24958-44-9

Basic information

• Product Name: 2-BroMo-5-hydroxy-N-(4-hydroxyphenethyl)-4-Methoxy-N-MethylbenzaMide
• Synonyms: 2-BroMo-5-hydroxy-N-(4-hydroxyphenethyl)-4-Methoxy-N-MethylbenzaMide;Benzamide,2-bromo-5-hydroxy-N-[2-(4-hydroxyphenyl)ethyl]-4-methoxy-N-methyl-;2-bromo-5-hydroxy-N-[2-(4-hydroxyphenyl)ethyl]-4-methoxy-N-methylbenzamide
• CAS NO: 24958-44-9
• Molecular Formula: C₁₇H₁₈BrNO₄
• Molecular Weight: 380.23312
• Mol File: 24958-44-9.mol
• Article Data: 8

Chemical Properties

• Melting Point: 288-289 °C
• Boiling Point: 592.1±50.0 °C(Predicted)
• Appearance: /
• Density: 1.468±0.06 g/cm3(Predicted)
• PKA: 8.82±0.23(Predicted)
• CAS DataBase Reference: 2-BroMo-5-hydroxy-N-(4-hydroxyphenethyl)-4-Methoxy-N-MethylbenzaMide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BroMo-5-hydroxy-N-(4-hydroxyphenethyl)-4-Methoxy-N-MethylbenzaMide(24958-44-9)
• EPA Substance Registry System: 2-BroMo-5-hydroxy-N-(4-hydroxyphenethyl)-4-Methoxy-N-MethylbenzaMide(24958-44-9)

Safety Data

• Hazardous Substances Data: 24958-44-9(Hazardous Substances Data)

Usage

General Description

2-Bromo-5-hydroxy-N-(4-hydroxyphenethyl)-4-methoxy-N-methylbenzamide is a chemical compound that belongs to the class of benzamide derivatives. It is a brominated phenethylamine derivative with a methoxy group and a hydroxy group attached to the benzene ring. 2-BroMo-5-hydroxy-N-(4-hydroxyphenethyl)-4-Methoxy-N-MethylbenzaMide has potential biological activity and has been studied for its potential pharmacological properties. It may have relevance in the development of new pharmaceutical drugs or as a research tool in the study of specific biological processes. Its precise mechanism of action and specific applications are areas of ongoing research and investigation.

Upstream product

• 61186-07-0 N-methyl-N-(2-[4-hydroxyphenyl]ethyl)amine hydrobromide 
• 370-98-9 N-methyltyramine 
• 24958-43-8 5-benzyloxy-N-[2-(4-benzyloxy-phenyl)-ethyl]-2-bromo-4-methoxy-N-methylbenzamide 
• 72785-25-2 2-(4-methoxybenzyloxyphenyl)-ethyl-N-methylamine 
• 125145-48-4 2-bromo-4-methoxy-5-(4-methoxybenzyloxy)-benzylacetate 
• 72785-28-5 4-methoxy-5-(4-methoxybenzyloxy)-benzyl acetate 
• 125145-49-5 2-bromo-4-methoxy-5-(4-methoxybenzyloxy)-benzyl alcohol 
• 72785-26-3 2-bromo-4-methoxy-5-(4-methoxybenzyloxy)-benzoic acid 
• 125145-47-3 4-methoxy-5-(4-methoxybenzyloxy)benzyl alcohol 
• 72785-29-6 4-methoxy-3-((4-methoxybenzyl)oxy)benzaldehyde 
• 125145-46-2 4-(4-methoxybenzyloxy)-phenyl-N-methylthioacetamide 
• 125145-45-1 4-(4-methoxybenzyloxy)-phenyl-N-methylacetamide 
• 1026005-61-7 [4-(4-Methoxy-benzyloxy)-phenyl]-acetyl chloride 
• 76968-91-7 4-((4-methoxy)benzyloxy)phenylacetic acid 

Downstream Products

• 357-70-0 galanthamine 
• 125145-52-0 C₁₇H₁₈BrNO₄ 
• 1668-85-5 (-)-epigalanthamine 
• 23173-11-7 rac-8-bromo-6-methoxy-10-methyl-galantham-1-ene-3,9-dione 
• 261961-56-2 4a,5,9,10,11,12-hexahydro-1-bromo-3-methoxy-11-methyl-6H-12-oxobenzofuro[3a,3,2,-ef][2]-benzazepin-6-one 
• 24997-76-0 C₁₇H₁₆BrNO₄ 

Relevant articles and documents

Process for making galantamine

A novel process for the preparation of N-methyl-N-(2-[4-hydroxyphenyl]ethyl)-5-hydroxy-4-methoxy benzene carboxamide, which is useful as an intermediate in the synthesis of (?)-galantamine, comprises the reaction of a 5-hydroxy-4-methoxy benzoic acid derivative with N-methyl-N-(2-[4-hydroxyphenyl]ethyl)amine.

Syntheses and Preparations of Narwedine and Related Novel Compounds

The present invention relates to a process for preparing racemic narwedine (which can be can be kinetically resolved) to yield (?)-narwedine and which is the biogenic precursor of (?)-galanthamine) and the use thereof as a starting material for producing (?)-galanthamine. The invention further includes processes for preparing (?)-galanthamine and (?)-galanthamine hydrobromide, as well as related novel compounds.

Preparation of (-)-galantamine hydrobromide

A process for preparing (?)-galantamine hydrobromide.