cas 24958-44-9, 2-BroMo-5-hydroxy-N-(4-hydroxyphenethyl)-4-Methoxy-N-MethylbenzaMide

Articles about 24958-44-9Total 8 be found

Process for making galantamine
A novel process for the preparation of N-methyl-N-(2-[4-hydroxyphenyl]ethyl)-5-hydroxy-4-methoxy benzene carboxamide, which is useful as an intermediate in the synthesis of (?)-galantamine, comprises the reaction of a 5-hydroxy-4-methoxy benzoic acid derivative with N-methyl-N-(2-[4-hydroxyphenyl]ethyl)amine.
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(2008/12/04)

Alternative total synthesis of (-)-galanthamine hydrobromide
An alternative total synthesis of (-)-galanthamine (1) hydrobromide, employing ecofriendly amidation, oxidative coupling, and classical resolution strategies is accomplished. Copyright Taylor & Francis Group, LLC.
Reddy, Jambula Mukunda,Kumar, Kotagiri Vijay,Raju, Veeramalla,Bhaskar, Bolguddu Vijay,Himabindu, Vurumidi,Bhattacharya, Apurba,Sundaram, Venkatram,Banerjee, Rahul,Reddy, Ghanta Mahesh,Bandichhor, Rakeshwar
p. 2138 - 2149
(2008/09/21)

Syntheses and Preparations of Narwedine and Related Novel Compounds
The present invention relates to a process for preparing racemic narwedine (which can be can be kinetically resolved) to yield (?)-narwedine and which is the biogenic precursor of (?)-galanthamine) and the use thereof as a starting material for producing (?)-galanthamine. The invention further includes processes for preparing (?)-galanthamine and (?)-galanthamine hydrobromide, as well as related novel compounds.
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(2009/01/20)

PROCESS FOR PREPARATION OF BENZAZEPINE
This invention discloses a process for manufacture of galanthamine, which involves a stereoselective reduction step to get the desired isomer of galanthamine. The current embodiment also discusses the method for improving the chiral and chemical purity of galanthamine and galanthamine salts.
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(2008/06/13)

Processes for the preparation of derivatives of 4a, 5, 9, 10, 11, 12-hexahydro-6H-benzofuro-[3a, 3, 2-ef][2]benzazepine
The invention relates to processes for the preparation of 4a,5,9,10,11,12-hexahydro-6H-benzofuro[3a,3,2-ef][2]benzazepine, or derivatives thereof. Furthermore, the invention also relates to the compounds formed during the preparation of 4a, 5,9,10,11,12-hexahydro-6H-benzofuro[3a,3,2-ef][2]benzazepine.
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Example 33

(2008/06/13)

Processes for the preparation of derivatives of 4a,5,9,10,11,12-hexahydro-6H-benzofuro-[3a,3,2-ef][2]benzazepine
The invention relates to processes for the preparation of 4a,5,9,10,11,12-hexahydro-6H-benzofuro(3a,3,2-ef)(2)benzazepine, or derivatives thereof. Furthermore, the invention also relates to the compounds formed during the preparation of 4a,5,9,10,11,12-hexahydro-6H-benzofuro(3a,3,2-ef)(2)benzazepine.
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(2008/06/13)

SYNTHESIS OF GALANTHAMINE AND RELATED ALKALOIDS - NEW APPROARCHES. I.
Modifications of protecting groups and of the oxidative coupling conditions led to pure crystalline intermediates in the synthesis of galanthamine derivatives and gave dienone A in better yields than reported before.The E-configuration of amide 3' in crystalline state has been determined by X-ray diffraction.Streptomyces affinis 6737 reduces A to the optically active (-)-epigalanthamine derivative C, whose absolute configuration was determined by Bijvoet's method.Nematospora corylii CBS 2608 reduces to racemic B.With Ashbya gossypii IFO 1355 a mixture of racemic B and of optically active C is obtained.Some other microbial transformations are described.
Vlahov, Radoslav,Krikorian, Dikran,Spassov, Grigor,Chinova, Maja,Vlahov, Ioncho,et al.
p. 3329 - 3346
(2007/10/02)