21288-73-3Relevant articles and documents
PHENYLMORPHOLINES AND ANALOGUES THEREOF
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Page/Page column 54-55, (2011/12/04)
Provided herein are compounds and prodrugs and methods of preparation of compounds and prodrugs that are capable of functioning as releasers and/or uptake inhibitors of one or more monoamine neurotransmitters, including dopamine, serotonin, and norepinephrine. Also provided are pharmaceutical compositions comprising one or more of these compounds or prodrugs, which may further comprise one or more additional therapeutic agents. Also provided are methods of treatment of various conditions that may be responsive to modification of monoamine neutrotransmitter levels, such as pre-obesity, obesity, addiction, and depression.
Facile, efficient, and catalyst-free electrophilic aminoalkoxylation of olefins: Scope and application
Zhou, Ling,Tan, Chong Kiat,Zhou, Jing,Yeung, Ying-Yeung
supporting information; experimental part, p. 10245 - 10247 (2010/09/07)
A new one-pot electrophilic aminoalkoxylation reaction using olefin, cyclic ether, amine, and N-bromosuccinimide has been developed. The olefinic substrates and the cyclic ether partners can be flexibly varied to produce a range of amino ether derivatives. This novel protocol has been applied in the facile and efficient synthesis of biologically active morpholine compounds.
An approach to enantioselective 5-endo halo-lactonization reactions
Garnier, Jean Marc,Robin, Sylvie,Rousseau, Gerard
, p. 3281 - 3291 (2008/02/10)
Enantioselective lactonization of 4-substituted but-3-enoic acids using iodobis(N-methylephedrine) hexafluoroantimonate in dichloromethane at low temperatures is reported. The presence of bis(N-methylephedrine)silver(I) hexafluoroantimonate, derived from
Means and method for aiding individuals to stop smoking
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, (2008/06/13)
Individuals are aided in their desire to stop tobacco smoking and lose overweight by administering internally a combination of pharmaceuticals comprising an imidazoline derivative, such as clonidine hydrochloride, with an anorectic, such as phentermine resin.