Welcome to LookChem.com Sign In|Join Free

CAS

  • or
ethyl 1,6-dimethyl-2-oxo-4-(2-thienyl)-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

219814-90-1 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 219814-90-1 Structure
  • Basic information

    1. Product Name: ethyl 1,6-dimethyl-2-oxo-4-(2-thienyl)-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate
    2. Synonyms: ethyl 1,6-dimethyl-2-oxo-4-(2-thienyl)-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate
    3. CAS NO:219814-90-1
    4. Molecular Formula: C13H16N2O3S
    5. Molecular Weight: 280.34274
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 219814-90-1.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: ethyl 1,6-dimethyl-2-oxo-4-(2-thienyl)-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate(CAS DataBase Reference)
    10. NIST Chemistry Reference: ethyl 1,6-dimethyl-2-oxo-4-(2-thienyl)-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate(219814-90-1)
    11. EPA Substance Registry System: ethyl 1,6-dimethyl-2-oxo-4-(2-thienyl)-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate(219814-90-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 219814-90-1(Hazardous Substances Data)

219814-90-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 219814-90-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,9,8,1 and 4 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 219814-90:
(8*2)+(7*1)+(6*9)+(5*8)+(4*1)+(3*4)+(2*9)+(1*0)=151
151 % 10 = 1
So 219814-90-1 is a valid CAS Registry Number.

219814-90-1Downstream Products

219814-90-1Relevant articles and documents

Discovery of 3,4-dihydropyrimidin-2(1 H)-ones as a novel class of potent and selective A2B adenosine receptor antagonists

Crespo, Abel,El Maatougui, Abdelaziz,Biagini, Pierfrancesco,Azuaje, Jhonny,Coelho, Alberto,Brea, Jose,Loza, Maria Isabel,Cadavid, Maria Isabel,Garcia-Mera, Xerardo,Gutierrez-De-Teran, Hugo,Sotelo, Eddy

, p. 1031 - 1036 (2013)

We describe the discovery and optimization of 3,4-dihydropyrimidin-2(1H)- ones as a novel family of (nonxanthine) A2B receptor antagonists that exhibit an unusually high selectivity profile. The Biginelli-based hit optimization process enabled a thoughtful exploration of the structure-activity and structure-selectivity relationships for this chemotype, enabling the identification of ligands that combine structural simplicity with excellent hA2B AdoR affinity and remarkable selectivity profiles.

3,4-Dihydropyrimidin-2(1 H)-ones as Antagonists of the Human A2BAdenosine Receptor: Optimization, Structure-Activity Relationship Studies, and Enantiospecific Recognition

Majellaro, María,Jespers, Willem,Crespo, Abel,Nú?ez, María J.,Novio, Silvia,Azuaje, Jhonny,Prieto-Díaz, Rubén,Gioé, Claudia,Alispahic, Belma,Brea, José,Loza, María I.,Freire-Garabal, Manuel,Garcia-Santiago, Carlota,Rodríguez-García, Carlos,García-Mera, Xerardo,Caama?o, Olga,Fernandez-Masaguer, Christian,Sardina, Javier F.,Stefanachi, Angela,El Maatougui, Abdelaziz,Mallo-Abreu, Ana,?qvist, Johan,Gutiérrez-De-Terán, Hugo,Sotelo, Eddy

supporting information, p. 458 - 480 (2021/01/13)

We present and thoroughly characterize a large collection of 3,4-dihydropyrimidin-2(1H)-ones as A2BAR antagonists, an emerging strategy in cancer (immuno) therapy. Most compounds selectively bind A2BAR, with a number of potent and selective antagonists fu

Solvent-Free Ball-Milling Biginelli Reaction by Subcomponent Synthesis

Sahoo, Prasit Kumar,Bose, Anima,Mal, Prasenjit

supporting information, p. 6994 - 6998 (2015/11/16)

We report here an understanding of systems chemistry on small molecules through covalent mechanochemistry. As a proof-of-concept, the multicomponent Biginelli reaction by subcomponent synthesis was considered as a model system. Reactions were performed un

An efficacious protocol for 4-substituted 3,4-dihydropyrimidinones: Synthesis and calcium channel binding studies

Singh, Kamaljit,Arora, Divya,Falkowski, Danielle,Liu, Qingxin,Moreland, Robert S.

supporting information; experimental part, p. 3258 - 3264 (2009/12/24)

Ethyl 1,2-dihydro-l, 6-dimethyl/6-methyl-2-oxopyrimidine-5carboxylates react with C-nucleophiles as well as the anion of the enantiopure chiral auxiliary (l R, 2 S,5 R) - (-) - methyl (S)p-toluenesulfinate to afford 4-substituted and enantiopure congeners

A highly regio- and chemoselective addition of carbon nucleophiles to pyrimidinones. A new route to C4 elaborated Biginelli compounds

Singh, Kamaljit,Arora, Divya,Singh, Sukhdeep

, p. 1349 - 1352 (2007/10/03)

Ethyl 6-methyl-pyrimidine-2-one-5-carboxylates react with C-nucleophiles in a diversity oriented synthetic sequence to afford C4 substituted congeners of medicinally potent Biginelli dihydropyrimidinones, in a highly regioselective manner.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 219814-90-1