248275-70-9

Basic information

• Product Name: 3-Cyclopentene-1-carboxamide,N-methoxy-N-methyl-(9CI)
• Synonyms: 3-Cyclopentene-1-carboxamide,N-methoxy-N-methyl-(9CI);N-Methoxy-N-Methyl-3-cyclopentenecarboxaMide;N-methoxy-N-methyl-3-Cyclopentene-1-carboxamide
• CAS NO: 248275-70-9
• Molecular Formula: C₈H₁₃NO₂
• Molecular Weight: 155.19432
• Product Categories: AMIDE
• Mol File: 248275-70-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Cyclopentene-1-carboxamide,N-methoxy-N-methyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Cyclopentene-1-carboxamide,N-methoxy-N-methyl-(9CI)(248275-70-9)
• EPA Substance Registry System: 3-Cyclopentene-1-carboxamide,N-methoxy-N-methyl-(9CI)(248275-70-9)

Safety Data

• Hazardous Substances Data: 248275-70-9(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
3-Cyclopentene-1-carboxamide,N-methoxy-N-methyl-(9CI) serves as a building block in organic synthesis, contributing to the creation of more complex molecular structures. Its unique functional groups and substituents make it a valuable component in the synthesis of various organic compounds.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-Cyclopentene-1-carboxamide,N-methoxy-N-methyl-(9CI) may be utilized as a starting material for the preparation of other chemical compounds with potential medicinal properties. Its specific structure and functional groups can be key in the development of new drugs or drug candidates.
Used in Chemical Research:
3-Cyclopentene-1-carboxamide,N-methoxy-N-methyl-(9CI) also finds application in chemical research, where it can be employed to study the effects of different substituents on the reactivity and properties of cyclopentene-based compounds. This can lead to a better understanding of chemical reactions and the discovery of new synthetic pathways.

Upstream product

• 7686-77-3 3-cyclopentene-1-carboxylic acid 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 3744-80-7 cyclopent-3-ene-1-carboxylic acid chloride 

Downstream Products

• 861220-70-4 cyclopent-3-enyl-(2,3-difluoro-6-methoxy-phenyl)-methanone 
• 861220-60-2 cyclopent-3-enyl-(2-hydroxy-3,6-dimethoxy-phenyl)-methanone 
• 861220-67-9 cyclopent-3-enyl-(2,4-dimethoxy-phenyl)-methanone 
• 248275-84-5 cyclopent-3-enyl-(2,5-dimethoxy-phenyl)methanone 
• 248275-71-0 cyclopent-3-enyl-(2,6-dimethoxy-phenyl)-methanone 
• 248275-82-3 cyclopent-3-enyl-(2-fluoro-6-methoxy-phenyl)-methanone 
• 248275-72-1 cyclopent-3-enyl-(2-hydroxy-6-methoxy-phenyl)-methanone 
• 861220-68-0 cyclopent-3-enyl-(4-hydroxy-2-methoxy-phenyl)-methanone 
• 861220-65-7 cyclopent-3-enyl-(5-fluoro-2-methoxy-phenyl)-methanone 
• 861220-66-8 2-[3-(cyclopent-3-enecarbonyl)-4-methoxy-phenoxy]-acetamide 
• 861220-62-4 cyclopent-3-enyl-(5-difluoromethoxy-2-methoxy-phenyl)-methanone 
• 861220-63-5 cyclopent-3-enyl-(5-ethoxy-2-methoxy-phenyl)-methanone 
• 861220-61-3 cyclopent-3-enyl-(5-hydroxy-2-methoxy-phenyl)-methanone 
• 861220-64-6 cyclopent-3-enyl-(5-isopropoxy-2-methoxy-phenyl)-methanone 

Relevant articles and documents

Mechanism-Based Design of an Amide-Directed Ni-Catalyzed Arylboration of Cyclopentene Derivatives

A method for amide-directed Ni-catalyzed diastereoselective arylboration of cyclopentenes is disclosed. The reaction allows for the synthesis of sterically congested cyclopentane scaffolds that contain an easily derivatized boronic ester and amide functional handles. The nature of the amide directing group and its influence on the reaction outcome are investigated and ultimately reflect a predictably selective reaction based on the solvent and base counterion.

Zn-ProPhenol Catalyzed Enantioselective Mannich Reaction of 2 H-Azirines with Alkynyl Ketones

The enantioselective Mannich reaction of 2H-azirines with alkynyl ketones is achieved under Zn-ProPhenol catalysis, delivering various aziridines with vicinal tetrasubstituted stereocenters in high yields with excellent enantioselectivities. The bimetalli

THIADIAZINE DERIVATIVES

The invention relates to thiadiazine derivatives, or pharmaceutically acceptable salts, biologically active metabolites, pro-drugs, racemates, enantiomers, diastereomers, solvates and hydrates thereof, as well as to pharmaceutical compositions containing

Copper-Catalyzed Enantioselective Arylative Desymmetrization of Prochiral Cyclopentenes with Diaryliodonium Salts

A copper-catalyzed enantioselective arylative desymmetrization of prochiral cyclopentenes with diaryliodonium salts was developed. In the presence of a catalytic amount of a chiral copper–bisoxazoline complex, which was generated in situ, the reaction of 4-substituted or 4,4-disubstituted cyclopent-1-enes with diaryliodonium hexafluoroarsenates afforded the chiral arylated products in good yields with excellent enantioselectivity. A cyclohexyl-containing Box ligand was essential for the high enantioselectivity. Transformation of the enantiomerically enriched adducts into other chiral building blocks is also documented.

Unexpected Migration and Oxidative Cyclization of Substituted 2-Acetophenone Triflates under Basic Conditions: Synthetic and Mechanistic Insights

Oxidative ring closure of alkyl-substituted 2-hydroxyacetophenone trifluoromethanesulfonate esters (triflates) occurs upon exposure to base in anaerobic DMF at 20-90 °C. Alkyl substitution is required for ring closure. A migrated enol triflate product forms at lower temperature in high yield via migration of the trifluoromethanesulfonate in the unsubstituted and monoalkyl-substituted cases. The alkyl-substituted enol triflates also enter into the benzofuran-3-one ring-forming process under thermal cyclization conditions. Potential mechanistic pathways are evaluated.