21722-66-7 Usage
Uses
Used in Pharmaceutical Applications:
1-(1,3-Benzodioxol-5-ylcarbonyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid is used as a potential pharmaceutical agent for its structural similarity to serotonin, which may allow it to interact with various receptors in the body and produce therapeutic effects.
Used in Biochemical Research:
In the field of biochemical research, 1-(1,3-Benzodioxol-5-ylcarbonyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid is used as a compound for studying its interactions with different biological systems, potentially leading to a better understanding of its effects and applications.
Used in Chemical Synthesis:
1-(1,3-Benzodioxol-5-ylcarbonyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid is used as a starting material or intermediate in the synthesis of other complex organic compounds, particularly those with potential applications in the pharmaceutical or chemical industries.
Used in Drug Development:
Due to its structural complexity and potential for diverse biological effects, 1-(1,3-Benzodioxol-5-ylcarbonyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid is used in drug development as a candidate for the creation of new therapeutic agents, particularly those targeting the serotonin system.
Used in the Chemical Industry:
In the chemical industry, 1-(1,3-Benzodioxol-5-ylcarbonyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid may be used as a specialty chemical for the production of various products, such as dyes, pigments, or other specialty chemicals that require its unique structural features.
Check Digit Verification of cas no
The CAS Registry Mumber 21722-66-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,7,2 and 2 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 21722-66:
(7*2)+(6*1)+(5*7)+(4*2)+(3*2)+(2*6)+(1*6)=87
87 % 10 = 7
So 21722-66-7 is a valid CAS Registry Number.
InChI:InChI=1/C20H17NO6/c1-11-14(9-19(22)23)15-8-13(25-2)4-5-16(15)21(11)20(24)12-3-6-17-18(7-12)27-10-26-17/h3-8H,9-10H2,1-2H3,(H,22,23)
21722-66-7Relevant articles and documents
Chemical structure and anti-inflammatory activity in the group of substituted indole-3-acetic acids
Boltze,Brendler,Jacobi,Opitz,Raddatz,Seidel,Vollbrecht
, p. 1314 - 1325 (2007/10/02)
The chemical structure of the indometacin molecule was systematically modified with the aim of producing a substance with increased anti-inflammatory activity and improved tolerance. In addition to the variations of the methylene group of the indole-3-acetic acid and substituents on the indole nucleus of indometacin, particular attention was paid to the modification of the carboxyl group of the acetic acid side chain. Among the indometacin esters, one derivative, the [1-(4-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetoxy] acetic acid (54), showed an activity approximately twice that of indometacin in the kaolin edema test in the rat paw. Chemical modification of the new compound 54 did not further improve the activity. These studies suggest that specific substitutions on the indole nucleus, in combination with the acetic acid side chain as in 1, and especially the acetoxy acetic acid side chain in 54 are responsible for the high anti-inflammatory activity of this class of substances. Several methods for the synthesis of acemetacin are described.
