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CAS

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220728-15-4

4-methylphenyl 5-(1-pyrrolidinyl)pentyl ether is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 220728-15-4 Structure

  • Basic information

    1. Product Name: 4-methylphenyl 5-(1-pyrrolidinyl)pentyl ether
    2. Synonyms: 4-methylphenyl 5-(1-pyrrolidinyl)pentyl ether
    3. CAS NO:220728-15-4
    4. Molecular Formula: C16H25NO
    5. Molecular Weight: 247.3758
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 220728-15-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-methylphenyl 5-(1-pyrrolidinyl)pentyl ether(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-methylphenyl 5-(1-pyrrolidinyl)pentyl ether(220728-15-4)
    11. EPA Substance Registry System: 4-methylphenyl 5-(1-pyrrolidinyl)pentyl ether(220728-15-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 220728-15-4(Hazardous Substances Data)

220728-15-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 220728-15-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,0,7,2 and 8 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 220728-15:
(8*2)+(7*2)+(6*0)+(5*7)+(4*2)+(3*8)+(2*1)+(1*5)=104
104 % 10 = 4
So 220728-15-4 is a valid CAS Registry Number.

220728-15-4Downstream Products

220728-15-4Relevant articles and documents

Synthesis of potent non-imidazole histamine H3-receptor antagonists

Ganellin, C. Robin,Leurquin, Fabien,Piripitsi, Antonia,Arrang, Jean-Michel,Garbarg, Monique,Ligneau, Xavier,Schunack, Walter,Schwartz, Jean-Charles

, p. 395 - 404 (2007/10/03)

Histamine has been converted into a non-imidazole H3-receptor histamine antagonist by addition of a 4-phenylbutyl group at the N(α)-position followed by removal of the imidazole ring. The resulting compound, N-ethyl- N-(4-phenylbutyl)amine, remarkably has a Ki = 1.3 μM as an H3 antagonist. Using this as a lead compound, a novel series of homologous O and S isosteric tertiary amines was synthesised and structure-activity studies furnished N- (5-phenoxypentyl)pyrrolidine (Ki = 0.18 ± 0.10 μM, for [3H]histamine release from rat cerebral cortex synaptosomes) which, more importantly, was active in vivo. Substitution of NO2 into the para position of the phenoxy group gave N-(5-p-nitrophenoxypentyl)pyrrolidine, UCL 1972 (Ki= 39 ± 11 nM), ED50 = 1.1 ± 0.6 mg/kg per os in mice on brain tele-methylhistamine levels.

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