211311-65-8

Basic information

• Product Name: N-(2-(4-broMophenyl)propyl)propane-2-sulfonaMide
• Synonyms: N-(2-(4-broMophenyl)propyl)propane-2-sulfonaMide
• CAS NO: 211311-65-8
• Molecular Formula: C₁₂H₁₈BrNO₂S
• Molecular Weight: 320.24582
• Mol File: 211311-65-8.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: N-(2-(4-broMophenyl)propyl)propane-2-sulfonaMide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-(4-broMophenyl)propyl)propane-2-sulfonaMide(211311-65-8)
• EPA Substance Registry System: N-(2-(4-broMophenyl)propyl)propane-2-sulfonaMide(211311-65-8)

Safety Data

• Hazardous Substances Data: 211311-65-8(Hazardous Substances Data)

Upstream product

• 10147-37-2 Isopropylsulfonyl chloride 
• 256381-13-2 2-(4-bromophenyl)propan-1-amine 
• 16532-79-9 4-Bromophenylacetonitrile 
• 42186-06-1 2-(4-Bromophenyl)propionitrile 
• 211314-90-8 2-(4-Bromophenyl)propylamine hydrochloride 

Downstream Products

• 211311-95-4 LY 404187 
• 1057001-26-9 4-(4-(tert-butoxycarbonyl-{4'-(1-methyl-2-(propane-2-sulfonylamino)-ethyl)-biphenyl-4-yl}-amino)-butyl)-2-phenyl-4,5-dihydro-oxazole-4-carboxylic acid ethyl ester 
• 211311-74-9 N-2-(4-Cyclohexylphenyl)propyl 2-propanesulfonamide 
• 400629-11-0 6-[4-(1-methyl-2-{[(methylethyl)sulfonyl]amino}ethyl)phenyl]-3-hydrobenzothiazol-2-one 

Relevant articles and documents

(BIS)sulfonamide derivatives

The present invention provides (bis) sulfonamide derivatives of formula (I) useful for potentiating glutamate receptor function in a mammal and therefore, useful for treating a wide variety of conditions, such as psychiatric and neurological disorders.

Heterocyclic sulfonamide derivatives

The present invention provides certain heterocyclic sulfonamide derivatives of formula (I): useful for potentiating glutamate receptor function in a patient and therefore, useful for treating a wide variety of conditions, such as psychiatric and neurological disorders.

N-substituted sulfonamide derivatives

The present invention provides certain N-substituted sulfonamide derivatives useful for potentiating glutamate receptor function in a mammal and therefore, useful for treating a wide variety of conditions, such as psychiatric and neurological disorders.

Heterocyclyl sulphonamide derivatives

The present invention relates to the potentiation of glutamate receptor function using certain heterocyclyl sulphonamide derivatives. It also relates to novel heterocyclyl sulphonamide derivatives, to processes for their preparation and to pharmaceutical compositions containing them.

Sulphonamide derivatives

Glutamate receptor function in a mammal may be potentiated using an effective amount of a compound of formulaR1—L—NHSO2R2??Iin whichR1 represents an unsubstituted or substituted aromatic or heteroaromatic group;R2 represents (1-6C)alkyl, (3-6C)cycloalkyl, (1-6C)fluoroalkyl, (1-6C)chloroalkyl, (2-6C)alkenyl, (1-4C)alkoxy(1-4C)alkyl, phenyl which is unsubstituted or substituted by halogen, (1-4C)alkyl or (1-4C)alkoxy, or a group, of formula R3R4N in which R3 and R4 each independently represents (1-4C)alkyl or, together with the nitrogen atom to which they are attached form an azetidinyl, pyrrolidinyl, piperidinyl, morpholino, piperazinyl, hexahydroazepinyl or octahydroazocinyl group; andL represents a (2-4C)alkylene chain which is unsubstituted or substituted by one or two substituents selected independently from (1-6C)alkyl, aryl(1-6C)alkyl, (2-6C)alkenyl, aryl(2-6C)alkenyl and aryl, or by two substituents which, together with the carbon atom or carbon atoms to which they are attached form a (3-8C)carbocyclic ring;and pharmaceutically acceptable salts thereof.Also disclosed are compounds of formula I, processes for preparing them and pharmaceutical compositions containing them.