225509-09-1Relevant articles and documents
Asymmetric total synthesis of epolactaene. Part 1: Construction of epoxy-γ-lactam moiety and deduction of absolute stereochemistry
Marumoto, Shinji,Kogen, Hiroshi,Naruto, Shunji
, p. 7129 - 7144 (2007/10/03)
Enantioselective construction of the epoxy-γ-lactam moiety of epolactaene (1) was completed in 11 steps from (R)-lactaldehyde derivatives. Key steps include: (i) the stereoselective aldol reaction between (R)lactaldehyde and malonate ester; (ii) diastereo