214143-79-0

Basic information

• Product Name: Pyrrolo[1,2-a]quinoxalin-4(5H)-one, 1,2,3,3a-tetrahydro-, (3aR)- (9CI)
• Synonyms: Pyrrolo[1,2-a]quinoxalin-4(5H)-one, 1,2,3,3a-tetrahydro-, (3aR)- (9CI);(3AR)-1,2,3,3A-TETRAHYDROPYRROLO[1,2-A]QUINOXALIN-4(5H)-ONE
• CAS NO: 214143-79-0
• Molecular Formula: C₁₁H₁₂N₂O
• Molecular Weight: 188.22578
• Product Categories: PIPERIDINE
• Mol File: 214143-79-0.mol

Chemical Properties

• Boiling Point: 386.9±31.0 °C(Predicted)
• Appearance: /
• Density: 1.28±0.1 g/cm3(Predicted)
• PKA: 13.80±0.20(Predicted)
• CAS DataBase Reference: Pyrrolo[1,2-a]quinoxalin-4(5H)-one, 1,2,3,3a-tetrahydro-, (3aR)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrrolo[1,2-a]quinoxalin-4(5H)-one, 1,2,3,3a-tetrahydro-, (3aR)- (9CI)(214143-79-0)
• EPA Substance Registry System: Pyrrolo[1,2-a]quinoxalin-4(5H)-one, 1,2,3,3a-tetrahydro-, (3aR)- (9CI)(214143-79-0)

Safety Data

• Hazardous Substances Data: 214143-79-0(Hazardous Substances Data)

Usage

Uses

Used in Medicinal Chemistry:
Pyrrolo[1,2-a]quinoxalin-4(5H)-one, 1,2,3,3a-tetrahydro-, (3aR)(9CI) is utilized as a compound of interest in medicinal chemistry for its structural features that may contribute to its biological activity. The exploration of its properties could lead to the development of new pharmaceutical agents.
Used in Drug Discovery:
In the field of drug discovery, Pyrrolo[1,2-a]quinoxalin-4(5H)-one, 1,2,3,3a-tetrahydro-, (3aR)(9CI) serves as a candidate molecule for further research and investigation. Its unique stereochemistry and heterocyclic system may offer insights into its pharmaceutical relevance and potential therapeutic uses, warranting additional studies to uncover its full potential.

Upstream product

• 214143-72-3 (R)-N-(2-nitrophenyl)proline 

Downstream Products

• 214353-20-5 (3AR)-1,2,3,3a,4,5-hexahydro-pyrrolo[1,2-a]quinoxaline 

Relevant articles and documents

Biphenyl derivatives and drug composition

A biphenyl derivative represented by the following general formula (1) and a pharmaceutically acceptable salt thereof: [In the formula (1), A represents a single bond, —CH2—, —CO—, —CS— or —SO2—; B represents a single bond or —CH2—; R1represents a hydrogen atom, —OH, —NR11R12(wherein R11and R12each independently represents a hydrogen atom or an alkyl group having 1 to 4 carbon atoms), —OCOCH3, or a halogen atom; R2represents a hydrogen atom or R1and R2form a group ═O together; R3represents a hydrogen atom or an alkyl group having 1 to 4 carbon atoms; provided that in the formula, the absolute configuration of the position a may be either R or S]. The compound of the present invention has considerably high safety and efficacy and is useful as, in particular, a vasopressin receptor antagonist.