214896-18-1

Basic information

• Product Name: Phenol, 2-ethenyl-5-nitro-
• Synonyms: Phenol, 2-ethenyl-5-nitro-
• CAS NO: 214896-18-1
• Molecular Formula: C8H7NO3
• Molecular Weight: 165.15
• Mol File: 214896-18-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Phenol, 2-ethenyl-5-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2-ethenyl-5-nitro-(214896-18-1)
• EPA Substance Registry System: Phenol, 2-ethenyl-5-nitro-(214896-18-1)

Safety Data

• Hazardous Substances Data: 214896-18-1(Hazardous Substances Data)

Upstream product

• 52427-05-1 2-bromo-5-nitrophenol 
• 7486-35-3 tri-n-butyl(vinyl)tin 
• 554-84-7 meta-nitrophenol 
• 74-86-2 acetylene 

Downstream Products

• 207923-07-7 5-amino-2-ethyl-phenol 

Relevant articles and documents

NOVEL QUINAZOLINONES THAT INHIBIT THE FORMATION OF TAU OLIGOMERS AND THEIR METHOD OF USE

Novel quinazolinones useful as inhibitors of tau oligomer formation, useful for the treatment of neurodegenerative diseases and related conditions are disclosed. The invention also relates to the pharmaceutically acceptable salts of said compounds, processes for the preparation of said compounds, intermediates used in the preparation of said compounds, and pharmaceutical compositions containing said compounds. The invention further relates to methods of use of said compounds, salts of said compounds, and said compositions in treating neurodegenerative diseases and related conditions.

Ortho-vinylation reaction of phenols with ethyne

Phenols were vinylated at the ortho-position with ethyne in the presence of SnCl4-Bu3N reagent. The reaction was applicable to phenols possessing either electron-donating or electron-withdrawing groups. 2,6-Divinylphenols were synthe