222044-88-4

Basic information

• Product Name: 11,12-Dihydro-11,12-diphenylindolo[2,3-a]carbazole
• Synonyms: 11,12-Dihydro-11,12-diphenylindolo[2,3-a]carbazole;11,12-diphenyl-11,12-dihydroindolo[2,3-a]carbazole
• CAS NO: 222044-88-4
• Molecular Formula: C30H20N2
• Molecular Weight: 408.4932
• Mol File: 222044-88-4.mol

Chemical Properties

• Boiling Point: 638.5±51.0 °C(Predicted)
• Appearance: /
• Density: 1.21±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 11,12-Dihydro-11,12-diphenylindolo[2,3-a]carbazole(CAS DataBase Reference)
• NIST Chemistry Reference: 11,12-Dihydro-11,12-diphenylindolo[2,3-a]carbazole(222044-88-4)
• EPA Substance Registry System: 11,12-Dihydro-11,12-diphenylindolo[2,3-a]carbazole(222044-88-4)

Safety Data

• Hazardous Substances Data: 222044-88-4(Hazardous Substances Data)

Usage

Uses

Used in Cancer Therapy Applications:
11,12-Dihydro-11,12-diphenylindolo[2,3-a]carbazole is used as an anticancer agent for its ability to inhibit the growth of various cancer cell lines. Its mechanism of action involves targeting the Wnt signaling pathway, which is often dysregulated in cancer cells, leading to uncontrolled cell proliferation and tumor growth. By inhibiting this pathway, 11,12-Dihydro-11,12-diphenylindolo[2,3-a]carbazole has the potential to be a valuable therapeutic agent in the treatment of various types of cancer.
Used in Anti-inflammatory Applications:
11,12-Dihydro-11,12-diphenylindolo[2,3-a]carbazole is used as an anti-inflammatory agent due to its ability to modulate inflammatory processes. Its anti-inflammatory properties can be beneficial in treating conditions characterized by excessive inflammation, such as autoimmune diseases and chronic inflammatory disorders.
Used in Neuroprotective Applications:
11,12-Dihydro-11,12-diphenylindolo[2,3-a]carbazole is used as a neuroprotective agent for its potential to protect neurons from damage and degeneration. Its neuroprotective properties can be valuable in the treatment of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis, where neuronal damage and loss contribute to the progression of these conditions.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 11,12-Dihydro-11,12-diphenylindolo[2,3-a]carbazole is used as a lead compound for the development of new drugs targeting the Wnt signaling pathway. Its potential applications in cancer therapy, anti-inflammatory treatments, and neuroprotection make it a promising candidate for further research and drug development.
Used in Research Applications:
11,12-Dihydro-11,12-diphenylindolo[2,3-a]carbazole is used as a research tool in the study of the Wnt signaling pathway and its role in various biological processes. Its ability to inhibit this pathway makes it a valuable compound for investigating the mechanisms underlying cell proliferation, differentiation, and embryonic development, as well as the role of the Wnt pathway in disease pathogenesis.

Upstream product

• 59-88-1 phenylhydrazine hydrochloride 
• 591-50-4 iodobenzene 
• 60511-85-5 11,12-dihydroindolo[2,3-a]carbazole 
• 765-87-7 cyclohexane-1,2-dione 
• 62-53-3 aniline 
• 1024598-06-8 11-phenyl-11,12-dihydroindolo[2,3-a]carbazole 
• 108-86-1 bromobenzene 
• 530-47-2 N,N-diphenylhydrazine hydrochloride 

Relevant articles and documents

COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF

Provided are the compound represented by Formula 2-K, an organic electric element including a first electrode, a second electrode, and an organic material layer formed between the first electrode and the second electrode, and electronic device thereof, and by including the compound represented by Formula 1 and compound represented by Formula 2 or the compound represented by Formula 2-K in the organic material layer, the driving voltage of the organic electric element can be lowered, and the luminous efficiency and life time of the organic electric element can be improved.

Transition-metal free synthesis of: N -aryl carbazoles and their extended analogs

Herein, we describe a facile synthesis of N-arylated carbazoles via ladderization of fluorinated oligophenylenes. The reaction consists of two subsequent nucleophilic substitutions triggered by an electronic transfer from dimsyl anions. The reaction allows the effective one-pot formation of at least six C-N bonds with pronounced selectivity to the C-F bond placement.

Composition Organic photoelectric device and display device

The present invention relates to a composition comprising a first compound represented by chemical formula 1 and a second compound represented by chemical formula 2 or chemical formula 3, an organic optoelectronic device, and a display device. In chemical formulas 1 to 3, each substituent is as defined in the specification. The present invention is able to implement an organic optoelectronic device of high efficiency and long life.

Phosphorescent host material and application thereof

The present invention discloses a phosphorescent host material, the phosphorescent host material at least comprises an electron transport (N-type) host material H1 and a hole transport (P-type) host material H2, and H1 and H2 are respectively selected fro

Composition, organic optoelectronic device and display device

The invention discloses a composition, an organic optoelectronic device and a display device. The composition comprises a first composition which is represented by a chemical formula 1 and a second composition that is represented by a chemical formula 2 or a chemical formula 3.

ORGANIC COMPOUND AND COMPOSITION AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE

The present invention relates to an organic compound represented by chemical formula 1, a composition comprising the same, an organic optoelectronic device, and a display device. In the chemical formula 1, X^1, X^2, Ar^1, Ar^2, L^1 and R^1 to R^6 are as described in the specification. An embodiment provides the organic compound capable of implementing a high-efficiency and long-lived organic optoelectronic device.COPYRIGHT KIPO 2019

ORGANIC COMPOUND AND COMPOSITION AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE

The present invention relates to: an organic compound expressed by a combination of chemical formula 1 and chemical formula 2; a composition comprising the same; an organic optoelectronic device; and a display apparatus. In the chemical formula 1 or the chemical formula 2, X^1, X^2, L^1, L^2, R^1, R^2, and R^3 to R^6 are as defined in the specification. An embodiment provides the organic compound capable of realizing the organic optoelectronic device having high-efficiency and a long lifespan.COPYRIGHT KIPO 2019

ORGANIC COMPOUND AND COMPOSITION AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE

Disclosed are an organic compound represented by Chemical Formula 1, a composition including the same, an organic optoelectronic device, and a display device. In Chemical Formula 1, X1 to X3, Y1 to Y3, and R1 to R18 are the same as described in the detailed description.

Condensed cyclic compound and organic light-emitting device including the same

A condensed cyclic compound represented by Formula 1, wherein, in Formula 1, L1, E1, R1, X11 to X13, X21 to X26, a1, b1 and c1 are described in the specification. An organic light-emiiting device including such a compound is also disclosed.

CONDENSED CYCLIC COMPOUND, AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME

Disclosed are a condensed ring compound and an organic light emitting device comprising the condensed ring compound. The organic light emitting device comprises: a first electrode; a second electrode facing the first electrode; and an organic layer interposed between the first electrode and the second electrode, wherein the organic layer comprises the condensed ring compound.COPYRIGHT KIPO 2015