216167-95-2Relevant articles and documents
Process for preparation of probucol derivatives and polymorphic forms thereof
-
Page/Page column 9, (2008/06/13)
A process is described for the preparation of polymorphic forms of water-soluble derivatives of probucol compounds. The process generally includes reacting a probucol compound with a solution of alkali metal oxide, reacting the salt mixture with a solutio
Discovery of novel phenolic antioxidants as inhibitors of vascular cell adhesion molecule-1 expression for use in chronic inflammatory diseases
Meng, Charles Q.,Somers, Patricia K.,Hoong, Lee K.,Zheng, X. Sharon,Ye, Zhihong,Worsencroft, Kimberly J.,Simpson, Jacob E.,Hotema, Martha R.,Weingarten, M. David,MacDonald, Mathew L.,Hill, Russell R.,Marino, Elaine M.,Suen, Ki-Ling,Luchoomun, Jayraz,Kunsch, Charles,Landers, Laura K.,Stefanopoulos, Dimitria,Howard, Randy B.,Sundell, Cynthia L.,Saxena, Uday,Wasserman, Martin A.,Sikorski, James A.
, p. 6420 - 6432 (2007/10/03)
Vascular cell adhesion molecule-1 (VCAM-1) mediates recruitment of leukocytes to endothelial cells and is implicated in many inflammatory conditions. Since part of the signal transduction pathway that regulates the activation of VCAM-1 expression is redox
Compounds and methods for treating transplant rejection
-
Page column 21, (2008/06/13)
The use of compounds of the formula and pharmaceutically acceptable salts thereof, alone or in combination for the treatment of transplant rejection, wherein the substituents are further defined in the application.
Compounds and methods of treating transplant rejection
-
, (2008/06/13)
The use of compounds of the formula and pharmaceutically acceptable salts thereof, alone or in combination for the treatment of transplant rejection, wherein the substituents are defined in the application.
Compounds and methods for treating transplant rejection
-
, (2008/06/13)
The use of compounds of the formula and pharmaceutically acceptable salts thereof, alone or in combination for the treatment of transplant rejection, wherein the substituents are further defined in the application.