23102-86-5

Basic information

• Product Name: SODIUM FORMATE-13C
• Synonyms: SODIUM FORMATE-13C;FORMIC-13C ACID, SODIUM SALT;SODIUM FORMATE-13C, 99 ATOM % 13C;Sodium Formate-1-13C;D, 98%);sodium:oxomethanolate
• CAS NO: 23102-86-5
• Molecular Formula: CHO₂*Na
• Molecular Weight: 69.02
• Mol File: 23102-86-5.mol

Chemical Properties

• Melting Point: 259-262 °C(lit.)
• Appearance: /
• Storage Temp.: Refrigerator
• Solubility: Water
• CAS DataBase Reference: SODIUM FORMATE-13C(CAS DataBase Reference)
• NIST Chemistry Reference: SODIUM FORMATE-13C(23102-86-5)
• EPA Substance Registry System: SODIUM FORMATE-13C(23102-86-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 23102-86-5(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
Sodium formate-13C is used as a reagent in various organic reactions and syntheses. It is particularly useful in the preparation of [3,2b]pyridines, a class of nitrogen-containing heterocyclic compounds with potential applications in pharmaceuticals and materials science.
Used in Palladium-Catalyzed Coupling Reactions:
In addition to its use in organic synthesis, sodium formate-13C is also employed in palladium-catalyzed coupling reactions. Specifically, it is used in the coupling of vinyl triflates with organostannanes, a reaction that is important in the synthesis of complex organic molecules and the formation of carbon-carbon bonds.
Used in Chemical Research and Analysis:
Due to the presence of the stable isotope carbon-13, sodium formate-13C is a valuable tool in chemical research and analysis. It can be used to study the mechanisms of various chemical reactions and to track the incorporation of carbon-13 into reaction products, providing valuable insights into reaction pathways and the behavior of isotopes in chemical systems.
Used in Pharmaceutical Industry:
Sodium formate-13C can be used in the pharmaceutical industry for the synthesis of drug candidates and the development of new therapeutic agents. Its use in palladium-catalyzed coupling reactions and the preparation of [3,2b]pyridines can facilitate the synthesis of complex organic molecules with potential medicinal properties.
Used in Materials Science:
In materials science, sodium formate-13C can be used in the synthesis of novel materials with unique properties. The preparation of [3,2b]pyridines and other complex organic molecules can lead to the development of new materials with applications in areas such as electronics, energy storage, and catalysis.

InChI:InChI=1/CH2O2.Na/c2-1-3;/h1H,(H,2,3);/q;+1/p-1/i1+1;/rCHNaO2/c2-4-1-3/h1H/i1+1

Upstream product

• 87081-58-1 sodium hydrogen carbonate-¹³C 
• 497-19-8 sodium carbonate 
• 1633-56-3 (¹³C)-formic acid 
• 124-38-9 carbon dioxide 

Downstream Products

• 1641-69-6 [13C]Carbon monoxide 
• 1310-73-2 sodium hydroxide 
• 110625-18-8 -p-toluic acid 
• 98195-34-7 benzyl<13C>formate 
• 73222-61-4 <1-¹³C>-Ameisensaeure-ethylester 

Relevant articles and documents

Molecular H2O promoted catalytic bicarbonate reduction with methanol into formate over Pd0.5Cu0.5/C under mild hydrothermal conditions

Direct reduction of bicarbonate, a typical product of CO2 captured in alkaline solution, into value-added organics is one promising way to achieve a simplified and green CO2 capture and utilization process. In this work, a new strategy of bicarbonate reduction coupled with methanol oxidation into a dual formation of formate under mild hydrothermal conditions is reported. A 68% formate production efficiency based on the reductant methanol and nearly 100% selectivity of formate were obtained via a Pd0.5Cu0.5/C catalyst at 180 °C. An operando hydrothermal ATR-FTIR study proved that the bicarbonate was reduced by the in situ generated hydrogen from methanol, which was stepwise oxidized to formaldehyde and formic acid. Notably, DFT calculations and a qNMR study of the 13C and 2H (D) isotopic labelling revealed that H2O molecules not only supplied the hydrogen for bicarbonate reduction but also acted as an indispensable promoter to enhance the catalytic performance of Pd0.5Cu0.5/C for methanol activation.

Deprotonation of a formato ligand by a: Cis-coordinated carbyne ligand within a bis(phenolate) tungsten complex

Deprotonation of a formato ligand by a cis-coordinated propylidyne ligand in a tungsten(vi) complex [(OSSO)W(CEt)(OCHO)] (3) that contains a tetradentate bis(phenolato) ligand (OSSO = {1,4-dithiabutanediyl-2,2′-bis(4,6-di-tert-butyl-phenolato)}) gave the dioxo complex [(OSSO)WO2] (4) along with CO, ethylene and propylene as major products of decomposition.

A nanoporous nickel catalyst for selective hydrogenation of carbonates into formic acid in water

An efficient unsupported nanoporous nickel (NiNPore) material for the hydrogenation of carbonates to formic acid (FA) in water was investigated for the first time. NiNPore is an environmentally benign catalyst and it exhibited remarkable catalytic activity in the reduction of a wide range of carbonates to afford formic acid in excellent yields with high selectivity, and maximum values of 86.6% from NaHCO3 and even up to 92.1% from KHCO3 were obtained. The hydrogen pressure and pKa of the carbonates had a significant influence on the formation of FA. The catalyst was easily recovered and could be recycled at least five times without leaching and loss of activity. The present study demonstrated a potential application for the synthesis of FA from CO2 or carbonate compounds.

Hydroesterification of alkenes with sodium formate and alcohols promoted by cooperative catalysis of Ru3(CO)12 and 2-pyridinemethanol

(Figure Presented) A chelation-assisted hydroesterification reaction of alkenes with sodium formate and alcohols that involves cooperative catalysis by Ru3(CO)12 and 2-pyridinemethanol is described. In this three-component coupling reaction, sodium formate serves as the carbon monoxide source.

Water-soluble analogs of [RuCl3(NO)(PPh3) 2] and their catalytic activity in the hydrogenation of carbon dioxide and bicarbonate in aqueous solution

The new water-soluble ruthenium-nitrosyl complexes [RuCl 3(NO)(TPPMS)2] and [RuCl3(NO)(TPPTS) 2] were synthetized and characterized by IR, 1H and 31P NMR spectroscopies. The NO stretching frequencies, v NO = 1870 cm-1 (TPPMS) and 1883 cm-1 (TPPTS) suggest a linear Ru-N-O arrangements. Reactions with OH- yield the corresponding [RuCl3(NO2)(P)2] derivatives, furthermore, [RuH(NO)(P)3] is formed with TPPMS or TPPTS, respectively, under 100 bar H2 pressure. The new complexes are suitable precatalysts for the hydrogenation of carbon dioxide and/or bicarbonate in aqueous solutions up to a tumover frequency of 400 h -1 under relatively mild conditions (30 bar H2, 70 °C).