14150-94-8

Basic information

• Product Name: 1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE
• Synonyms: 1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE;2(1H)-Pyridinone, 1-methyl-3,5-dinitro-;1-Methyl-3,5-dinitropyridin-2(1H)-one;1-Methyl-3,5-dinitro-1,2-dihydropyridine-2-one;3,5-Dinitro-1-methyl-2-pyridone;1-Methyl-3,5-dinitropyridine-2;1-Methyl-3,5-dinitro-1H-p...;1-Methyl-3,5-dinitropyridine-2(1H)-one
• CAS NO: 14150-94-8
• Molecular Formula: C₆H₅N₃O₅
• Molecular Weight: 199.12
• Product Categories: Pyridines;Building Blocks;C6;Chemical Synthesis;Heterocyclic Building Blocks;Heterocycle-Pyridine series
• Mol File: 14150-94-8.mol
• Article Data: 13

Chemical Properties

• Melting Point: 174-178℃
• Boiling Point: 289.5oC at 760 mmHg
• Flash Point: 128.9oC
• Appearance: /
• Density: 1.60
• Vapor Pressure: 0.00219mmHg at 25°C
• Refractive Index: 1.612
• PKA: -8.36±0.62(Predicted)
• CAS DataBase Reference: 1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE(14150-94-8)
• EPA Substance Registry System: 1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE(14150-94-8)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• WGK Germany: 3
• Hazardous Substances Data: 14150-94-8(Hazardous Substances Data)

Usage

General Description

1-Methyl-3,5-dinitro-1H-pyridin-2-one is a chemical compound with the molecular formula C6H5N3O4. It falls under the category of pyridinones, which are aromatic compounds containing a Pyridine ring substituted at one or more positions by a ketone group. 1-Methyl-3,5-dinitro-1H-pyridin-2-one is often utilized in the field of chemistry for various purposes and studies. As with any compound, proper care and safety measures should be observed when handling and using this chemical, as its properties and interactions can lead to potentially hazardous situations if not managed properly.

InChI:InChI=1/C6H5N3O5/c1-7-3-4(8(11)12)2-5(6(7)10)9(13)14/h2-3H,1H3

Upstream product

• 2459-07-6 methyl pyridine-2-carboxylate 
• 77-78-1 dimethyl sulfate 
• 5418-51-9 5-nitro-2-hydroxypyridine 
• 6332-56-5 2-hydroxy-3-nitropyridine 
• 2980-33-8 2-hydroxy-3,5-dinitropyridine 
• 74-88-4 methyl iodide 
• 37943-43-4 1-methylpyridinium monomethyl sulfuric acid salt 
• 110-86-1 pyridine 
• 694-85-9 1-methyl-2-pyridone 
• 3719-45-7 1-methyl-6-oxo-1,6-dihydro-pyridine-3-carboxylic acid 
• 7697-37-2 nitric acid 
• 412035-58-6 1-methyl-5-nitro-6-oxo-1,6-dihydro-pyridine-3-carboxylic acid 
• 32896-90-5 1-methyl-5-nitro-2(1H)-pyridone 
• 32896-91-6 1-methyl-3-nitropyridin-2(1H)-one 

Downstream Products

• 123792-64-3 6-methyl-3-nitro-5,6,7,8-tetrahydro[1,6]naphthyridine 
• 1073634-01-1 1-(3-nitro-7,8-dihydro-5H-pyrano[4,3-b]pyridin-8-yl)-N,N-bis(phenylmethyl)methanamine 
• 625099-24-3 C₁₅H₁₃N₃O₃ 
• 1082571-25-2 C₁₄H₁₂ClN₃O₂ 
• 570409-63-1 tert-butyl 3-amino-8,8-dimethyl-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate 
• 84531-35-1 5,6,7,8-tetrahydro-3-nitro-quinoline 
• 217302-90-4 5-nitro-2-propylpyridine 
• 6853-29-8 4-amino-3-ethyl-1-nitrobenzene 
• 856849-80-4 2-butyl-5-nitro-pyridine 
• 285124-06-3 4-nitro-2-propyl-aniline 
• 1574541-75-5 1-(2-ethyl-4-nitrophenyl)pyrrolidine 
• 22730-10-5 Diethyl-(4-nitro-2-propyl-phenyl)-amine 

Relevant articles and documents

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DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS

The invention provides dihydroisoquinoline-2(1H)-carboxamide and related compounds, pharmaceutical compositions, and their use in the treatment of medical conditions, such as cancer, and in inhibiting HPK1 activity.

SUBSTITUTED BICYCLIC AROMATIC CARBOXAMIDE AND UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS

The invention relates to substituted bicyclic aromatic carboxamide and urea derivatives as vanilloid receptor ligands, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.

MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS

The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.