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6-Benzyl-3-nitro-5,6,7,8-tetrahydro-1,6-naphthyridine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 214699-24-8 Structure
  • Basic information

    1. Product Name: 6-Benzyl-3-nitro-5,6,7,8-tetrahydro-1,6-naphthyridine
    2. Synonyms: 6-Benzyl-3-nitro-5,6,7,8-tetrahydro-1,6-naphthyridine;1,6-Naphthyridine, 5,6,7,8-tetrahydro-3-nitro-6-(phenylmethyl)-
    3. CAS NO:214699-24-8
    4. Molecular Formula: C15H15N3O2
    5. Molecular Weight: 269.2985
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 214699-24-8.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 6-Benzyl-3-nitro-5,6,7,8-tetrahydro-1,6-naphthyridine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 6-Benzyl-3-nitro-5,6,7,8-tetrahydro-1,6-naphthyridine(214699-24-8)
    11. EPA Substance Registry System: 6-Benzyl-3-nitro-5,6,7,8-tetrahydro-1,6-naphthyridine(214699-24-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 214699-24-8(Hazardous Substances Data)

214699-24-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 214699-24-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,4,6,9 and 9 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 214699-24:
(8*2)+(7*1)+(6*4)+(5*6)+(4*9)+(3*9)+(2*2)+(1*4)=148
148 % 10 = 8
So 214699-24-8 is a valid CAS Registry Number.

214699-24-8Downstream Products

214699-24-8Relevant articles and documents

An expeditious synthesis of 3-(difluoromethoxy)- and 3-(trifluoromethoxy)-5,6,7,8-tetrahydro-1,6-naphthyridines

Guiadeen, Deodialsingh,Kothandaraman, Shankaran,Yang, Lihu,Mills, Sander G.,MacCoss, Malcolm

body text, p. 6368 - 6370 (2009/04/07)

An expeditious and concise synthesis of 3-(difluoromethoxy)-5,6,7,8-tetrahydro-1,6-naphthyridine and 3-(trifluoromethoxy)-5,6,7,8-tetrahydro-1,6-naphthyridines is described. Starting from N-benzyl piperidone, the key intermediates leading to these two bio

Design, synthesis, and evaluation of fused heterocyclic analogs of SCH 58261 as adenosine A2A receptor antagonists

Shah, Unmesh,Lankin, Claire M.,Boyle, Craig D.,Chackalamannil, Samuel,Greenlee, William J.,Neustadt, Bernard R.,Cohen-Williams, Mary E.,Higgins, Guy A.,Ng, Kwokei,Varty, Geoffrey B.,Zhang, Hongtao,Lachowicz, Jean E.

scheme or table, p. 4204 - 4209 (2009/04/10)

SCH 58261 is a reported adenosine A2A receptor antagonist which is active in rat in vivo models of Parkinson's Disease upon ip administration. However, it has poor selectivity versus the A1 receptor and does not demonstrate oral activity. Quinoline analogs have improved upon the selectivity and pharmacokinetics of SCH 58261, but were difficult to handle due to poor aqueous solubility. We report the design and synthesis of fused heterocyclic analogs of SCH 58261 with aqueous solubility as well as improved A2A receptor binding selectivity and pharmacokinetic properties. In particular, the tetrahydronaphthyridine 4s has excellent A2A receptor in vitro binding affinity and selectivity, is active orally in a rat in vivo model of Parkinson's Disease, and has aqueous solubility of 100 μM at physiological pH.

A facile synthesis of the 3-amino-5,6,7,8-tetrahydro[1,6]naphthyridine system and some alkylated and polycyclic homologues

Harling,Harrington,Thompson

, p. 787 - 797 (2007/10/03)

A facile, two step synthesis of the 3-amino-5,6,7,8-tetrahydro[1,6]naphthyridine system 1 and its more substituted homologues 2-5 via the condensation of mono- and bicyclic-4-piperidinones 11a-c, 12-14 with 3,5-dinitro-1-methyl-2-pyridone 6 in the presenc

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