221875-98-5

Basic information

• Product Name: N-(3-AMINO-4-METHYLPHENYL)BENZAMIDE
• Synonyms: N-(3-AMINO-4-METHYLPHENYL)BENZAMIDE
• CAS NO: 221875-98-5
• Molecular Formula: C₁₄H₁₄N₂O
• Molecular Weight: 226.27376
• Mol File: 221875-98-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(3-AMINO-4-METHYLPHENYL)BENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-AMINO-4-METHYLPHENYL)BENZAMIDE(221875-98-5)
• EPA Substance Registry System: N-(3-AMINO-4-METHYLPHENYL)BENZAMIDE(221875-98-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 221875-98-5(Hazardous Substances Data)

Upstream product

• 401597-39-5 N-(4-methyl-3-nitrophenyl)benzamide 
• 98-88-4 benzoyl chloride 
• 119-32-4 4-Methyl-3-nitroanilin 
• 95-80-7 4-methylbenzene-1,3-diamine 

Downstream Products

• 221874-82-4 N-(5-benzamido-2-methylphenyl)-3,4-dimethoxybenzamide 
• 221876-18-2 N-(5benzamido-2-methylphenyl)-3-(chloromethyl)benzamide 
• 221876-19-3 N-(5-benzamido-2-methylphenyl)-4-(chloromethyl)benzamide 
• 1395923-19-9 C₂₅H₂₄N₂O₂ 
• 872332-62-2 N-3-[1-(6-cyclopropylamino-pyrimidin-4-yl)-1H-imidazol-2-yl]-4-methyl-benzene-1,3-diamine 
• 872332-60-0 N-{3-[1-(6-chloro-pyrimidin-4-yl)-1H-imidazol-2-ylamino]-4-methyl-phenyl}-benzamide 
• 1395922-97-0 C₂₉H₂₄N₂O₂ 
• 1395923-54-2 C₂₈H₂₂N₂O₃ 
• 872332-59-7 N-[3-(1H-imidazol-2-ylamino)-4-methyl-phenyl]-benzamide 

Relevant articles and documents

COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING CFTR

The present disclosure is directed to disclosed compounds that modulate, e.g., address underlying defects in cellular processing of CFTR activity.

Compounds and Compositions as Protein Kinase Inhibitors

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly di

COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly di

COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly di

Substituted anilino-quinazoline (or quinoline) compounds and use thereof

The invention concerns amide derivatives of Formula (I), wherein: G is N or CH; R1is a group such as hydroxy, halo, trifluoromethyl, C1-6alkyl and C1-6alkoxy; each of R2and R3is hydrogen, halo, C1-6alkyl, C2-6alkenyl or C2-6alkynyl; R4is a group such as hydrogen, hydroxy, C1-6alkyl, C1-6alkoxy and C3-7cycloalkyl, or R4is of the Formula (IC): —K—J, wherein J is aryl, heteroaryl or heterocyclyl and K is a bond or a group such as oxy and imino, R5is a group such as hydrogen, halo and trifluoromethyl: m is 1-3 and q is 0-4; or pharmaceutically acceptable salts or in vivo cleavable esters thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical conditions mediated by cytokines.

BEZAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES MEDIATED BY CYTOKINES

The invention concerns the use of amide derivatives of formula (I) wherein: R1 and R2 are substituents such as hydroxy, C1-6alkoxy, mercapto, C1-6alkylthio, amino, C1-6alkylamino and di-(C1-6alkyl)amino; m and p are independently 0-3; R3 is C1-4alkyl; q is 0-4; and R4 is aryl or cycloalkyl; or a pharmaceutically acceptable salt thereof in the manufacture of a medicament for use in the treatment of diseases or medical conditions mediated by cytokines

Amide derivatives for the treatment of diseases mediated by cytokines

The invention concerns the use of amide derivatives of formula (I) wherein: R1and R2are substituents such as hydroxy, C1-6alkoxy, mercapto, C1-6alkylthio, amino, C1-6alkylamino and di-(C1-6alkyl)amino; m and p are independently 0-3R3is C1-4alkyl; q is 0-4; and R4is aryl or cycloalkyl; or a pharmaceutically acceptable salt thereof in the manufacture of a medicament for use in the treatment of diseases or medical conditions mediated by cytokines