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(R)-1-(2-chloroacetyl)pyrrolidine-2-carboxylic acid is an organic compound characterized by a pyrrolidine backbone, a carboxylic acid functional group, and a chloroacetyl group attached to the pyrrolidine ring. This chiral compound, with the (R)-enantiomer being the specific optical isomer described, may hold potential applications in pharmaceutical research, chemical synthesis, and medicinal chemistry studies due to its unique structural features and reactivity.

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  • 23500-11-0 Structure
  • Basic information

    1. Product Name: (R)-1-(2-chloroacetyl)pyrrolidine-2-carboxylic acid
    2. Synonyms: (R)-1-(2-chloroacetyl)pyrrolidine-2-carboxylic acid
    3. CAS NO:23500-11-0
    4. Molecular Formula: C7H10ClNO3
    5. Molecular Weight: 191.6122
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 23500-11-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (R)-1-(2-chloroacetyl)pyrrolidine-2-carboxylic acid(CAS DataBase Reference)
    10. NIST Chemistry Reference: (R)-1-(2-chloroacetyl)pyrrolidine-2-carboxylic acid(23500-11-0)
    11. EPA Substance Registry System: (R)-1-(2-chloroacetyl)pyrrolidine-2-carboxylic acid(23500-11-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 23500-11-0(Hazardous Substances Data)

23500-11-0 Usage

Uses

Used in Pharmaceutical Research:
(R)-1-(2-chloroacetyl)pyrrolidine-2-carboxylic acid is used as a compound in pharmaceutical research for its unique structural features and reactivity, which may contribute to the development of new drugs and therapies.
Used in Chemical Synthesis:
(R)-1-(2-chloroacetyl)pyrrolidine-2-carboxylic acid is used as a building block in chemical synthesis, allowing for the creation of more complex molecules with potential applications in various industries.
Used in Medicinal Chemistry Studies:
(R)-1-(2-chloroacetyl)pyrrolidine-2-carboxylic acid is used as a subject of study in medicinal chemistry, where its potential biological activity and interactions with biological targets can be explored for the development of novel therapeutic agents.
Used in the Synthesis of Chiral Molecules:
(R)-1-(2-chloroacetyl)pyrrolidine-2-carboxylic acid is used as a starting material or intermediate in the synthesis of chiral molecules, which are essential in various applications, including pharmaceuticals, agrochemicals, and materials science.
Used in the Development of Enantioselective Catalysts:
(R)-1-(2-chloroacetyl)pyrrolidine-2-carboxylic acid, being a chiral compound itself, can be used in the development of enantioselective catalysts that are crucial for producing enantiomerically pure compounds, which are often required for biological activity and pharmaceutical applications.
Used in Analytical Chemistry:
(R)-1-(2-chloroacetyl)pyrrolidine-2-carboxylic acid can be employed as a reference compound or standard in analytical chemistry for the development and validation of methods to determine the enantiomeric purity of chiral compounds.
Used in the Study of Halogenated Compounds:
(R)-1-(2-chloroacetyl)pyrrolidine-2-carboxylic acid, with its halogenated acetyl group, can be used in research focused on the properties, reactivity, and applications of halogenated compounds in various fields, including pharmaceuticals, materials science, and environmental chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 23500-11-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,5,0 and 0 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 23500-11:
(7*2)+(6*3)+(5*5)+(4*0)+(3*0)+(2*1)+(1*1)=60
60 % 10 = 0
So 23500-11-0 is a valid CAS Registry Number.

23500-11-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (2-chloroacetyl)-D-proline

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:23500-11-0 SDS

23500-11-0Downstream Products

23500-11-0Relevant articles and documents

Preparation method of Vildagliptin intermediate

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Paragraph 0007; 0018-0023, (2018/09/12)

The invention belongs to the field of medicine intermediates, and particularly relates to a preparation method of a Vildagliptin intermediate. The preparation method is characterized in that L-prolineand chloroacetyl chloride are used as raw materials to react; in the reaction process, the adding of other solvents is not needed, so that the introducing of other impurities is avoided, and the purity is improved; by adding an acid-binding agent, the hydrochloric acid produced in the reaction is timely neutralized, so that the reaction time is shortened; the yield rate is increased, the productis easy to purify, and the safety and reliability are realized. Compared with the prior art, the preparation method has the advantages that the adding of a large amount of solvent is not needed, the reaction can be performed at room temperature, the energy consumption is decreased, and the environment-friendly effect is realized.

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