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98-03-3 Usage


Different sources of media describe the Uses of 98-03-3 differently. You can refer to the following data:
1. Thiophene derivatives, introducing thenyl group into organic compounds.
2. 2-Thiophenecarboxaldehyde is used in the synthesis of β-aryl-β-amino acids, urea derivatives. Arylation reagent. Also used to synthesize unsaturated ketones as antiviral and cytotoxic agents.


ChEBI: An aldehyde that is thiphene substituted by a formyl group at position 2.

Synthesis Reference(s)

Synthesis, p. 757, 1976 DOI: 10.1055/s-1976-24193Tetrahedron Letters, 36, p. 455, 1995 DOI: 10.1016/0040-4039(94)02284-I

General Description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Purification Methods

Wash it with 50% HCl and distil it under reduced pressure just before use. It has UV: 234nm (hexane). The Z-oxime has m 144o, 136-138o and 142o (H2O). [Beilstein

Check Digit Verification of cas no

The CAS Registry Mumber 98-03-3 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 9 and 8 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 98-03:
63 % 10 = 3
So 98-03-3 is a valid CAS Registry Number.

98-03-3 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • TCI America

  • (T0725)  2-Thiophenecarboxaldehyde (stabilized with HQ)  >98.0%(GC)

  • 98-03-3

  • 25mL

  • 220.00CNY

  • Detail
  • TCI America

  • (T0725)  2-Thiophenecarboxaldehyde (stabilized with HQ)  >98.0%(GC)

  • 98-03-3

  • 100mL

  • 660.00CNY

  • Detail
  • TCI America

  • (T0725)  2-Thiophenecarboxaldehyde (stabilized with HQ)  >98.0%(GC)

  • 98-03-3

  • 500mL

  • 1,680.00CNY

  • Detail
  • Alfa Aesar

  • (A14344)  Thiophene-2-carboxaldehyde, 98+%   

  • 98-03-3

  • 100g

  • 357.0CNY

  • Detail
  • Alfa Aesar

  • (A14344)  Thiophene-2-carboxaldehyde, 98+%   

  • 98-03-3

  • 500g

  • 1696.0CNY

  • Detail
  • Alfa Aesar

  • (A14344)  Thiophene-2-carboxaldehyde, 98+%   

  • 98-03-3

  • 1000g

  • 3237.0CNY

  • Detail
  • Aldrich

  • (T32409)  2-Thiophenecarboxaldehyde  98%

  • 98-03-3

  • T32409-25G

  • 298.35CNY

  • Detail
  • Aldrich

  • (T32409)  2-Thiophenecarboxaldehyde  98%

  • 98-03-3

  • T32409-100G

  • 575.64CNY

  • Detail



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017


1.1 GHS Product identifier

Product name formylthiophene

1.2 Other means of identification

Product number -
Other names thiophene-2-carbaldehyde

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:98-03-3 SDS

98-03-3Relevant articles and documents



, p. 5183 (1954)


A “universal” catalyst for aerobic oxidations to synthesize (hetero)aromatic aldehydes, ketones, esters, acids, nitriles, and amides

Bartling, Stephan,Beller, Matthias,Chandrashekhar, Vishwas G.,Jagadeesh, Rajenahally V.,Rabeah, Jabor,Rockstroh, Nils,Senthamarai, Thirusangumurugan

supporting information, p. 508 - 531 (2022/02/11)

Functionalized (hetero)aromatic compounds are indispensable chemicals widely used in basic and applied sciences. Among these, especially aromatic aldehydes, ketones, carboxylic acids, esters, nitriles, and amides represent valuable fine and bulk chemicals, which are used in chemical, pharmaceutical, agrochemical, and material industries. For their synthesis, catalytic aerobic oxidation of alcohols constitutes a green, sustainable, and cost-effective process, which should ideally make use of active and selective 3D metals. Here, we report the preparation of graphitic layers encapsulated in Co-nanoparticles by pyrolysis of cobalt-piperazine-tartaric acid complex on carbon as a most general oxidation catalyst. This unique material allows for the synthesis of simple, functionalized, and structurally diverse (hetero)aromatic aldehydes, ketones, carboxylic acids, esters, nitriles, and amides from alcohols in excellent yields in the presence of air.

Characteristic flavor formation of thermally processed N-(1-deoxy-α-D-ribulos-1-yl)-glycine: Decisive role of additional amino acids and promotional effect of glyoxal

Zhan, Huan,Cui, Heping,Yu, Junhe,Hayat, Khizar,Wu, Xian,Zhang, Xiaoming,Ho, Chi-Tang

, (2021/09/28)

The role of amino acids and α-dicarbonyls in the flavor formation of Amadori rearrangement product (ARP) during thermal processing was investigated. Comparisons of the volatile compounds and their concentrations when N-(1-deoxy-α-D-ribulos-1-yl)-glycine r

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