14150-94-8

Usage

Uses

Used in Chemical Research:
1-Methyl-3,5-dinitro-1H-pyridin-2-one is used as a research compound for exploring its chemical properties and potential applications in various chemical reactions and processes. Its unique structure and reactivity make it a valuable subject for study in the field of chemistry.
Used in Pharmaceutical Development:
1-Methyl-3,5-dinitro-1H-pyridin-2-one is used as a starting material or intermediate in the synthesis of pharmaceutical compounds. Its chemical structure may be modified to create new drugs with potential therapeutic applications, making it an important component in the development of novel medications.
Used in Material Science:
1-Methyl-3,5-dinitro-1H-pyridin-2-one is used as a component in the development of new materials with specific properties, such as improved stability, reactivity, or other characteristics. Its incorporation into various materials can lead to advancements in material science and technology.
Used in Environmental Applications:
1-Methyl-3,5-dinitro-1H-pyridin-2-one is used as a chemical agent in environmental remediation processes, such as the treatment of contaminated water or soil. Its properties may allow it to interact with pollutants, facilitating their removal or neutralization, and contributing to environmental protection efforts.

InChI:InChI=1/C6H5N3O5/c1-7-3-4(8(11)12)2-5(6(7)10)9(13)14/h2-3H,1H3

Upstream product

• 32896-91-6 1-methyl-3-nitropyridin-2(1H)-one 
• 32896-90-5 1-methyl-5-nitro-2(1H)-pyridone 
• 2980-33-8 2-hydroxy-3,5-dinitropyridine 
• 694-85-9 1-methyl-2-pyridone 
• 2459-07-6 methyl pyridine-2-carboxylate 
• 77-78-1 dimethyl sulfate 
• 3719-45-7 1-methyl-6-oxo-1,6-dihydro-pyridine-3-carboxylic acid 
• 7697-37-2 nitric acid 
• 412035-58-6 1-methyl-5-nitro-6-oxo-1,6-dihydro-pyridine-3-carboxylic acid 
• 5418-51-9 5-nitro-2-hydroxypyridine 
• 6332-56-5 2-hydroxy-3-nitropyridine 
• 74-88-4 methyl iodide 
• 37943-43-4 1-methylpyridinium monomethyl sulfuric acid salt 
• 110-86-1 pyridine 

Downstream Products

• 1450-76-6 1-(2-hydroxy-5-nitrophenyl)ethanone 
• 72078-94-5 2-Aethoxalyl-4-nitrophenol 
• 10220-22-1 1-(4-nitro-phenyl)-pyrrolidine 
• 2423-71-4 2,6-dimethyl-4-nitro phenol 
• 67828-58-4 2-methyl-4-nitro-1-(1-pyrrolidinyl)benzene 
• 10389-51-2 1-morpholino-4-nitrobenzene 
• 84531-36-2 6,7-dihydro-3-nitro-5H-cyclopentapyridine 
• 72078-82-1 N-methylnitroacetamide 
• 84531-35-1 5,6,7,8-tetrahydro-3-nitro-quinoline 
• 131941-21-4 2-isopropyl-5-nitropyridine 
• 131941-24-7 5-nitro-2,3-diphenylpyridine 
• 131941-22-5 3-methyl-5-nitro-2-phenylpyridine 
• 131941-27-0 4-(5-nitropyridine-2-yl)benzonitrile 
• 42348-40-3 ethyl 5-nitrosalicylate 

Relevant academic research and scientific papers

NITRATION OF AROMATIC HETEROCYCLES WITH PALLADIUM(II) ACETATE AND SODIUM NITRITE.

Treatments of 1,3-dimethyluracil, 1-methyl-2-pyridone, and thiophene with palladium(II) acetate and sodium nitrite gave the corresponding nitro-substituted products.

DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS

The invention provides dihydroisoquinoline-2(1H)-carboxamide and related compounds, pharmaceutical compositions, and their use in the treatment of medical conditions, such as cancer, and in inhibiting HPK1 activity.

Compositions for Treatment of Cystic Fibrosis and Other Chronic Diseases

The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one ABC Transporter modulator compound of Formula A, Formula B, Formula C, or Formula D. The invention also relates to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions.

SUBSTITUTED BICYCLIC AROMATIC CARBOXAMIDE AND UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS

The invention relates to substituted bicyclic aromatic carboxamide and urea derivatives as vanilloid receptor ligands, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.

Substituted Bicyclic Aromatic Carboxamide and Urea Compounds as Vanilloid Receptor Ligands

Substituted bicyclic aromatic carboxamide and urea compounds as vanilloid receptor ligands, pharmaceutical compositions containing these compounds, and a method of using these compounds in the treatment and/or inhibition of pain and further diseases and/or disorders mediated at least in part via the vanilloid receptor 1 (VR1/TRPV1).

MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS

The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.

COMPOSITIONS FOR TREATMENT OF CYSTIC FIBROSIS AND OTHER CHRONIC DISEASES

The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one ABC Transporter modulator compound of Formula A, Formula B, Formula C, or Formula D. The invention also relates to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions.

MONOCYCLIC CGRP RECEPTOR ANTAGONISTS

The present invention is directed to compounds of the formula (I) : (wherein variables A1, A2, A3, A4, A5, A6, A7, A8, G1, G2, G3, G4, J, Q, Ea, Eb, Ec, R6, R7, RPG and Y are as described herein) which are antagonists of CGRP receptors and which are useful in the treatment or prevention of diseases in which CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.

COMPOUNDS AND METHODS OF USE

Selected compounds are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Synthesis and structure-activity studies of novel benzocycloheptanone oxazolidinone antibacterial agents

We describe a novel class of benzocycloheptanone derived oxazolidinone antibacterial agents. The synthesis and antibacterial activities with structure variation is discussed.