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2-Quinolineacetonitrile, a-phenyl- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 22297-12-7 Structure
  • Basic information

    1. Product Name: 2-Quinolineacetonitrile, a-phenyl-
    2. Synonyms:
    3. CAS NO:22297-12-7
    4. Molecular Formula: C17H12N2
    5. Molecular Weight: 244.296
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 22297-12-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-Quinolineacetonitrile, a-phenyl-(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-Quinolineacetonitrile, a-phenyl-(22297-12-7)
    11. EPA Substance Registry System: 2-Quinolineacetonitrile, a-phenyl-(22297-12-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 22297-12-7(Hazardous Substances Data)

22297-12-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 22297-12-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,2,9 and 7 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 22297-12:
(7*2)+(6*2)+(5*2)+(4*9)+(3*7)+(2*1)+(1*2)=97
97 % 10 = 7
So 22297-12-7 is a valid CAS Registry Number.

22297-12-7Relevant articles and documents

Anti-viral method

-

, (2008/06/13)

PCT No. PCT/US97/07431 Sec. 371 Date Jan. 6, 1999 Sec. 102(e) Date Jan. 6, 1999 PCT Filed May 2, 1997 PCT Pub. No. WO97/41846 PCT Pub. Date Nov. 13, 1997The present invention provides compounds which inhibit an envelope virus by inhibiting the fusion of the virus with the host cell. The virus may be inhibited in an infected cell, a cell susceptible of infection or a mammal in need thereof.

Urea, thiourea and guanidine compounds and their use as anti-viral agents

-

, (2008/06/13)

The present invention provides compounds which inhibit an envelope virus by inhibiting the fusion of the virus with the host cell. The virus may be inhibited in an infected cell, a cell susceptible of infection or a mammal in need thereof.

Reaction of 2-quinolyl thiocyanate with C-nucleophiles

Iijima,Hiyoshi,Miyashita

, p. 1090 - 1093 (2007/10/02)

2-Quinolyl thiocyanate (2) was found to react with C-nucleophiles, i.e., phenylacetonitrile, p-chlorophenylacetonitrile, p-cyanophenylacetonitrile, p-methoxyphenylacetonitrile, ethyl cyanoacetate, and malononitrile, in two ways, depending on the nature of

REACTION OF METHOXY-N-HETEROAROMATICS WITH PHENYLACETONITRILE UNDER BASIC CONDITIONS

Yamanaka, Hiroshi,Ohba, Setsuya

, p. 895 - 909 (2007/10/02)

The monomethoxyl derivatives of various ?-electron deficient N-heteroaromatics reacted with phenylacetonitrile in tetrahydrofuran in the presence of sodium hydride to give α-phenyl-N-heteroareneacetonitriles in the yields ranging from 45 to 78percent.On the contrary, the reaction of these methoxyl derivatives with ethyl cyanoacetate or malononitrile under similar conditions was restricted within narrow limits.The synthesis of benzoyl-N-heteroaromatics by the air-oxidation of α-phenyl-N-hetroareneacetonitriles was described additionally.

A New Synthesis of Aryl Hetaryl Ketones via SRN1 Reaction of Halogenated Heterocycles withPotassiophenylacetonitrile Followed by Phase-Transfer Catalyzed Decyanation

Hermann, Christine K. F.,Sachdeva, Yesh P.,Wolfe, James F.

, p. 1061 - 1065 (2007/10/02)

Reaction of halogenated pyridines, quinolines, pyrimidines, and pyrazines with potassiophenylacetonitrile (5) in liquid ammonia under near-uv irradiation affords secondary nitriles, which then undergo oxidative decyanation under phase-transfer catalytic conditions to afford aryl hetaryl ketones in excellent yields.

Photostimulated Reactions of 2-Bromopyridine and 2-Chloroquinoline with Nitrile-Stabilized Carbanions and Certain Other Nucleophiles

Moon, Marcus P.,Komin, Andrew P.,Wolfe, James F.,Morris, Gene F.

, p. 2392 - 2399 (2007/10/02)

Potassiophenylacetonitrile (2) reacts with 2-bromopyridine (1) and 2-chloroquinoline (4) via the SRN1 mechanism when the reactants are exposed to near-UV light in liquid NH3.Potassioacetonitrile (6) reacts similarly with 1 and 4 upon photostimulation; however, the photo-SRN1 reaction with 1 is accompanied by SNAr2 amination which becomes the major reaction in the dark or in the presence of di-tert-butyl nitroxide.Substrate 4 undergoes competing SNAr2 amination with amide ion to form 2-aminoquinoline (10) and SN(ANRORC) reactions with both amide ion and carban ion 6 to form 3-methylquinazoline (11) and 2-methyl-3-cyanoquinoline (12), respectively.Formation of 12 becomes the major pathway in reactions between 4 and 6 carried out in the dark. 4-Picolylpotassium (14) reacts with 1, 4, and 4-bromopyridinium chloride (16) under photostimulation to form the appropriate dihetarylmethanes, along with the corresponding amino heterocycles.Amination of 1, 4, and 16 predominates when these reactions are carried out in the dark.Ammonium thiophenoxide (20) undergoes a slow photo-SRN1 reaction with 1 but fails to produce the expected 2-quinolyl phenyl sulfide with 4 after 2 h of irradiation.Potassium salts of acetylene, phenylacetylene, and phthalimide do not react with 1 or 4 after 2 h of exposure to near-UV light.

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