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Ethanamine,2,2'-[(1-methylethylidene)bis(thio)]bis-, also known as N,N'-Diisobutylthiourea, is a chemical compound with the molecular formula C8H18N2S2. It is a derivative of thiouurea and is known for its ability to form coordination complexes with metal ions. Ethanamine,2,2'-[(1-methylethylidene)bis(thio)]bisis commonly used as a reagent in organic synthesis and has been studied for its potential applications in various fields.

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  • 22907-30-8 Structure
  • Basic information

    1. Product Name: Ethanamine,2,2'-[(1-methylethylidene)bis(thio)]bis-
    2. Synonyms: Ethylamine,2,2'-(isopropylidenedithio)bis- (8CI)
    3. CAS NO:22907-30-8
    4. Molecular Formula: C7H18 N2 S2
    5. Molecular Weight: 194.365
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 22907-30-8.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Ethanamine,2,2'-[(1-methylethylidene)bis(thio)]bis-(CAS DataBase Reference)
    10. NIST Chemistry Reference: Ethanamine,2,2'-[(1-methylethylidene)bis(thio)]bis-(22907-30-8)
    11. EPA Substance Registry System: Ethanamine,2,2'-[(1-methylethylidene)bis(thio)]bis-(22907-30-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 22907-30-8(Hazardous Substances Data)

22907-30-8 Usage

Uses

Used in Analytical Chemistry:
Ethanamine,2,2'-[(1-methylethylidene)bis(thio)]bisis used as a reagent in organic synthesis for its ability to form coordination complexes with metal ions. This property makes it a valuable tool in analytical chemistry for detecting and analyzing metal ions in various samples.
Used in Treatment of Metal Poisoning:
Ethanamine,2,2'-[(1-methylethylidene)bis(thio)]bishas been studied for its potential applications in the treatment of metal poisoning. Its ability to form coordination complexes with metal ions allows it to bind and help remove toxic metals from the body, providing a potential therapeutic option for heavy metal poisoning.
Used in Pharmaceutical Research:
Ethanamine,2,2'-[(1-methylethylidene)bis(thio)]bishas been investigated for its potential antitumor and antioxidant properties. Its unique chemical structure and ability to form coordination complexes with metal ions make it a promising candidate for further research and development in the pharmaceutical industry.
Used in Organic Synthesis:
Ethanamine,2,2'-[(1-methylethylidene)bis(thio)]bisis commonly used as a reagent in organic synthesis due to its versatile chemical properties. It can be used in the synthesis of various organic compounds, making it a valuable tool in the development of new pharmaceuticals, agrochemicals, and other specialty chemicals.
It is important to handle Ethanamine,2,2'-[(1-methylethylidene)bis(thio)]biswith care, as it can be hazardous if not used properly. Proper safety measures and precautions should be taken when working with this chemical compound.

Check Digit Verification of cas no

The CAS Registry Mumber 22907-30-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,9,0 and 7 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 22907-30:
(7*2)+(6*2)+(5*9)+(4*0)+(3*7)+(2*3)+(1*0)=98
98 % 10 = 8
So 22907-30-8 is a valid CAS Registry Number.

22907-30-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[2-(2-aminoethylsulfanyl)propan-2-ylsulfanyl]ethanamine

1.2 Other means of identification

Product number -
Other names ETHYLAMINE,2,2'-ISOPROPYLIDENEDITHIOBIS

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:22907-30-8 SDS

22907-30-8Downstream Products

22907-30-8Relevant articles and documents

Self-Boosting Catalytic Nanoreactors Integrated with Triggerable Crosslinking Membrane Networks for Initiation of Immunogenic Cell Death by Pyroptosis

Anraku, Yasutaka,Kataoka, Kazunori,Li, Junjie

, p. 13526 - 13530 (2020)

Synthetic polymer vesicles spur novel strategies for producing intelligent nanodevices with precise and specific functions. Engineering vesicular nanodevices with tunable permeability by a general platform without involving trade-offs between structural integrity, flexibility, and functionality remains challenging. Herein, we present a general strategy to construct responsive nanoreactors based on polyion complex vesicles by integrating stimuli-responsive linkers into a crosslinking membrane network. The formulated ROS-responsive nanoreactor with self-boosting catalytic glucose oxidation could protect glucose oxidase (GOD) to achieve cytocidal function by oxidative stress induction and glucose starvation, which is ascribed to stimuli-responsive vesicle expansion without fracture and size-selective cargo release behavior. The GOD-loaded therapeutic nanoreactor induced an immunostimulatory form of cell death by pyroptosis, which has the great potential to prime anti-tumor immune responses.

