- Synthesis method of 2,3,4-trihydroxyl benzaldehyde
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The invention provides a synthesis method of 2,3,4-trihydroxyl benzaldehyde, which is characterized in that pyrogallol is used as an initial raw material, and the synthesis of 2,3,4-trihydroxyl benzaldehyde comprises three steps of phenolic hydroxyl protection, formylation and de-protection. The method has the advantages of cheap and easily available raw materials, simple operation, high product yield and purity, and small amount of three wastes, and has excellent economic and environmental benefits.
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- Dienaminodiones, new push-pull alkenes, from 3,4-dihydroxysalicylaldehyde-derived Schiff base
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An atom-economical one-pot synthesis of a new push-pull dienaminodiones from a 3,4-dihydroxysalicylaldehyde-derived Schiff base and indoles in the presence of phenyliodine(III) diacetate is described. Variation of indoles and anilines constitute a broad substrate scope of the methodology with good to moderate yields. Formation of Schiff base followed by an indole addition to afford dienaminodione takes place in one-pot; thus, the present method serves as a sequential multicomponent reaction. The present work also serves as a methodology to afford indole variants of natural product talaroenamine B.
- Ravindran, Jaice,Ingaladal, Nagaraja,Lankalapalli, Ravi S.
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- Benzyl and benzaldehyde-derived metabolites from desert actinomycetes Sp. CDS
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Chromatographic purification of the culture broth of Actinomycetes CDS1 provided five new (1-5) and three known (6-8) metabolites. The new compounds 1, 4 and 5 were elucidated due to 1D-, 2D-NMR techniques, FABMS and HR-FABMS analyses. The nature of glycosidic part in 4 was confirmed through optical rotation value and comparison of the Rf value of hydrolyzed sugar with that of standard sample. Compounds 2 and 3 were tentatively identified due to 1H NMR and +ve FAB-MS analysis as mixture in one of the polar minor fractions. Structures of the known compounds 6-8 were determined due to 1H NMR and FABMS analysis.
- Nazir, Mamona,Mustafa, Rizwana,Tousif, Muhammad Imran,Ahmad, Shabir,Khatoon, Tasneem,Ahmad, Ishtiaq
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p. 919 - 923
(2018/10/02)
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