217093-76-0

Basic information

• Product Name: 2-Azabicyclo[2.1.1]hexane-2-carboxylicacid,ethylester(9CI)
• Synonyms: 2-Azabicyclo[2.1.1]hexane-2-carboxylicacid,ethylester(9CI)
• CAS NO: 217093-76-0
• Molecular Formula: C8H13NO2
• Molecular Weight: 155.19
• Product Categories: CARBOXYLICESTER
• Mol File: 217093-76-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Azabicyclo[2.1.1]hexane-2-carboxylicacid,ethylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Azabicyclo[2.1.1]hexane-2-carboxylicacid,ethylester(9CI)(217093-76-0)
• EPA Substance Registry System: 2-Azabicyclo[2.1.1]hexane-2-carboxylicacid,ethylester(9CI)(217093-76-0)

Safety Data

• Hazardous Substances Data: 217093-76-0(Hazardous Substances Data)

Usage

Structure

Bicyclic compound with a nitrogen atom in the bridging ring

Use in Organic Synthesis

Building block for the synthesis of pharmaceutical drugs and biologically active molecules

Applications in Medicinal Chemistry

Utilized for drug synthesis

Chiral Auxiliary in Asymmetric Synthesis

Assists in creating optically pure compounds

Ligand in Catalysis

Enhances chemical reactions in catalytic processes

Potential Applications

Pharmaceutical industry
Agrochemical industry
Material industry

Upstream product

• 217093-73-7 N-(ethoxycarbonyl)-5-anti-6-anti-dibromo-2-azabicyclo<2.1.1>hexane 

Downstream Products

• 871658-02-5 2-azabicyclo[2.1.1]hexane hydrochloride 

Relevant articles and documents

HETROARYL BENZAMIDE DERIVATIVES FOR USE AS GLK ACTIVATORS IN THE TREATMENT OF DIABETES

Compounds of Formula (I) wherein: R1 is hydroxymethyl; R2 is selected from -C(O)NR4R5, SO2NR4R5, S(O)pR4 and HET-2; HET-1 is a 5- or 6-membered, optionally substituted C-linked heteroaryl ring; HET-2 is a 4-, 5- or 6-membered, C- or N-linked optionally substituted heterocyclyl ring; R3 is selected from halo, fluoromethyl, difluoromethyl, trifluoromethyl, methyl, methoxy and cyano; R4 is selected from for example hydrogen, optionally substituted (1-4C)alkyl and HET-2; R5 is hydrogen or (1-4C)alkyl; or R4 and R5 together with the nitrogen atom to which they are attached may form a heterocyclyl ring system as defined by HET-3; HET-3 is for example an optionally substituted N-linked, 4, 5 or 6 membered, saturated or partially unsaturated heterocyclyl ring; p is (independently at each occurrence) 0, 1 or 2; m is 0 or 1; n is 0, 1 or 2; provided that when m is 0, then n is 1 or 2; or a salt, pro drug or solvate thereof, are described. Their use as GLK activators, pharmaceutical compositions containing them, and processes for their preparation are also described.