23579-92-2

Basic information

• Product Name: 2-(METHOXYMETHYL)PYRIDINE
• Synonyms: Pyridine, 2-(methoxymethyl)-;2-(METHOXYMETHYL)PYRIDINE;METHYL (2-PICOLYL) ETHER;METHYL 2-PYRIDYLMETHYL ETHER;METHYL-2-METHYLPYRIDYL ETHER;2-(CH3OCH2)-pyridine;2-METHOXYMETHYL PYRIDINE 2-METHOXYMETHYL PYRIDINE;Nsc75841
• CAS NO: 23579-92-2
• Molecular Formula: C₇H₉NO
• Molecular Weight: 123.15
• Product Categories: Heterocycle-Pyridine series
• Mol File: 23579-92-2.mol

Chemical Properties

• Boiling Point: 158.549 °C at 760 mmHg
• Flash Point: 54.836 °C
• Appearance: /
• Density: 1.011 g/cm³
• Vapor Pressure: 3.38mmHg at 25°C
• Refractive Index: 1.496
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.34±0.12(Predicted)
• CAS DataBase Reference: 2-(METHOXYMETHYL)PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(METHOXYMETHYL)PYRIDINE(23579-92-2)
• EPA Substance Registry System: 2-(METHOXYMETHYL)PYRIDINE(23579-92-2)

Safety Data

• Hazard Codes: Xi
• Statements: Xi:刺激性物质
• Hazardous Substances Data: 23579-92-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-(Methoxymethyl)pyridine is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to facilitate the creation of complex molecular structures that can target specific biological pathways.
Used in Agricultural Chemical Industry:
In the agricultural sector, 2-(Methoxymethyl)pyridine is utilized as an intermediate in the production of agricultural chemicals, contributing to the development of effective pest control agents and other crop protection products.
Used in Organic Compounds Synthesis:
2-(Methoxymethyl)pyridine is employed as an intermediate in the preparation of organic compounds, playing a crucial role in the formation of diverse chemical entities for research and commercial applications.
Used as an Industrial Solvent:
2-(Methoxymethyl)pyridine is used as a solvent in various industrial processes, capitalizing on its ability to dissolve a wide range of substances, thus enhancing the efficiency of numerous manufacturing operations.
Safety Considerations:
Given its potential to cause skin and eye irritation, it is imperative to handle 2-(Methoxymethyl)pyridine with caution, employing appropriate personal protective equipment and following established safety protocols to minimize health risks.

InChI:InChI=1/C7H9NO/c1-9-6-7-4-2-3-5-8-7/h2-5H,6H2,1H3

Upstream product

• 4377-33-7 2-chloromethylpyridine 
• 124-41-4 sodium methylate 

Downstream Products

• 77823-45-1 1-methoxy-2-phenyl-indolizine 
• 88274-04-8 2-(4-Fluoro-phenyl)-1-methoxy-indolizine 
• 1430401-34-5 2-(methoxymethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 
• 79283-70-8 [3-Bromo-4-(3-dibutylamino-propoxy)-phenyl]-(1-methoxy-2-phenyl-indolizin-3-yl)-methanone; compound with oxalic acid 
• 79283-66-2 [3-Chloro-4-(3-dibutylamino-propoxy)-phenyl]-(1-methoxy-2-phenyl-indolizin-3-yl)-methanone; compound with oxalic acid 
• 79283-68-4 [3-Bromo-4-(3-dipropylamino-propoxy)-phenyl]-(1-methoxy-2-phenyl-indolizin-3-yl)-methanone; compound with oxalic acid 
• 79283-64-0 [3-Chloro-4-(3-dipropylamino-propoxy)-phenyl]-(1-methoxy-2-phenyl-indolizin-3-yl)-methanone; compound with oxalic acid 
• 79283-62-8 [4-(3-Dibutylamino-propoxy)-phenyl]-(1-methoxy-2-phenyl-indolizin-3-yl)-methanone; compound with oxalic acid 
• 79283-60-6 [4-(3-Dipropylamino-propoxy)-phenyl]-(1-methoxy-2-phenyl-indolizin-3-yl)-methanone; compound with oxalic acid 
• 88274-08-2 [2-(4-Fluoro-phenyl)-1-methoxy-indolizin-3-yl]-(4-hydroxy-3-methoxy-phenyl)-methanone 
• 77823-49-5 (4-Hydroxy-3-methoxy-phenyl)-(1-methoxy-2-phenyl-indolizin-3-yl)-methanone 
• 77823-46-2 1-methoxy-2-phenyl-3-(3-bromo-4-hydroxy-benzoyl)-indolizine 
• 77823-48-4 (3-Chloro-4-hydroxy-phenyl)-(1-methoxy-2-phenyl-indolizin-3-yl)-methanone 
• 77823-47-3 (4-Hydroxy-phenyl)-(1-methoxy-2-phenyl-indolizin-3-yl)-methanone 

Relevant articles and documents

Displacement of Pyridine-2-methanol from Dichloro(pyridine-2-methanolato)gold(III) in Acidic Solution. Ring Opening at Oxygen

The kinetics of displacement of pyridine-2-methanol (N-OH) from dichloro(pyridine-2-methanolato)gold(III), , have been studied in 5percent aqueous methanol at 25 deg C.In the presence of LiCl and perchloric acid the reaction consists of a pre-equilibrium protonation of the oxygen followed, first, by ring opening at oxygen accompanied by the entry of chloride or solvent, and then by displacement of the N-bonded pyridine-2-methanol to give -.This final stage is very similar to the displacement of 2-(methoxymethyl)pyridine (N-OMe) from .The ligand is not displaced in absence of chloride.The reaction between - and excess pyridine-2-methanol in 5percent methanol was also studied at 25 deg C.The initial attachement of the ligand by nitrogen is followed by rapid ring closing and a second molecule of ligand enters more slowly.The final product is + (isomeric form unknown), stabilised by the basic conditions generated by the excess ligand.Monodentate pyridine-2-methanol behaves as if it has a pKa of 5.6 with a steric hindrance comparable to that of 2-methylpyridine.

2-Alkoxy(and 2-alkoxyalkyl)-2-heterocyclic-thioacetamides for inhibiting gastric acid secretion

The compounds are 2-alkoxy(and 2-alkoxyalkyl)-2-heterocyclic-thioacetamides which are inhibitors of gastric acid secretion.