5442-83-1

Basic information

• Product Name: N,N-Dimethyl-2-[2-[p-(1,1,3,3-tetramethylbutyl)phenoxy]ethoxy]ethylamine
• Synonyms: N,N-Dimethyl-2-[2-[p-(1,1,3,3-tetramethylbutyl)phenoxy]ethoxy]ethylamine
• CAS NO: 5442-83-1
• Molecular Formula: C₂₀H₃₅NO₂
• Molecular Weight: 321.5
• Mol File: 5442-83-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 400.9°C at 760 mmHg
• Flash Point: 102.3°C
• Appearance: /
• Density: 0.939g/cm³
• Vapor Pressure: 1.23E-06mmHg at 25°C
• Refractive Index: 1.486
• CAS DataBase Reference: N,N-Dimethyl-2-[2-[p-(1,1,3,3-tetramethylbutyl)phenoxy]ethoxy]ethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-Dimethyl-2-[2-[p-(1,1,3,3-tetramethylbutyl)phenoxy]ethoxy]ethylamine(5442-83-1)
• EPA Substance Registry System: N,N-Dimethyl-2-[2-[p-(1,1,3,3-tetramethylbutyl)phenoxy]ethoxy]ethylamine(5442-83-1)

Safety Data

• Hazardous Substances Data: 5442-83-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C20H35NO2/c1-19(2,3)16-20(4,5)17-8-10-18(11-9-17)23-15-14-22-13-12-21(6)7/h8-11H,12-16H2,1-7H3

Upstream product

• 124-40-3 dimethyl amine 
• 65925-28-2 1-[2-(2-chloroethoxy)ethoxy]-4-(1,1,3,3-tetramethylbutyl)benzene 
• 140-66-9 tert-octylphenol 
• 2315-67-5 2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethanol 
• 107-99-3 2-(dimethylamino)ethyl chloride 
• 1428422-45-0 p-tert-octylphenoxyethoxyethyl bromide 

Downstream Products

• 121-54-0 benzethonium cloride 
• 1428422-43-8 C₂₈H₄₄NO₃⁽¹⁺⁾*Cl^(1-) 

Relevant articles and documents

METHOD FOR PREPARING ARYL POLYOXY ALKYL QUATERNARY AMMONIUM COMPOUND

A method for preparation of an aryl poly(oxalkyl) quaternary ammonium compound is provided, said method comprising steps of: 1) reacting a phenol with a dihalopolyalkylene ether under the action of a phase transfer catalyst, to obtain an arylpoly(oxalkyl) halide; 2) reacting said arylpoly(oxalkyl) halide with an amination reagent under the action of a phase transfer catalyst, to obtain an arylpoly(oxalkyl) amine; 3) reacting said arylpoly(oxalkyl) amine with an alkylation reagent, to obtain an aryl poly(oxalkyl) quaternary ammonium compound; wherein R1 is H or a C1 to C16 alkyl group, located in the ortho, meta or para position; n is an integer of 2 to 6; R2 is H or a C1 to C16 alkyl group; R3 is H or a C1 to C16 alkyl group; R4 is a C1 to C16 alkyl group; X1 is Br or Cl; X is Cl, Br, or I. The preparation method according to the present invention requires low temperature and low pressure, the reaction time is short, and an overall yield can reach 75%. The operation is simple, the cost is low, and the product can be separated easily and have a purity of pharmaceutical grade, thereby facilitating the large-scale production.

Method for preparing arylpoly(oxyalkyl) amines

The invention pertains to a process for preparing an arylpoly(oxyalkyl)compound, wherein the process involves reacting a phenol with a halohydrin, and reacting the reaction product with an amino alkyl halide. The invention seeks to provide a less hazardous alternative to conventional preparation processes where arylpoly(oxyalkyl)compounds are made starting from an extremely toxic and hazardous dihalogeno-polyalkylene ether. The preferred arylpoly(oxyalkyl)compound is benzethonium chloride.