24314-23-6

Basic information

• Product Name: 7-BENZOYLHEPTANOIC ACID
• Synonyms: 7-BENZOYLHEPTANOIC ACID;8-OXO-8-PHENYLOCTANOIC ACID
• CAS NO: 24314-23-6
• Molecular Formula: C₁₄H₁₈O₃
• Molecular Weight: 234.29
• Mol File: 24314-23-6.mol

Chemical Properties

• Melting Point: 84-85 °C(Solv: water (7732-18-5))
• Boiling Point: 407.1±28.0 °C(Predicted)
• Appearance: /
• Density: 1.091±0.06 g/cm3(Predicted)
• PKA: 4.77±0.10(Predicted)
• CAS DataBase Reference: 7-BENZOYLHEPTANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 7-BENZOYLHEPTANOIC ACID(24314-23-6)
• EPA Substance Registry System: 7-BENZOYLHEPTANOIC ACID(24314-23-6)

Safety Data

• Hazardous Substances Data: 24314-23-6(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 91, p. 5886, 1969 DOI: 10.1021/ja01049a040

Upstream product

• 28861-21-4 1,9-diphenylnonane-1,9-dione 
• 10027-07-3 suberoyl chloride 
• 71-43-2 benzene 
• 36867-36-4 1-phenyl-7-(4,4,6-trimethyl-5,6-dihydro-4H-[1,3]oxazin-2-yl)-heptan-1-one 
• 10521-06-9 oxonane-2,9-dione 
• 64-19-7 acetic acid 
• 51100-70-0 ethyl 7-iodoheptanoate 
• 505-48-6 octane-1,8-dioic acid 
• 14996-79-3 2-phenylcyclooctan-1-one 
• 502-49-8 cycloactanone 
• 100-58-3 phenylmagnesium bromide 
• 137407-47-7 (E)-1-phenylcyclooctene 
• 103187-95-7 ethyl 8-oxo-8-phenyloctanoate 
• 25328-90-9 1-phenylcyclooct-1-ene 

Downstream Products

• 855958-24-6 8-phenyl-8-semicarbazono-octanoic acid 
• 89709-64-8 8-Oxo-8-phenyl-octanoic acid (3S,8S,9S,10R,13R,14S,17R)-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester 
• 1234324-40-3 C₂₃H₂₇ClN₂O₃ 
• 94204-09-8 7-Benzoyl-oenanthsaeure-methylester 
• 1242279-45-3 C₂₂H₂₈N₂O₄S 
• 413615-54-0 8-hydroxy-1-phenyl-1-octanone 

Relevant articles and documents

Controlling Chemoselectivity of Catalytic Hydroboration with Light

The ability to selectively react one functional group in the presence of another underpins efficient reaction sequences. Despite many designer catalytic systems being reported for hydroboration reactions, which allow introduction of a functional handle fo

Visible Light-Driven, Copper-Catalyzed Aerobic Oxidative Cleavage of Cycloalkanones

A visible light-driven, copper-catalyzed aerobic oxidative cleavage of cycloalkanones has been presented. A variety of cycloalkanones with varying ring sizes and various α-substituents reacted well to give the distal keto acids or dicarboxylic acids with moderate to good yields.

Oxidative cleavage of alkenes using an in situ generated iodonium ion with oxone as a terminal oxidant

A facile and operationally convenient catalytic procedure for oxidative cleavage of alkenes is described. In situ formed [hydroxy(4-carboxyphenyl) iodonium]ion, 2, from the oxidation of 4-iodobenzoic acid, 1, has been shown to facilitate the cleavage of a variety of alkenes in presence of Oxone as a co-oxidant. Optimization of the reaction conditions using 1-phenyl-1- cyclohexene, 3, and the competitive oxidative cleavage of different substrates using the optimized conditions has uncovered important mechanistic details of the reaction.

(2-Amino-phenyl)-amides of ω-substituted alkanoic acids as new histone deacetylase inhibitors

A variety of ω-substituted alkanoic acid (2-amino-phenyl)-amides were designed and synthesized. These compounds were shown to inhibit recombinant human histone deacetylases (HDACs) with IC50 values in the low micromolar range and induce hyperacetylation of histones in whole cells. They induced expression of p21WAF1/Cip1 and caused cell-cycle arrest in human cancer cells. Compounds in this class showed efficacy in human tumor xenograft models.

Structurally simple trichostatin A-like straight chain hydroxamates as potent histone deacetylase inhibitors

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Liquid Crystalline Properties of Cholesteryl ω-Arylalkanoates

The thermal properties of the homologous series of cholesteryl ω-(4-benzoylphenyl)- (I), ω-(4-benzylphenyl)- (II), ω-benzoyl- (III), and ω-phenoxyalkanoate (IV) have been investigated.For series I and II the cholesteric-isotropic (Ch-I) transition temperatures, enthalpies, and entropies show a remarkable alternation.For series III and IV, the transition temperatures, enthalpies, and entropies exhibit weak alternation and their trends are opposite to those for series I and II, and the cholesteryl ω-phenylalkanoates.The cholesteric-isotropic transition temperatures are discussed in terms of the geometrical and electrical alternations stemming from the terminal aryl groups, and also the relative importance between these two terms.