220896-14-0

Basic information

• Product Name: 6-chloro-1H-pyrrolo[2,3-b]pyridin-2(3H)-one
• Synonyms: 6-chloro-1H-pyrrolo[2,3-b]pyridin-2(3H)-one;6-Chloro-7-aza-2-oxindole;6-chloro-1H,2H,3H-pyrrolo[2,3-b]pyridin-2-one;2H-Pyrrolo[2,3-b]pyridin-2-one,6-chloro-1,3-dihydro-
• CAS NO: 220896-14-0
• Molecular Formula: C₇H₅ClN₂O
• Molecular Weight: 168.58
• Product Categories: CHIRAL CHEMICALS
• Mol File: 220896-14-0.mol

Chemical Properties

• Boiling Point: 376.001°C at 760 mmHg
• Flash Point: 181.199°C
• Appearance: /
• Density: 1.45g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.61
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 2.49±0.40(Predicted)
• CAS DataBase Reference: 6-chloro-1H-pyrrolo[2,3-b]pyridin-2(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-1H-pyrrolo[2,3-b]pyridin-2(3H)-one(220896-14-0)
• EPA Substance Registry System: 6-chloro-1H-pyrrolo[2,3-b]pyridin-2(3H)-one(220896-14-0)

Safety Data

• Hazardous Substances Data: 220896-14-0(Hazardous Substances Data)

Usage

Uses

Used in Medicinal Chemistry:
6-chloro-1H-pyrrolo[2,3-b]pyridin-2(3H)-one is utilized as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new molecules with enhanced biological activity, making it a valuable component in the creation of novel therapeutic agents.
Used in Drug Development:
In the pharmaceutical industry, 6-chloro-1H-pyrrolo[2,3-b]pyridin-2(3H)-one is employed as a potential antitumor agent. Its pharmacological properties have been studied for their ability to target and inhibit the growth of cancer cells, offering a promising avenue for the development of new cancer treatments.
Used in Organic Chemistry Research:
6-chloro-1H-pyrrolo[2,3-b]pyridin-2(3H)-one serves as a subject of research in organic chemistry, where its synthesis and characterization are explored to understand its reactivity and potential applications in the formation of complex organic molecules.
Used in Medicinal Chemistry Research:
6-chloro-1H-pyrrolo[2,3-b]pyridin-2(3H)-one is also used in medicinal chemistry research to investigate its potential as a lead compound for the development of new drugs. Its structure and properties are analyzed to identify ways to optimize its pharmacological activity and selectivity, with the goal of improving its therapeutic potential.

InChI:InChI=1/C7H5ClN2O/c8-5-2-1-4-3-6(11)10-7(4)9-5/h1-2H,3H2,(H,9,10,11)

Upstream product

• 220896-12-8 7-aza-6-chloro-3,3-dibromo-1,3-dihydro-2H-indol-2-one 
• 295327-28-5 3,3,5-tribromo-6-chloro-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one 
• 55052-27-2 6-chloro-7-azaindole 

Downstream Products

• 1360821-96-0 (3E/Z)-6-chloro-3-(3-chloro-2-fluorobenzylidene)-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one 
• 1581754-84-8 6-chloro-3,3-dimethyl-1H-pyrrolo[2,3-b]pyridin-2(3H)-one 

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