219866-68-9

Basic information

• Product Name: Pentanenitrile, 2,2-difluoro-4,4-dimethyl-3-oxo-
• Synonyms: Pentanenitrile, 2,2-difluoro-4,4-dimethyl-3-oxo-
• CAS NO: 219866-68-9
• Molecular Formula: C7H9F2NO
• Molecular Weight: 0
• Mol File: 219866-68-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Pentanenitrile, 2,2-difluoro-4,4-dimethyl-3-oxo-(CAS DataBase Reference)
• NIST Chemistry Reference: Pentanenitrile, 2,2-difluoro-4,4-dimethyl-3-oxo-(219866-68-9)
• EPA Substance Registry System: Pentanenitrile, 2,2-difluoro-4,4-dimethyl-3-oxo-(219866-68-9)

Safety Data

• Hazardous Substances Data: 219866-68-9(Hazardous Substances Data)

Upstream product

• 59997-51-2 trimethylacetylacetonitrile 

Relevant articles and documents

Catalyzed fluorination of carbonyl compounds

The present invention provides a method of substituting a carbonyl compound with fluorine at the α-position, comprising reaching the carbonyl compound with a fluorinating present of a metal-containing catalyst. The reaction results in replacement of a hydrogen atom by fluorine. The catalyst, which is used in a catalytically effective amount, is preferably a transition metal. In one class of methods the catalyst is a transition metal compound. In another class of methods, the catalyst is an elemental metal, in which case the carbonyl compound has an activating group attached to the carbon atom which is substituted by fluorine.

Elemental fluorine. Part 9 : Catalysis of the direct fluorination of 2-substituted carbonyl compounds

Catalysis of the reaction between fluorine and a range of 2-substituted carbonyl compounds has been investigated. Most notably, the preparation of diethyl-2-fluoromalonate has been achieved in high yield by fluorination of diethylmalonate in the presence of hydrated copper nitrate. Reactions between fluorine and carbanions derived from 2-substituted carbonyl compounds, including phosphonates, sulphones and nitriles, are also discussed.