228107-17-3Relevant articles and documents
Aromaticity-Dependent Regioselectivity in Pd(II)-Catalyzed C-H Direct Arylation of Aryl Ureas
Jiang, Pingping,Li, Feng,Xu, Yongbao,Liu, Qingwen,Wang, Jing,Ding, Hong,Yu, Renfu,Wang, Qifeng
, p. 5918 - 5921 (2015)
Palladium-catalyzed C-H direct arylation generally occurs on the ortho-position of directing groups. By comparing meta-arylated products of 2-naphthyl urea to ortho-arylated products of phenyl urea, the ortho- and meta-regioselectivity of aryl ureas were found to depend on the aromaticity of the corresponding aryl substituents. Thus, aromaticity is a new factor which can affect the regioselectivity in C-H direct arylation. The finding was further confirmed by regioselective direct arylation of indole and pyrrole derivatives.
Asymmetric pyrene derivatives comprising amine group including heteroaryl group and naphthyl group and organic light-emitting diode including the same
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Paragraph 0198; 0207-0210, (2021/02/02)
The present invention relates to a pyrene derivative represented by [chemical formula A] or [chemical formula B], and an organic light emitting diode comprising the same, wherein substituents Py_1, Py_2, Naph_1, and Naph_2, and m are as defined in the detailed description of the invention.
Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 2. Molecular basis of the intrinsic efficacy of arylpiperazine derivatives at the central 5-HT3 receptors
Cappelli, Andrea,Anzini, Maurizio,Vomero, Salvatore,Canullo, Laura,Mennuni, Laura,Makovec, Francesco,Doucet, Edith,Hamon, Michel,Menziani, M. Cristina,De Benedetti, Pier G.,Bruni, Giancarlo,Romeo, Maria R.,Giorgi, Gianluca,Donati, Alessandro
, p. 1556 - 1575 (2007/10/03)
Novel 5-HT3 receptor ligands were designed and synthesized with the aim of obtaining deeper insight into the molecular basis of the intrinsic efficacy of arylpiperazines interacting with the central 5-HT3 receptor. The newly synthesi