223788-34-9

Basic information

• Product Name: (3-AMINO-1-BENZOFURAN-2-YL)(4-METHOXYPHENYL)METHANONE
• Synonyms: (3-AMINO-BENZOFURAN-2-YL)-(4-METHOXY-PHENYL)-METHANONE;(3-AMINO-1-BENZOFURAN-2-YL)(4-METHOXYPHENYL)METHANONE;AKOS BBS-00001264;3-AMINO-2-(4-METHOXYLBENZOYL)BENZOFURAN
• CAS NO: 223788-34-9
• Molecular Formula: C₁₆H₁₃NO₃
• Molecular Weight: 267.28
• Mol File: 223788-34-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3-AMINO-1-BENZOFURAN-2-YL)(4-METHOXYPHENYL)METHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: (3-AMINO-1-BENZOFURAN-2-YL)(4-METHOXYPHENYL)METHANONE(223788-34-9)
• EPA Substance Registry System: (3-AMINO-1-BENZOFURAN-2-YL)(4-METHOXYPHENYL)METHANONE(223788-34-9)

Safety Data

• Hazardous Substances Data: 223788-34-9(Hazardous Substances Data)

Upstream product

• 611-20-1 salicylonitrile 
• 2632-13-5 2-Bromo-4'-methoxyacetophenone 
• 301538-60-3 2-[2-(4-Methoxyphenyl)-2-oxoethoxy]benzonitrile 

Downstream Products

• 301538-52-3 2-(4-Hydroxybenzoyl)-1-benzofuran-3-amine 
• 187152-50-7 1-(2-methoxy-benzyl)-4-(4-methoxy-phenyl)-2-oxo-1,2-dihydro-benzo[4,5]furo[3,2-b]pyridine-3-carboxylic acid ethyl ester 
• 223788-36-1 [3-(2-methoxy-benzylamino)-benzofuran-2-yl]-(4-methoxy-phenyl)-methanone 
• 301538-64-7 Ethyl {4-[(3-amino-1-benzofuran-2-yl)carbonyl]phenoxy}acetate 
• 223788-35-0 2,2,2-trifluoro-N-[2-(4-methoxy-benzoyl)-benzofuran-3-yl]-acetamide 

Relevant articles and documents

Synthesis and biological evaluation of benzofuran-based 3,4,5-trimethoxybenzamide derivatives as novel tubulin polymerization inhibitors

A new series of derivatives characterized by the presence of the 3,4,5-trimethoxylbenzamide substituted benzofurans were synthesized and evaluated for antiproliferative activity against four cancer cell lines and one normal human cell line. Among them, de

Synthesis and analgesic activity of some substituted 1-benzofurans and 1-benzothiophenes

2-Benzoyl-and 2-(pyridylcarbonyl)-1-benzofuran-3-amines were prepared from 2-hydroxybenzonitrile and corresponding bromoethanone derivatives. 2-Benzoyl-and 2-(pyridylcarbonyl)-1-benzothiophene-3-amines were prepared analogously from 2-sulfanyl-benzonitril

Benzofuro[3,2-b]pyridines as mixed ET(A)/ET(B) and selective ET(B) endothelin receptor antagonists

The discovery, synthesis and structure-activity relationships of a series of novel benzofuro[3,2b]pyridines as non-selective endothelin ET(A)/ET(B) as well as selective ET(B) receptor antagonists are described. The most potent non-selective inhibitor 7s d

Three-step synthesis of an array of substituted benzofurans using polymer-supported reagents

An efficient combinatorial route to substituted 3-phenyl-benzofurans, is achieved by the bromination of acetophenones to α-bromoacetophenones by polymer-supported pyridinium bromide perbromide (PSPBP). The subsequent clean substitution of the obtained bromides by phenols using 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD-P) and cyclodehydration of the resulting α-phenoxyacetophenones using Amberlyst 15, affords pure products without the need for any chromatographic purification step.