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GLYBURIDE RELATED COMPOUND B (25 MG) (METHYL-[[4-[2-[(5-CHLORO-2-METHOXYBENZOYL)-AMINO]ETHYL]PHENYL]SULFONYL]CARBAMATE) (AS) is an impurity found in the synthesis of Glyburide (G598350), a second-generation sulfonylurea with hypoglycemic activity. It plays a significant role in the pharmaceutical industry due to its association with Glyburide, an antidiabetic medication.

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  • methyl N-[4-[2-[(5-chloro-2-methoxy-benzoyl)amino]ethyl]phenyl]sulfonylcarbamate

    Cas No: 21165-77-5

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  • GLYBURIDE RELATED COMPOUND B (25 MG) (METHYL-[[4-[2-[(5-CHLORO-2-METHOXYBENZOYL)-AMINO]ETHYL]PHENYL]SULFONYL]CARBAMATE) (AS)

    Cas No: 21165-77-5

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  • GLYBURIDE RELATED COMPOUND B (25 MG) (METHYL-[[4-[2-[(5-CHLORO-2-METHOXYBENZOYL)-AMINO]ETHYL]PHENYL]SULFONYL]CARBAMATE) (AS)

    Cas No: 21165-77-5

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  • 21165-77-5 Structure
  • Basic information

    1. Product Name: GLYBURIDE RELATED COMPOUND B (25 MG) (METHYL-[[4-[2-[(5-CHLORO-2-METHOXYBENZOYL)-AMINO]ETHYL]PHENYL]SULFONYL]CARBAMATE) (AS)
    2. Synonyms: GLYBURIDE RELATED COMPOUND B (25 MG) (METHYL-[[4-[2-[(5-CHLORO-2-METHOXYBENZOYL)-AMINO]ETHYL]PHENYL]SULFONYL]CARBAMATE) (AS);[[4-[2-[(5-Chloro-2-methoxybenzoyl)amino]ethyl]phenyl]sulfonyl]carbamic acid methyl ester;[4-[2-(2-Methoxy-5-chlorobenzoylamino)ethyl]phenylsulfonyl]carbamic acid methyl ester;Carbamic acid, ((4-(2-((5-chloro-2-methoxybenzoyl)amino)ethyl)phenyl)sulfonyl)-, methyl ester;Einecs 244-254-2;Glyburide Related Compound B (25 mg) (methyl-[[4-[2-[(5-chloro-2-methoxybenzoyl)-amino]ethyl]phenyl]sulfonyl]carbamate) (AS);GlibenclaMide (Glyburide) IMpurity B;N-[[4-[2-[(5-Chloro-2-Methoxybenzoyl)aMino]ethyl]phenyl]sulfonyl]carbaMic Acid Methyl Ester
    3. CAS NO:21165-77-5
    4. Molecular Formula: C18H19ClN2O6S
    5. Molecular Weight: 426.8713
    6. EINECS: 244-254-2
    7. Product Categories: N/A
    8. Mol File: 21165-77-5.mol
  • Chemical Properties

    1. Melting Point: 189-191℃
    2. Boiling Point: °Cat760mmHg
    3. Flash Point: °C
    4. Appearance: /
    5. Density: 1.361g/cm3
    6. Refractive Index: 1.576
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: GLYBURIDE RELATED COMPOUND B (25 MG) (METHYL-[[4-[2-[(5-CHLORO-2-METHOXYBENZOYL)-AMINO]ETHYL]PHENYL]SULFONYL]CARBAMATE) (AS)(CAS DataBase Reference)
    10. NIST Chemistry Reference: GLYBURIDE RELATED COMPOUND B (25 MG) (METHYL-[[4-[2-[(5-CHLORO-2-METHOXYBENZOYL)-AMINO]ETHYL]PHENYL]SULFONYL]CARBAMATE) (AS)(21165-77-5)
    11. EPA Substance Registry System: GLYBURIDE RELATED COMPOUND B (25 MG) (METHYL-[[4-[2-[(5-CHLORO-2-METHOXYBENZOYL)-AMINO]ETHYL]PHENYL]SULFONYL]CARBAMATE) (AS)(21165-77-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 21165-77-5(Hazardous Substances Data)

21165-77-5 Usage

Uses

Used in Pharmaceutical Industry:
GLYBURIDE RELATED COMPOUND B (25 MG) (METHYL-[[4-[2-[(5-CHLORO-2-METHOXYBENZOYL)-AMINO]ETHYL]PHENYL]SULFONYL]CARBAMATE) (AS) is used as an impurity in the synthesis of Glyburide, which is an antidiabetic medication. Its presence is crucial for the development and production of Glyburide, a drug that helps manage blood sugar levels in patients with diabetes.
The compound is essential in the pharmaceutical industry as it contributes to the synthesis of Glyburide, a medication that has hypoglycemic properties. This makes it a valuable component in the development and production of antidiabetic drugs, ultimately aiding in the management of diabetes and improving the quality of life for patients with this condition.

Check Digit Verification of cas no

The CAS Registry Mumber 21165-77-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,1,6 and 5 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 21165-77:
(7*2)+(6*1)+(5*1)+(4*6)+(3*5)+(2*7)+(1*7)=85
85 % 10 = 5
So 21165-77-5 is a valid CAS Registry Number.
InChI:InChI=1/C18H19ClN2O6S/c1-26-16-8-5-13(19)11-15(16)17(22)20-10-9-12-3-6-14(7-4-12)28(24,25)21-18(23)27-2/h3-8,11H,9-10H2,1-2H3,(H,20,22)(H,21,23)

21165-77-5 Well-known Company Product Price

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  • Sigma-Aldrich

  • (Y0000242)  Glibenclamide impurity B  European Pharmacopoeia (EP) Reference Standard

  • 21165-77-5

  • Y0000242

  • 1,880.19CNY

  • Detail
  • USP

  • (1295527)  Glyburide Related Compound B  United States Pharmacopeia (USP) Reference Standard

  • 21165-77-5

  • 1295527-25MG

  • 13,501.80CNY

  • Detail

21165-77-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl N-[4-[2-[(5-chloro-2-methoxybenzoyl)amino]ethyl]phenyl]sulfonylcarbamate

1.2 Other means of identification

Product number -
Other names EINECS 244-254-2

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:21165-77-5 SDS

21165-77-5Upstream product

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