23542-51-0

Basic information

• Product Name: 5-NITRO-1-PENTENE
• Synonyms: 5-NITRO-1-PENTENE;5-nitropent-1-ene
• CAS NO: 23542-51-0
• Molecular Formula: C₅H₉NO₂
• Molecular Weight: 115.13
• Product Categories: Acyclic;Alkenes;Organic Building Blocks
• Mol File: 23542-51-0.mol

Chemical Properties

• Boiling Point: 82 °C32 mm Hg(lit.)
• Flash Point: 155 °F
• Appearance: /
• Density: 1.007 g/mL at 25 °C(lit.)
• Vapor Pressure: 2.66mmHg at 25°C
• Refractive Index: n20/D 1.44(lit.)
• Storage Temp.: 2-8°C
• PKA: 8?+-.0.29(Predicted)
• CAS DataBase Reference: 5-NITRO-1-PENTENE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-NITRO-1-PENTENE(23542-51-0)
• EPA Substance Registry System: 5-NITRO-1-PENTENE(23542-51-0)

Safety Data

• Hazard Codes: T
• Statements: 25-43
• Safety Statements: 45
• WGK Germany: 3
• Hazardous Substances Data: 23542-51-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
5-NITRO-1-PENTENE is used as a synthetic intermediate for the production of various pharmaceuticals. Its unique structure allows it to be a key component in the creation of new and existing medications, contributing to the development of healthcare solutions.
Used in Agrochemical Industry:
In the agrochemical sector, 5-NITRO-1-PENTENE is utilized as an intermediate in the synthesis of different agrochemicals. Its application aids in the development of products designed to enhance crop protection and improve agricultural yields.
Used in Specialty Chemicals Industry:
5-NITRO-1-PENTENE is employed as an intermediate for synthesizing specialty chemicals. Its versatility in chemical reactions makes it a valuable component in the production of specific chemical products used across various industries.
Used as a Reagent in Organic Synthesis:
5-NITRO-1-PENTENE is used as a reagent in organic synthesis processes. Its ability to participate in addition and reduction reactions makes it instrumental in the preparation of other useful compounds, expanding the scope of chemical research and development.

InChI:InChI=1/C5H9NO2/c1-2-3-4-5-6(7)8/h2H,1,3-5H2

Upstream product

• 1119-51-3 bromopentene 
• 133367-89-2 1-bromo-1-nitropent-4-ene 

Downstream Products

• 22020-87-7 5-nitro-2-pentanone 
• 1030825-49-0 C₁₈H₂₆N₂O₅ 
• 551-45-1 allethrolone 
• 80350-56-7 3-hydroxy-8-nonene-2,5-dione 
• 7018-92-0 2,5-Undecanedione 
• 33083-83-9 undecan-5-one 
• 925210-07-7 (+/-)-4-methyl-N-(2-(tetrahydro-2H-pyran-2-yloxy)hept-6-en-3-yl)benzene sulfonamide 

Relevant articles and documents

Intermolecular Palladium-Catalyzed Oxidative Fluorocarbonylation of Unactivated Alkenes: Efficient Access to β-Fluorocarboxylic Esters

A novel palladium-catalyzed intermolecular oxidative fluorocarbonylation of alkenes has been developed, in which employment of a cooperative process with electrophilic ArIF2-meidated alkenes activation and palladium-catalyzed carbonylation is c

Iron-mediated oxidative C-H coupling of arenes and alkenes directed by sulfur: An expedient route to dihydrobenzofurans

A novel route to medicinally-relevant dihydrobenzofurans utilises a sulfur-directed C-H ortho-coupling of arenes and unactivated terminal alkenes mediated by iron, and a palladium-catalysed deallylation/heterocyclisation sequence. The iron-mediated coupli

Cascade formation of isoxazoles: Facile base-mediated rearrangement of substituted oxetanes

Give me five! Nitro compounds and oxetan-3-one react through an intriguing cascade sequence to give isoxazole-4-carbaldehydes using inexpensive reagents in a one-pot procedure (see scheme; Ms=methanesulfonyl). A variety of 3-substituted isoxazole-4-carbaldehydes were obtained in high overall yields.

Reduction of Substituted Nitro Compounds with Tri-n-butyltin Hydride

α-Substituted nitro compounds have been reduced with tri-n-butyltin hydride to give replacement of the α-substituent by hydrogen (2-bromo, 2-chloro- and 2-nitro-2-phenylsulphonylpropane to 2-nitropropane; p-nitrobenzyl chloride, bromide, iodide and thiocyanate to p-nitrotoluene; 5-nitrofurfuryl nitrate to 2-methyl-5-nitrofuran and 2-hydroxymethyl-5-nitrofuran; 2-(bromomethyl)-1-methyl-5-nitroimidazole to 1,2-dimethylimidazole). 2-Bromo-2-nitrohept-6-ene and 1-bromo-1-nitrohex-5-ene were reduced to 2-nitrohept-6-ene and 1-nitrohex-5-ene,5-bromo- and 5-phenylsulphonyl-5-nitro-6-phenyl-norborn-6-ene to 5-nitro-6-phenylnorborn-6-ene and 2-iodo-2-nitro-3-(endo-norborn-2-en-5-yl)propane to 2-nitro-3-(endo-norborn-2-en-5-yl)propane without cyclisation of the intermediate alkenyl α-nitroalkyl radicals. 2-Bromo-2-nitrohex-5-ene and 1-bromo-1-nitropent-4-ene were reduced to the respective nitroalkenes at high but at lower cyclisation to 1-methyl-1-nitrocyclopentane and 1-nitrocyclopentane took place.Inhibition studies of the reductions of 2-bromo-2-nitrohex-5-ene and p-nitrobenzyl bromide showed a radical chain mechanism.In some of the reductions at low , radical rearrangement of the intermediate α-nitroalkyl radicals gave the respective ketones.Mechanisms involving (a) addition/elimination and (b) dissociation of intermediate radical anions, are proposed.

Silyl Nitronates in Organic Synthesis. Routes to Heterocycles and Cyclopentanoids. Synthesis of Allethrolone and Calythrone. Acylation and Cyanohydroxylation of Double Bonds. An Exploratory Study

Silyl nitronates are versatile reagents for the preparation of heterocycles by dipolar addition to double bonds.The intermediate isoxazolidines can be transformed to 2-isoxazolines, isoxazoles, furans, dihydrofuranones, pyrazoles, pyridazines and pyridazones.Reduction of 2-isoxazolines with Ti3+ leads to hydroxylated 1,4-diketones, which subsequently can be cyclized to cyclopentenones.Routes to calythrone, rethrolones, prostanoids and a number of naturally occurring dihydrofuranones are devised, as well as synthetic procedures for acylation, preparation of endiones, hydroxyacylation, cyanation and hydroxycyanation of double bonds.