24449-39-6

Basic information

• Product Name: tectol
• Synonyms: tectol;2,2,2',2'-Tetramethyl-5,5'-bi(2H-naphtho[1,2-b]pyran)-6,6'-diol
• CAS NO: 24449-39-6
• Molecular Formula: C30H26O4
• Molecular Weight: 450.52504
• Mol File: 24449-39-6.mol

Chemical Properties

• Melting Point: 216-218 °C
• Boiling Point: 661.5°Cat760mmHg
• Flash Point: 353.9°C
• Appearance: /
• Density: 1.255g/cm³
• PKA: 8.50±0.40(Predicted)
• CAS DataBase Reference: tectol(CAS DataBase Reference)
• NIST Chemistry Reference: tectol(24449-39-6)
• EPA Substance Registry System: tectol(24449-39-6)

Safety Data

• Hazardous Substances Data: 24449-39-6(Hazardous Substances Data)

Usage

Uses

Tectol can be used to detect inhibitors of human proteases key to treat SARS-CoV-2 infection.

Upstream product

• 89355-02-2 3,10-dihydro-3,3-dimethyl-10-(2-methylprop-1-enyl)naphtho<2,3-d>pyrano<3',2':3,4>naphthol<1,2-b>pyran-11,16-quinone 
• 84-85-5 4-methoxynaphth-1-ol 
• 1425866-87-0 tert-butyl(4-methoxynaphthalen-1-yloxy)dimethylsilane 
• 1425866-90-5 4-(tert-butyldimethylsiloxy)naphthalene-1-ol 
• 1425866-93-8 tert-butyl(2,2-dimethyl-2H-benzo[h]chromen-6-yloxy)dimethylsilane 

Downstream Products

• 89355-02-2 3,10-dihydro-3,3-dimethyl-10-(2-methylprop-1-enyl)naphtho<2,3-d>pyrano<3',2':3,4>naphthol<1,2-b>pyran-11,16-quinone 

Relevant articles and documents

Synthesis of hemitectol, tectol, and tecomaquinone i

The first total syntheses of Tectona grandis (teak) natural products hemitectol and tectol are described. The observation of spontaneous dimerisation of hemitectol to tectol suggests the monomer is the true natural product and that the dimer is an artifact of isolation. Georg Thieme Verlag KG · Stuttgart · New York.

Cetyl triacontanoate and other constituents from Acacia jacquemontii and Kigelia pinnata

Leaves of Acacia jacquemontii on chemical investigation afforded a new aliphatic ester - cetyl triacontanoate along with n-triacontanol, n-octacosanol, β-sitosterol and stigmasterol while the heart wood of Kigelia pinnata gave lapachol, dehydro-α-lapachone, tecomaquinone-I, D-sesamin, paulownin, wodeshiol (kigeliol), klgelinone, β-sitosterol and stigmasterol on reinvestigation. The structures of isolated compounds were ascertained using various spectral (IR, 1H, 13C NMR, MS) techniques.

Radermachol and naphthoquinone derivatives from Tecomella undulata: Complete 1H and 13C NMR assignments of radermachol with the aid of computational 13C shift prediction

Petroleum ether extract of the heartwood of Tecomella undulata affords radermachol, an unusual rare pigment and 2-isopropenylnaphtho[2,3-b]furan-4,9- quinone along with lapachol, tecomaquinone-I, dehydro-α-lapachone, α-lapachone, β-lapachone, cluytyl ferulate, stigmasterol and β-sitosterol. Radermachol and 2-isopropenylnaphtho [2,3-b]furan-4,9-quinone are being reported for the first time from genus Tecomella. Complete assignments of 1H and 13C NMR signals of polyketide, radermachol 1, have been achieved by the 13C NMR chemical shift prediction using ab initio MO and DFT/GIAO methods in addition to 2D-NMR techniques.