234082-00-9

Basic information

• Product Name: 14-(tert-Butoxy)-14-oxotetradecanoic acid
• Synonyms: 14-(tert-Butoxy)-14-oxotetradecanoic acid
• CAS NO: 234082-00-9
• Molecular Formula: C₁₈H₃₄O₄
• Molecular Weight: 314.46016
• Mol File: 234082-00-9.mol

Chemical Properties

• Melting Point: 51 °C
• Boiling Point: 417.4±18.0 °C(Predicted)
• Appearance: /
• Density: 0.971±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.78±0.10(Predicted)
• CAS DataBase Reference: 14-(tert-Butoxy)-14-oxotetradecanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 14-(tert-Butoxy)-14-oxotetradecanoic acid(234082-00-9)
• EPA Substance Registry System: 14-(tert-Butoxy)-14-oxotetradecanoic acid(234082-00-9)

Safety Data

• Hazardous Substances Data: 234082-00-9(Hazardous Substances Data)

Usage

Uses

Used in Chemical Research and Synthesis:
14-(tert-Butoxy)-14-oxotetradecanoic acid serves as a building block in chemical research and synthesis, enabling the creation of other molecules. Its unique structure allows for the development of novel compounds with potential applications across different fields.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 14-(tert-Butoxy)-14-oxotetradecanoic acid is utilized as a key intermediate in the synthesis of drugs. Its unique chemical properties contribute to the development of new therapeutic agents with improved efficacy and safety profiles.
Used in Agricultural Industry:
14-(tert-Butoxy)-14-oxotetradecanoic acid finds applications in the agricultural sector, where it may be employed as a component in the formulation of agrochemicals. Its chemical structure and properties can contribute to the development of innovative products for crop protection and enhancement of agricultural yields.
Used in Material Science and Technology Development:
14-(tert-Butoxy)-14-oxotetradecanoic acid also holds potential in material science and the development of new technologies. Its unique chemical structure can be leveraged to create advanced materials with specific properties, such as improved stability, reactivity, or selectivity, which can be applied in various industrial processes and technological advancements.

Upstream product

• 821-38-5 1,14-tetradecanedioic acid 
• 75-65-0 tert-butyl alcohol 
• 21646-49-1 tetradecanedioyl dichloride 

Downstream Products

• 234081-80-2 13-[(S)-1-Benzyloxycarbonyl-2-((S)-1,2-bis-hexadecylcarbamoyl-ethylcarbamoyl)-ethylcarbamoyl]-tridecanoic acid tert-butyl ester 
• 234081-90-4 13-[(S)-1-Benzyloxycarbonyl-2-((S)-1,2-bis-hexadecylcarbamoyl-ethylcarbamoyl)-ethylcarbamoyl]-tridecanoic acid 
• 50515-98-5 14-hydroxytetradecanoic acid methyl ester 
• 17278-74-9 14-hydroxymyristic acid 

Relevant articles and documents

MODIFIED RELAXIN POLYPEPTIDES COMPRISING A PHARMACOKINETIC ENHANCER AND USES THEREOF

The present disclosure generally relates to modified relaxin polypeptides, such as modified human relaxin 2 polypeptides, comprising a non-naturally encoded amino acid which is linked to a pharmacokinetic enhancer, and therapeutic uses of such polypeptides, such as for the treatment of cardiovascular conditions (such as heart failure) and/or conditions relating to fibrosis.

A process for preparing a fatty acid derivative method and its application (by machine translation)

The invention discloses a method for preparing a fatty acid derivative method and its application. The first method is the long-chain fatty acid and thionyl chloride reaction, to obtain the acyl chloride; acyl chloride of preparing butanol reaction, then remove chlorine group, and get long-chain fatty acid uncle ding zhi; then and N - hydroxysuccinimide reaction, long-chain fatty acid succinimide and high yield butylacrylate; then with the L - glutamic acid - 1 - tert-butyl reaction, to obtain tert-butyl long-chain fatty acyl - L - Glu - OtBu; with the N - hydroxysuccinimide reaction, to obtain tert-butyl long-chain fatty acyl - L - Glu (OSu)- OtBu; finally [...] butyl long-chain fatty acyl - L - Glu (OSu)- OtBu tert-butyl in removing, and get long-chain fatty acid derivatives. The method routes the operation is simple, quality is controllable, is suitable for industrial production, and low cost, simple purification at the same time, suitable for use in the preparation of high purity insulin analogs. (by machine translation)

Trigger lipids inducing pH-dependent liposome fusion

Aspartic acid-derived artificial lipids (ADLs; s indicates the number of the methylene groups, s=2, 4, 6, 8, 10, 12) (Scheme 1) with various carboxyl alkyl chains as head groups are designed and synthesized, which are incorporated into liposome membranes by sonication. Fluorescence resonance energy transfer (FRET) measurements indicate that ADL6, ADL8 and ADL10 have high lipid-mixing ability in the acidic solution. The other ADLs, however, do not induce remarkable liposome fusion at acidic nor neutral pH. The hydrophobicity of the head groups of ADL6, ADL8 and ADL10 is suitable as triggers of membrane fusion.

Non-peptidic liposome-fusion compounds at acidic pH

Liposomes including aspartic acid-derived artificial lipids (ADL) with various carboxy alkyl chains as head groups (ADLn; n indicates the number of the methylene groups, n = 2,4,6,8,10,12) are prepared, in which ADL6 and ADL8 liposomes induce remarkably high lipid-mixing in the acidic region.