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N(3)-benzylthymidine is a chemical compound with the molecular formula C22H24N2O5 and a molecular weight of 392.44 g/mol. It is a derivative of thymidine, a nucleoside found in DNA, in which a benzyl group is attached to the N(3) position of the thymine base. This modification can be used to study the structure and function of DNA and RNA, as well as to develop novel antiviral or anticancer drugs targeting nucleic acid metabolism.

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  • 21473-21-2 Structure
  • Basic information

    1. Product Name: N(3)-benzylthymidine
    2. Synonyms: N(3)-benzylthymidine
    3. CAS NO:21473-21-2
    4. Molecular Formula: C17H20N2O5
    5. Molecular Weight: 332.3511
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 21473-21-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 554.1°Cat760mmHg
    3. Flash Point: 288.9°C
    4. Appearance: /
    5. Density: 1.384g/cm3
    6. Vapor Pressure: 4.13E-13mmHg at 25°C
    7. Refractive Index: 1.628
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: N(3)-benzylthymidine(CAS DataBase Reference)
    11. NIST Chemistry Reference: N(3)-benzylthymidine(21473-21-2)
    12. EPA Substance Registry System: N(3)-benzylthymidine(21473-21-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 21473-21-2(Hazardous Substances Data)

21473-21-2 Usage

Uses

Used in Nucleic Acid Research:
N(3)-benzylthymidine is used as a research tool for studying the structure and function of DNA and RNA. The benzyl group attached to the N(3) position of the thymine base may impart specific chemical and biological properties to the molecule, allowing for the investigation of nucleic acid interactions and mechanisms.
Used in Drug Development:
N(3)-benzylthymidine is used as a potential candidate for developing novel antiviral or anticancer drugs targeting nucleic acid metabolism. The synthetic nature of this compound allows for the exploration of its therapeutic potential in laboratory settings, with the aim of creating new treatments for various diseases.
Used in Laboratory Settings:
Due to its synthetic nature, N(3)-benzylthymidine is mainly used as a research tool in laboratory settings. This allows scientists to explore its properties and potential applications in a controlled environment, facilitating the advancement of nucleic acid research and drug development.

Check Digit Verification of cas no

The CAS Registry Mumber 21473-21-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,4,7 and 3 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 21473-21:
(7*2)+(6*1)+(5*4)+(4*7)+(3*3)+(2*2)+(1*1)=82
82 % 10 = 2
So 21473-21-2 is a valid CAS Registry Number.
InChI:InChI=1/C17H20N2O5/c1-11-8-18(15-7-13(21)14(10-20)24-15)17(23)19(16(11)22)9-12-5-3-2-4-6-12/h2-6,8,13-15,20-21H,7,9-10H2,1H3/t13-,14+,15+/m0/s1

21473-21-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-benzyl-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

1.2 Other means of identification

Product number -
Other names Thymidine,3-(phenylmethyl)-(9CI)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:21473-21-2 SDS

21473-21-2Downstream Products

21473-21-2Relevant articles and documents

Preparation and pharmacological evaluation of N3-substituted thymidine derivatives as central depressants

Kimura,Watanabe,Tateoka,Kondo,Ing Kang Ho,Yamamoto

, p. 1180 - 1182 (1993)

Central depressant effects in mice of N3-substituted thymidines (Td) (1) were examined by intracerebroventricular (i.c.v.) injection. Nine derivatives including the methyl, ethyl, propyl, allyl, benzyl, xylyl and α-phenylethyl derivatives at th

Photoinduced Deoxygenative Borylations of Aliphatic Alcohols

Wu, Jingjing,B?r, Robin M.,Guo, Lin,Noble, Adam,Aggarwal, Varinder K.

supporting information, p. 18830 - 18834 (2019/11/22)

A photochemical method for converting aliphatic alcohols into boronic esters is described. Preactivation of the alcohol as a 2-iodophenyl-thionocarbonate enables a novel Barton–McCombie-type radical deoxygenation that proceeds efficiently with visible light irradiation and without the requirement for a photocatalyst, a radical initiator, or tin or silicon hydrides. The resultant alkyl radical is intercepted by bis(catecholato)diboron, furnishing boronic esters from a diverse range of structurally complex alcohols.

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