24154-26-5

Basic information

• Product Name: 2,5-DIHYDROXYPYRIDINE
• Synonyms: 2,5-PYRIDINEDIOL;2,5-DIHYDROXYPYRIDINE;5-HYDROXY-2-PYRIDONE;5-Hydroxypyridine-2(1H)-one
• CAS NO: 24154-26-5
• Molecular Formula: C5H5NO2
• Molecular Weight: 111.1
• Mol File: 24154-26-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,5-DIHYDROXYPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-DIHYDROXYPYRIDINE(24154-26-5)
• EPA Substance Registry System: 2,5-DIHYDROXYPYRIDINE(24154-26-5)

Safety Data

• Hazardous Substances Data: 24154-26-5(Hazardous Substances Data)

Usage

Uses

Used in Agricultural Industry:
2,5-Dihydroxypyridine is used as a metabolite in the degradation process of pyriproxyfen, a pesticide specifically designed to target arthropods. Its role in the metabolism of this pesticide contributes to the overall effectiveness of pyriproxyfen in protecting cotton crops from whitefly infestations.
Used in Chemical Research:
As a metabolite of a widely used pesticide, 2,5-dihydroxypyridine may also be utilized in chemical research to better understand the degradation pathways of pyriproxyfen and other related compounds. This knowledge can be applied to develop more effective and environmentally friendly pesticides in the future.
Used in Environmental Monitoring:
The presence of 2,5-dihydroxypyridine in the environment can serve as an indicator of pesticide use and degradation. By monitoring the levels of this compound in soil, water, and other environmental samples, researchers and regulatory agencies can assess the impact of pesticide use on ecosystems and human health.
Used in Pharmaceutical Development:
Although not explicitly mentioned in the provided materials, the structural features of 2,5-dihydroxypyridine may also make it a candidate for pharmaceutical development. Its hydroxyl groups and pyridine ring could potentially be modified to create new drugs with various therapeutic applications.

Upstream product

• 142-08-5 2-Pyridone 
• 116178-39-3 2-ethoxy-5-hydroxypyridine 
• 132433-50-2 5-hydroxy-1-methoxymethyl-2-pyridone 
• 4432-69-3 3-Oxo-2-azabicyclo<2.2.0>hex-5-ene 
• 132433-52-4 4-hydroxymethyl-1,4-oxazepin-5-one 
• 132433-30-8 6-methoxymethyl-6-aza-3-oxatricyclo<3.2.0.0^2,4>heptan-7-one 
• 116178-15-5 6-(tert-butyldimethylsilyl)-6-aza-3-oxatricyclo<3.2.0.0^2,4>heptan-7-one 
• 116178-12-2 2-(tert-butyldimethylsilyl)-2-azabicyclo<2.2.0>hex-5-en-3-one 
• 132433-25-1 2-methoxymethyl-2-azabicyclo<2.2.0>hex-5-en-3-one 
• 132433-20-6 1-(methoxymethyl)pyridin-2(1H)-one 
• 116178-33-7 5-ethoxy-1,4-oxazepine 
• 116178-20-2 6-aza-3-oxatricyclo<3.2.0.0^2,4>heptan-7-one 
• 116178-27-9 1,4-oxazepin-5-one 
• 132433-40-0 4-methoxymethyl-1,4-oxazepin-5-one 

Downstream Products

• 19365-07-2 (RS)-5-hydroxypiperidin-2-one 
• 52065-78-8 piperidine-2,5-dione 

Relevant articles and documents

In-situ radiolysis ESR studies of hydroxypyridones

In situ radiolysis of hydroxypyridones in aqueous solution produces several radicals detected by ESR. These are produced by primary and secondary reactions of hydroxyl radicals. Azaquinoidal structures were detected from 3- and 5-hydroxypyridones.

Improved syntheses of 5-hydroxy-2-pyridones (2,5-dihydroxypyridines)

Improved syntheses of 5-hydroxy-2-pyridone, 6-chloro-5-hydroxy-2-pyridone, 2,4-dihydroxynicotinic acid, and three methyl-substituted 5-hydroxy-2-pyridones are reported. Copyright Taylor & Francis Group, LLC.

A Three-Step Synthesis of δ-Aminolaevulinic Acid

Piperidine-2,5-dione (4) is prepared by catalytic hydrogenation of 5-hydroxy-2-pyridone (3).Ring opening of the lactam 4 with concentrated hydrochloric acid yields the hydrochloride of δ-aminolaevulinic acid (2).