220239-67-8

Basic information

• Product Name: 2-(Trifluoromethoxy)phenylacetic acid
• Synonyms: 2-(Trifluoromethoxy)phenylacetic acid 98%;2-(Trifluoromethoxy)phenylaceticacid98%;2-(Carboxymethyl)-alpha,alpha,alpha-trifluoroanisole;2-(TRIFLUOROMETHOXY)PHENYLACETIC ACID;RARECHEM AL BO 0857
• CAS NO: 220239-67-8
• Molecular Formula: C₉H₇F₃O₃
• Molecular Weight: 220.15
• EINECS: -0
• Product Categories: Aromatic Phenylacetic Acids and Derivatives;Phenylacetic acid;Fluorine series
• Mol File: 220239-67-8.mol

Chemical Properties

• Melting Point: 54-56°C
• Boiling Point: 247.9°C at 760 mmHg
• Flash Point: 103.7°C
• Appearance: /
• Density: 1.399g/cm³
• Vapor Pressure: 0.0133mmHg at 25°C
• Refractive Index: 1.477
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.02±0.10(Predicted)
• CAS DataBase Reference: 2-(Trifluoromethoxy)phenylacetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Trifluoromethoxy)phenylacetic acid(220239-67-8)
• EPA Substance Registry System: 2-(Trifluoromethoxy)phenylacetic acid(220239-67-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-36
• Safety Statements: 26-36
• HazardClass: IRRITANT
• Hazardous Substances Data: 220239-67-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-(Trifluoromethoxy)phenylacetic acid is utilized as a building block in the synthesis of various pharmaceutical compounds for its anti-inflammatory and analgesic properties. It plays a crucial role in the development of non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents, contributing to the treatment of various conditions that require pain relief and inflammation reduction.
Used in Agricultural Applications:
In the agricultural sector, 2-(Trifluoromethoxy)phenylacetic acid has been studied for its potential use as a herbicide. Its application aims to control and manage unwanted plant growth, thereby enhancing crop productivity and quality. 2-(Trifluoromethoxy)phenylacetic acid's effectiveness in this context is under investigation to ensure its safety and efficacy as an agricultural chemical.

InChI:InChI=1/C9H7F3O3/c10-9(11,12)15-7-4-2-1-3-6(7)5-8(13)14/h1-4H,5H2,(H,13,14)

Upstream product

• 137218-25-8 2-(2-trifluoromethoxyphenyl)acetonitrile 

Downstream Products

• 1030630-28-4 N-methyl-N-(2-pyrrolidin-1-ylethyl)-2-[(2-trifluoromethoxy)phenyl]acetamide 
• 1030630-30-8 N-methyl-N-(2-piperidin-1-ylethyl)-2-[(2-trifluoromethoxy)phenyl]acetamide 
• 1030630-31-9 N-ethyl-N-(2-piperidin-1-ylethyl)-2-[(2-trifluoromethoxy)phenyl]acetamide 
• 1030630-29-5 N-ethyl-N-(2-pyrrolidin-1-ylethyl)-2-[(2-trifluoromethoxy)phenyl]acetamide 
• 1159678-02-0 C₁₁H₁₁F₃O₃ 
• 1159677-92-5 6-(2-trifluoromethoxy-benzyl)-1-(4-trifluoromethyl-pyridin-3-yl)-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one 
• 1262106-53-5 8-[4-fluoro-3-(trifluoromethoxy)phenyl]-3-[3-methoxy-4-(2-methyl-1,3-oxazol-5-yl)phenyl]-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine 
• 1262107-18-5 2-{4-chloro-1-[2-(trifluoromethoxy)phenyl]butyl}-5-[3-methoxy-4-(2-methyl-1,3-oxazol-5-yl)phenyl]-1,3,4-oxadiazole 
• 1262106-52-4 3-[3-methoxy-4-(2-methyl-1,3-oxazol-5-yl)phenyl]-8-[2-(trifluoromethoxy)phenyl]-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine 
• 1262107-19-6 5-chloro-2-[2-(trifluoromethoxy)phenyl]pentanoic acid 
• 1363397-20-9 tert-butyl 4-((2-(2-(trifluoromethoxy)phenyl)acetoyloxy)methyl)thiazol-2-ylcarbamate 
• 509143-10-6 N-[4-(4-dimethylamino-quinazolin-2-ylamino)-cyclohexylmethyl]-2-(2-trifluoromethoxy-phenyl)-acetamide 
• 929612-78-2 2-trifluoromethoxyphenylacetyl chloride 

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