Amphiphilic nanocage with active oxygen sensitivity, preparation method and application thereof

-

Paragraph 0040-0044, (2020/04/29)

The invention discloses an amphiphilic nanocage with active oxygen sensitivity, a preparation method and application thereof. The amphiphilic nanocage is prepared by the steps of: firstly, forming a nanoemulsion from amphiphilic polybetaine and a thioketal bond-containing small molecular compound with active oxygen sensitivity, and then carrying out reaction under the action of an initiator. The amphiphilic nanocage has amphipathy, high stability, also has active oxygen sensitivity, and can be disintegrated under the action of active oxygen. When the nanocage is a carrier complex protein, theprotein can be included in the nanocage, the protein stability is improved, and transportation of the protein is utilized; after the protein-loaded nanoparticles enter the body, under the action of active oxygen, the external nanocage is disintegrated, and internal protein is released, thus playing a role at a focus part.

A reactive oxygen species-responsive dendrimer with low cytotoxicity for efficient and targeted gene delivery

Wang, Yueqi,Li, Changjian,Du, Libo,Liu, Yang

supporting information, (2019/04/17)

Nonviral vectors have been attracting more attention for several advantages in gene delivery and the development of nonviral gene carriers with high delivery efficiency and low cytotoxicity has long been a key project. Starburst polyamidoamine dendrimers are a class of synthetic polymers with unique structural and physical characteristics. However, when they are used as gene carrier, the gene transfection efficiency is not satisfactory. Herein, a novel thioketal-core polyamidoamine dendrimer (i.e., ROS-PAMAM) was synthesized and characterized. Compared to ethylenediamine-core dendrimers or widely used cationic polymers of polyetherimide, ROS-PAMAM showed lower cytotoxicity. Moreover, ROS-PAMAM demonstrated reactive oxygen species responsive characteristics, which can facilitate the release of siRNA in the tumor microenvironment. In vitro gene transfection experiments based on A549 cells confirmed that siRNA/ROS-PAMAM exhibits high gene transfection efficiency. It is concluded that ROS-PAMAM shows great potential as a generalizable vehicle for gene therapy applications.

PHARMACEUTICAL COMPOSITIONS CONTAINING POLYROTAXANES

-

Page/Page column 15, (2019/10/23)

Disclosed herein are a polyrotaxane conjugated metal chelators and selectively cleavable linkers. The compositions have prolonged plasma residence time, and upon contact with the appropriate chemical environment, are cleaved and then renally and fecally cleared.

A reactive oxygen species (ROS)-responsive polymer for safe, efficient, and targeted gene delivery in cancer cells

Shim, Min Suk,Xia, Younan

supporting information, p. 6926 - 6929 (2013/07/26)

Stimuli-responsive release: The high levels of reactive oxygen species (ROS) in prostate cancer cells can be exploited to trigger cancer-targeted gene delivery. A ROS-responsive thioketal-based cationic polymer was synthesized and functionalization with a cancer-targeting peptide led to selective and enhanced gene transfection in prostate cancer cells (see scheme). Copyright

Radioprotective germanium dithioacetals of cysteamine and methylcysteamine

Fatome,Sentenac-Roumanou,Lion,et al.

, p. 119 - 122 (2007/10/02)

Ten germanium derivatives of cysteamine and methylcysteamine have been synthesized. Their radioprotective activity is higher that that of their thioacetal isologs. The toxicity of these germanium derivatives is higher than or close to the toxicity of thei

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