22302-63-2

Basic information

• Product Name: 2-CYANO-N-NAPHTHALEN-1-YL-ACETAMIDE
• Synonyms: 2-cyano-N-naphthalen-1-yl-ethanamide;Acetamide, 2-cyano-N-(1-naphthyl)-
• CAS NO: 22302-63-2
• Molecular Formula: C₁₃H₁₀N₂O
• Molecular Weight: 210.24
• Mol File: 22302-63-2.mol

Chemical Properties

• Melting Point: 175 °C(Solv: benzene (71-43-2))
• Boiling Point: 498.8°Cat760mmHg
• Flash Point: 255.5°C
• Appearance: /
• Density: 1.262g/cm³
• Vapor Pressure: 4.39E-10mmHg at 25°C
• Refractive Index: 1.679
• PKA: -1.03±0.10(Predicted)
• CAS DataBase Reference: 2-CYANO-N-NAPHTHALEN-1-YL-ACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CYANO-N-NAPHTHALEN-1-YL-ACETAMIDE(22302-63-2)
• EPA Substance Registry System: 2-CYANO-N-NAPHTHALEN-1-YL-ACETAMIDE(22302-63-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 22302-63-2(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
2-Cyano-N-naphthalen-1-yl-acetamide is used as a key intermediate in the synthesis of a wide range of chemical compounds. Its unique structure and reactivity make it a valuable building block for creating new molecules with diverse applications across various industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Cyano-N-naphthalen-1-yl-acetamide is used as a starting material for the development of new drugs. Its chemical properties allow for the creation of novel drug candidates that can potentially address unmet medical needs and improve patient outcomes.
Used in Material Science:
2-Cyano-N-naphthalen-1-yl-acetamide is also utilized in material science for the synthesis of advanced materials with specific properties. These materials can be used in various applications, such as electronics, coatings, and adhesives, where their unique characteristics are beneficial.
Used in Research and Development:
In the field of research and development, 2-Cyano-N-naphthalen-1-yl-acetamide serves as a valuable compound for studying chemical reactions and exploring new synthetic pathways. Its versatility and reactivity make it an essential tool for chemists working on innovative projects and breakthrough discoveries.

InChI:InChI=1/C13H10N2O/c14-9-8-13(16)15-12-7-3-5-10-4-1-2-6-11(10)12/h1-7H,8H2,(H,15,16)

Upstream product

• 134-32-7 1-amino-naphthalene 
• 105-56-6 ethyl 2-cyanoacetate 
• 105-34-0 methyl 2-cyanoacetate 

Relevant articles and documents

α-Cyanocinnamide derivatives: A new family of non-peptide, non-sulfhydryl inhibitors of ras farnesylation

Farnesylation of Ras and other proteins is required for their membrane attachment and normal function. Here we report on the synthesis of α-cyanocinnamide derivatives, a new family of farnesyltransferase inhibitors. These compounds are nonpeptidic and do not contain sulfhydryl groups. The most potent compound is a pure competitive inhibitor with respect to the Ras protein and mixed competitive with respect to farnesyl diphosphate. Selectivity studies against geranylgeranyltransferase and biological activities of selected compounds are described. Copyright (C) 1999.