217192-22-8

Basic information

• Product Name: (4-PYRID-4-YLPHENYL)METHANOL
• Synonyms: 4-(4-HYDROXYMETHYLPHENYL)PYRIDINE;(4-PYRIDIN-4-YL-PHENYL)-METHANOL;(4-PYRID-4-YLPHENYL)METHANOL;4-[4-(Hydroxymethyl)phenyl]pyridine 97%;3-(2-Carboxypyridin-4-yl)benzyl alcohol;3-(2-Fluoropyridin-4-yl)benzyl alcohol;3-(2-Methylpyridin-4-yl)benzyl alcohol;3-(3-Carboxypyridin-4-yl)benzyl alcohol
• CAS NO: 217192-22-8
• Molecular Formula: C₁₂H₁₁NO
• Molecular Weight: 185.22
• Mol File: 217192-22-8.mol

Chemical Properties

• Melting Point: 173 °C
• Boiling Point: 350.2 °C at 760 mmHg
• Flash Point: 165.6 °C
• Appearance: /
• Density: 1.145 g/cm³
• Vapor Pressure: 1.67E-05mmHg at 25°C
• Refractive Index: 1.6
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 13.99±0.10(Predicted)
• CAS DataBase Reference: (4-PYRID-4-YLPHENYL)METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (4-PYRID-4-YLPHENYL)METHANOL(217192-22-8)
• EPA Substance Registry System: (4-PYRID-4-YLPHENYL)METHANOL(217192-22-8)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22-37/38-41
• Safety Statements: 26-39
• Hazardous Substances Data: 217192-22-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(4-PYRID-4-YLPHENYL)METHANOL is used as an intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with potential therapeutic properties.
Used in Agrochemical Industry:
(4-PYRID-4-YLPHENYL)METHANOL is used as a precursor in the production of agrochemicals, aiding in the creation of compounds that can be utilized in agricultural applications such as pesticides and herbicides.
Used in Materials Science Research:
(4-PYRID-4-YLPHENYL)METHANOL is used as a research compound in materials science to explore its potential applications in the development of new materials with unique properties.
Used in Organic Synthesis:
(4-PYRID-4-YLPHENYL)METHANOL is used as a reagent in organic synthesis for its versatile reactivity, enabling the creation of a wide range of organic compounds for various applications.

InChI:InChI=1/C12H11NO/c14-9-10-1-3-11(4-2-10)12-5-7-13-8-6-12/h1-8,14H,9H2

Upstream product

• 873-75-6 4-bromobenzenemethanol 
• 181219-01-2 4-pyridineboronic acid pinacol ester 
• 1692-15-5 4-pyridylboronic acid 
• 873-76-7 para-Chlorobenzyl alcohol 
• 4385-76-6 4-(4-pyridinyl)benzoic acid 
• 99163-12-9 4-(pyridin-4-yl)benzaldehyde 
• 541-41-3 chloroformic acid ethyl ester 
• 1120-87-2 4-bromopyridin 
• 87736-74-1 4-(tert-butyldimethylsiloxymethyl)bromobenzene 

Downstream Products

• 1204185-08-9 4-[4-(chloromethyl)phenyl]pyridine hydrochloride 
• 1141447-96-2 4-(4-(chloromethyl)phenyl)pyridine 
• 1007-48-3 4-acetoxymethylpyridine 
• 1312700-65-4 [4-(4-(hydroxymethyl)phenylpyridinium)ethylbromide][OTf] 

Relevant articles and documents

PYRROLIDINE GLYCOSIDASE INHIBITORS

Compounds of formula (I) wherein A, W, R3b, Z and p have the meaning according to the claims can be employed, inter alia, for the treatment of tauopathies and Alzheimer's disease.

Biaryl pyridine palladacycles nitrogen heterocyclic carbene compound and its preparation and use

The invention discloses an aryl-pyridine cyclic Pd-N heterocyclic carbene compound. The general formula of the compound is described in the specification, wherein X is selected from Cl, Br and I, L is an N-heterocyclic carbene ligand, and Aryl is an aryl. The invention also discloses a preparation method of the compound. The preparation method comprises the following steps of: adding 2-(4-halogen atom phenyl)-pyridine, imidazolium salt, arylboronic acid, halogenated palladium and alkaline into an organic solvent, heating under the protection of gas, filtering after reaction is finished, drying by distillation, and purifying, thus the aryl-pyridine cyclic Pd-N heterocyclic carbene compound is obtained. The compound can serve as a catalyst and is used for catalyzing reaction between halogenated benzyl alcohol and arylboronic acid to synthesize aryl methyl alcohol. The preparation method has the characteristics of various substrates, mild reaction conditions, high yield, economy and high efficiency and has an important practical value.

CARBAMATE DERIVATIVES OF LACTAM BASED N-ACYLETHANOLAMINE ACID AMIDASE (NAAA) INHIBITORS

Described herein are compounds and pharmaceutical compositions which inhibit N-acylethanolamine acid amidase (NAAA). Described herein are methods for synthesizing the compounds set forth herein and methods for formulating these compounds as pharmaceutical compositions which include these compounds. Also described herein are methods of inhibiting NAAA in order to sustain the levels of palmitoylethanolamide (PEA) and other N-acylethanolamines (NAE) that are substrates for NAAA, in conditions characterized by reduced concentrations of NAE. Also, described here are methods of treating and ameliorating pain, inflammation, inflammatory diseases, and other disorders in which modulation of fatty acid ethanolamides is clinically or therapeutically relevant or in which decreased levels of NAE are associated with the disorder.

Tripodal 4-pyridyl-derived host ligands and their metallo-supramolecular chemistry: Stella octangula and bowl-shaped assemblies

The synthesis of five new cyclotriveratrylene derivatives with 4-pyridyl side arms is reported, along with the crystal structures of three of these. Three ligands with extended 4-pyridylphenyl side arms and a ligand derived from cyclotriphenolene have bee

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This invention is directed to substituted (aminoiminomethyl or aminomethyl) dihydrobenzofurans and benzopyrans that inhibit Factor Xa, pharmaceutical compositions comprising these compounds and their use for inhibiting Factor Xa or treating pathological conditions in a patient that may be ameliorated by administration of such compounds. This invention is also is also directed to substituted (aminoiminomethyl or aminomethyl) dihydrobenzofurans and benzopyrans which directly inhibit both Factor Xa and Factor IIa (thrombin), to pharmaceutical compositions comprising these compounds, to intermediates useful for preparing these compounds and to a method of simultaneously directly inhibiting both Factor Xa and Factor IIa (thrombin).

Antithrombotic agents

This application relates to a compound of formula (I), a pharmaceutically acceptable salt of the compound, or a prodrug thereof, as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa, as well as a process for its preparation and intermediates therefor.