2315-67-5

Basic information

• Product Name: OCTOXYNOL-3
• Synonyms: OCTOXYNOL-3;OCTOXYNOL-5;2-[4-(1,1,3,3-tetramethylbutyl)phenoxy]ethanol;4-tert-Octylphenol EO;4-tert-Octylphenol Monoethoxylate;2-(4-tert-Octylphenoxy)ethanol;2-[p-(1,1,3,3-TetraMethylbutyl)phenoxy]ethanol;4-tert-Octylphenyl (2-Hydroxyethyl)ether
• CAS NO: 2315-67-5
• Molecular Formula: C₁₆H₂₆O₂
• Molecular Weight: 250.379
• EINECS: 200-662-2
• Product Categories: Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 2315-67-5.mol

Chemical Properties

• Boiling Point: 351.2°Cat760mmHg
• Flash Point: -17℃
• Appearance: /
• Density: 0.962g/cm³
• Storage Temp.: ?20°C
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 14.29±0.10(Predicted)
• BRN: 2114647
• CAS DataBase Reference: OCTOXYNOL-3(CAS DataBase Reference)
• NIST Chemistry Reference: OCTOXYNOL-3(2315-67-5)
• EPA Substance Registry System: OCTOXYNOL-3(2315-67-5)

Safety Data

• Hazard Codes: F,Xi
• Statements: 11-36-52/53-66-67
• Safety Statements: 16-26-61-9
• RIDADR: UN1090 - class 3 - PG 2 - Acetone, solution
• WGK Germany: 1
• Hazardous Substances Data: 2315-67-5(Hazardous Substances Data)

Usage

Uses

Used in Environmental Studies:
OCTOXYNOL-3 is used as a research subject for studying its impact on the male reproductive system of vertebrates, particularly in aquatic species. The application reason is to understand the effects of this environmental pollutant on gonadal intersex, altered sex ratios, and reduced gonad size, which can help in developing strategies to mitigate its harmful effects on aquatic life and ecosystems.

Upstream product

• 75-21-8 oxirane 
• 140-66-9 tert-octylphenol 
• 107-07-3 2-chloro-ethanol 
• 29375-78-8 ethyl acetate 
• 59388-61-3 1,1,3,3-tetramethylbutylphenolate sodium 

Downstream Products

• 86047-69-0 1-(1,1,3,3-tetramethyl-butyl)-4-(2-vinyloxy-ethoxy)-benzene 
• 76790-62-0 ethyl 6-[p-(1',1',3',3'-tetramethylbutyl)phenyl]-3,6-dioxahexanoate 
• 5442-83-1 (p-tert-octylphenoxyethoxyethyl)dimethylamine 
• 1448798-78-4 2-[benzyl(dimethyl)ammonio]ethyl 2-[(2,2,4,4-tetramethylpentane-2-yl)oxy]ethyl phosphate 
• 1448798-79-5 3-[benzyl(dimethyl)ammonio]propyl 2-[(2,2,4,4-tetramethylpentane-2-yl)oxy]ethyl phosphate 
• 1448049-84-0 C₃₈H₆₀O₄ 
• 2315-62-0 9-[p-(1',1',3',3'-tetramethylbutyl)phenyl]-3,6,9-trioxanonanol 
• 2315-61-9 2-{2-[4-(1,1,3,3-tetramethyl-butyl)-phenoxy]-ethoxy}-ethanol 

Relevant articles and documents

Isolation of bacterial strains that produce the endocrine disruptor, octylphenol diethoxylates, in paddy fields

Topsoil samples were collected from 36 different paddy fields in West Japan. Each soil sample was incubated with a basal salt-medium containing 0.2% OPPEO. Twelve samples possessed OPPEO-degrading activity, from which twelve cultures of OPPEO-degrading ba

Synthesis, self-aggregation and biological properties of alkylphosphocholine and alkylphosphohomocholine derivatives of cetyltrimethylammonium bromide, cetylpyridinium bromide, benzalkonium bromide (C16) and benzethonium chloride

A series of alkylphosphocholine and alkylphosphohomocholine derivatives of cetyltrimethylammonium bromide, cetylpyridinium bromide, benzalkonium bromide (C16) and benzethonium chloride have been synthesized. Their physicochemical properties were also investigated. The critical micelle concentration (cmc), the surface tension value at the cmc (γcmc), and the surface area at the surface saturation per head group (Acmc) were determined by means of surface tension measurements. The prepared compounds exhibit significant cytotoxic, antifungal and antiprotozoal activities. Alkylphosphocholines and alkylphosphohomocholines possess higher antifungal activity against Candida albicans in comparison with quaternary ammonium compounds in general. However, quaternary ammonium compounds exhibit significantly higher activity against human tumor cells and pathogenic free-living amoebae Acanthamoeba lugdunensis and Acanthamoeba quina compared to alkylphosphocholines. The relationship between structure, physicochemical properties and biological activity of the tested compounds is discussed.

Method for preparing arylpoly(oxyalkyl) amines

The invention pertains to a process for preparing an arylpoly(oxyalkyl)compound, wherein the process involves reacting a phenol with a halohydrin, and reacting the reaction product with an amino alkyl halide. The invention seeks to provide a less hazardous alternative to conventional preparation processes where arylpoly(oxyalkyl)compounds are made starting from an extremely toxic and hazardous dihalogeno-polyalkylene ether. The preferred arylpoly(oxyalkyl)compound is benzethonium chloride.

Solvent Extraction of Trivalent Yttrium, Holmium, and Erbium by Novel Types of Acidic Organophosphonates

New types of acidic organophosphonates, HR with different hydrophobic groups, were synthesized in order to investigate their extraction behavior for heavy rare earth elements (Y3+, Ho3+, and Er3+) from aqueous acidic chlor