ethanone(210992-31-7)
• EPA Substance Registry System: 1-[1-(5-chloro-2-pyridinyl)-5-methyl-1H-pyrazol-4-yl]-1-ethanone(210992-31-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 210992-31-7(Hazardous Substances Data)

Usage

Explanation

The molecular formula represents the number of atoms of each element present in a molecule of the compound.

Explanation

The compound belongs to a group of chemical compounds that contain a pyrazole ring.

Explanation

The compound is used as a starting material in the development of new drugs due to its potential to be modified and incorporated into various active molecules.

Explanation

The compound's unique structure and properties make it a candidate for further research and development in the pharmaceutical industry.

Explanation

Depending on the compound's properties and uses, it may interact with various biological systems, potentially leading to therapeutic or diagnostic applications.

Explanation

The compound's unique structure and properties make it a promising candidate for the development of new drugs to treat various diseases and disorders.

Explanation

The compound's interactions with biological systems may also make it useful in the development of diagnostic tools for detecting or monitoring the progression of diseases.

Class

Pyrazole derivatives

Pharmaceutical research

Building block for synthesis of biologically active molecules

Potential applications

Development of new drugs for treatment of diseases and disorders

Chemical structure

Pyrazole ring, chloro-substituted pyridine group, methyl group, and ethanone functional group

Effects on biological systems

Wide range of potential effects

Therapeutic applications

Potential for development of new drugs

Diagnostic applications

Potential for use in identifying or monitoring diseases

Upstream product

• 33884-41-2 ethoxylideneacetylacetone 
• 27032-63-9 5-chloro-pyridin-2-yl hydrazine 

Downstream Products

• 700344-71-4 1-[1-(5-chloro-pyridin-2-yl)-5-methyl-1H-pyrazol-4-yl]-3-[4-(3,5-difluoro-phenyl)-piperazin-1-yl]-propan-1-one 

Relevant articles and documents

Synthesis and antitumor activity of novel pyrimidinyl pyrazole derivatives. III. Synthesis and antitumor activity of 3-phenylpiperazinyl-1-trans-propenes

A series of novel 3-[4-phenyl-1-piperazinyl]-1-[5-methyl-1-(2-pyrimidinyl)- 4-pyrazolyl]-1-trans-propenes and related compounds were synthesized and evaluated by their cytotoxic activity against several tumor cell lines in vitro and in vivo antitumor acti

Pyrazole derivatives

The present invention relates to cis- and trans-forms of pyrazole derivatives, salts thereof, or agents containing the same, and represented by the general formula (I): wherein G represents a nitrogen containing saturated heterocyclic structure represented by the following formula: These compounds exhibit anti-tumor activity on 5-FU-resistant tumors and effects on P glycoprotein expressing, multiple-drug resistant tumors. An example of a pyrazole derivative which demonstrates 50% inhibition of tumor cell growth is 3-[4-(3-chloro-5-fluorophenyl)-1 piperazinyl]-1-[1-(3-chloro-2-pyridyl)-5-methyl-4-pyrazolyl)-1-trans-propene hydrochloride. Synthesis of the compounds represented by formula (I) can be prepared by any one of various routes such as a Mannich reaction, a Wittig reaction, reductive amination or substitution by allylation.