21563-29-1

Basic information

• Product Name: 4-Bromo-1,8-naphthalic anhydride
• Synonyms: 4-BROMO-1,8-NAPHTHALENEDICARBOXYLIC ANHYDRIDE;6-BROMO-BENZO[DE]ISOCHROMENE-1,3-DIONE;4-Bromonaphthalene-1,8-dicarboxylic anhydride;4-BR0MO-1.8-NAPHTHALIC ANHYDRIDE;4-Bromo-1,8-naphthalic anhydride;2-BROMO-1,8-NAPHTHALIC ANHYDRIDE;8-bromo-1,8-naphthalic anhydride;4-Bromo-1,8-naphthal
• CAS NO: 21563-29-1
• Molecular Formula: C₁₂H₅BrO₃
• Molecular Weight: 277.07
• EINECS: 201-382-3
• Product Categories: Intermediates of Dyes and Pigments
• Mol File: 21563-29-1.mol

Chemical Properties

• Melting Point: 217-219 °C(lit.)
• Boiling Point: 467.2 ºC at 760 mmHg
• Flash Point: 236.3 ºC
• Appearance: loose-shaped white or off-white crystalline powder
• Density: 1.812 g/cm³
• Vapor Pressure: 6.66E-09mmHg at 25°C
• Refractive Index: 1.733
• Storage Temp.: Room temperature.
• CAS DataBase Reference: 4-Bromo-1,8-naphthalic anhydride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Bromo-1,8-naphthalic anhydride(21563-29-1)
• EPA Substance Registry System: 4-Bromo-1,8-naphthalic anhydride(21563-29-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 21563-29-1(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
4-Bromo-1,8-naphthalic anhydride serves as a reagent in organic synthesis, facilitating the creation of a range of chemical products. Its reactivity and structural features make it a valuable component in the synthesis of complex organic molecules.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 4-Bromo-1,8-naphthalic anhydride is utilized as a precursor for the preparation of new drugs. Its unique chemical properties contribute to the development of innovative pharmaceuticals with potential therapeutic applications.
Used in Material Science:
4-Bromo-1,8-naphthalic anhydride is also employed in the preparation of various functional materials. Its integration into material compositions can enhance properties such as fluorescence, which is beneficial for applications in optoelectronics and other advanced material technologies.
Used in Biological Research as a Fluorescent Labeling Reagent:
4-Bromo-1,8-naphthalic anhydride has been applied as a fluorescent labeling reagent for proteins and other biomolecules in biological research. Its fluorescent properties allow for the tracking and visualization of biological processes at the molecular level, aiding in the advancement of life sciences.

InChI:InChI=1/C12H5BrO3/c13-9-5-4-8-10-6(9)2-1-3-7(10)11(14)16-12(8)15/h1-5H

Upstream product

• 5209-31-4 3-bromoacenaphthene 
• 75839-71-3 4-bromophenalenone 
• 39981-72-1 4-hydroxy-1H-phenalene-1-one 
• 75839-69-9 4-aminophenalen-1-one 
• 20371-51-1 3-bromoacenaphthylene 

Downstream Products

• 207594-40-9 2-benzyloxy-6-bromo-benzo[de]isoquinoline-1,3-dione 
• 86202-08-6 6-bromo-2-(p-tolyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione 
• 52821-19-9 4-bromo-3-nitro-1,8-naphthalic anhydride 
• 26559-67-1 3-bromo-7H-benzo[de]benzo[4,5]imidazo[2,1-a]isoquinolin-7-one 
• 1428418-31-8 6-(4,7-bis(4-(N,N-diphenylamino)phenyl)-2H-benzo[d][1,2,3]triazol-2-yl)-2-hexyl-1H-benzo[de]isoquinoline-1,3(2H)-dione 
• 92874-17-4 4-bromo-N-butylnaphthalimide 
• 170804-03-2 4-(1-phenylethynyl)-1,8-naphthalic anhydride 

Relevant articles and documents

Transformations of polycyclic ketones. XV. Ammonolysis of 4-hydroxyphenalenone

The ammonolysis of 4-hydroxyphenalenone leads to the formation of a mixture of isomeric 4- and 7-aminophenalenones, from which the corresponding bromophenalenones were synthesized.The structure of the obtained compounds was determined by oxidation to the known 2- and 4-bromonaphthalic anhydrides.