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(3-Bromo-4-iodo-phenyl)-Methanol is a chemical compound characterized by a phenyl ring with both bromine and iodine atoms substituted on it, along with a methanol group attached to the phenyl ring. (3-BroMo-4-iodo-phenyl)-Methanol is known for its versatility in organic synthesis and pharmaceutical research, serving as a fundamental building block for creating a diverse array of molecules and pharmaceutical compounds. The combination of bromine and iodine atoms in the molecule renders it a valuable reagent for a broad spectrum of chemical reactions. Its application in medicinal chemistry is particularly noteworthy due to the potential biological activities linked to the bromo and iodo substituents. Furthermore, the presence of the methanol group facilitates additional modification and functionalization, enhancing its utility in the realms of chemical and pharmaceutical research.

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  • 249647-26-5 Structure
  • Basic information

    1. Product Name: (3-BroMo-4-iodo-phenyl)-Methanol
    2. Synonyms: (3-BroMo-4-iodo-phenyl)-Methanol;3-bromo-4-iodobenzenemethanol
    3. CAS NO:249647-26-5
    4. Molecular Formula: C7H6BrIO
    5. Molecular Weight: 312.93041
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 249647-26-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (3-BroMo-4-iodo-phenyl)-Methanol(CAS DataBase Reference)
    10. NIST Chemistry Reference: (3-BroMo-4-iodo-phenyl)-Methanol(249647-26-5)
    11. EPA Substance Registry System: (3-BroMo-4-iodo-phenyl)-Methanol(249647-26-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 249647-26-5(Hazardous Substances Data)

249647-26-5 Usage

Uses

Used in Organic Synthesis:
(3-Bromo-4-iodo-phenyl)-Methanol is used as a key intermediate in the synthesis of various organic molecules. Its unique structure allows for a wide range of chemical reactions, making it a versatile component in the creation of complex organic compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (3-Bromo-4-iodo-phenyl)-Methanol is utilized as a building block for the development of new pharmaceutical compounds. The presence of bromine and iodine atoms in the molecule contributes to its potential biological activities, which can be harnessed for the creation of novel drugs with specific therapeutic properties.
Used in Medicinal Chemistry:
(3-Bromo-4-iodo-phenyl)-Methanol is employed as a valuable tool in medicinal chemistry, where its unique structural features and potential biological activities are explored for the design and synthesis of new therapeutic agents. (3-BroMo-4-iodo-phenyl)-Methanol's ability to undergo further modification and functionalization makes it an attractive candidate for the development of targeted drug molecules.
Used in Chemical Research:
(3-Bromo-4-iodo-phenyl)-Methanol is also used in chemical research to study the reactivity and properties of bromine and iodine atoms in different chemical environments. This knowledge can be applied to understand and predict the behavior of similar compounds in various chemical reactions and processes.

Check Digit Verification of cas no

The CAS Registry Mumber 249647-26-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,4,9,6,4 and 7 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 249647-26:
(8*2)+(7*4)+(6*9)+(5*6)+(4*4)+(3*7)+(2*2)+(1*6)=175
175 % 10 = 5
So 249647-26-5 is a valid CAS Registry Number.

249647-26-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name (3-bromo-4-iodophenyl)methanol

1.2 Other means of identification

Product number -
Other names 3-bromo-4-iodobenzyl alcohol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:249647-26-5 SDS

249647-26-5Relevant articles and documents

The Discovery and Structure-Activity Evaluation of (+)-Floyocidin B and Synthetic Analogs

Bauer, Armin,Becker, Jonathan,Hammann, Peter,Kleiner, Yolanda,Kurz, Michael,Marner, Michael,Mihajlovic, Sanja,Vilcinskas, Andreas,Zubeil, Florian,K?nig, Henrik F.,Kl?dtke, Jannike,P?verlein, Christoph,Sch?berle, Till F.,Schuler, S?ren M. M.

supporting information, (2021/11/18)

Tuberculosis represents one of the ten most common courses of death worldwide and the emergence of multidrug-resistant M. tuberculosis makes the discovery of novel anti-tuberculosis active structures an urgent priority. Here, we show that (+)-floyocidin B representing the first example of a novel dihydroisoquinoline class of fungus-derived natural products, displays promising antitubercular hit properties. (+)-Floyocidin B was identified by activity-guided extract screening and its structure was unambiguously determined by total synthesis. The absolute configuration was deduced from a key synthesis intermediate by single crystal X-ray diffraction analysis. A hit series was generated by the isolation of further natural congeners and the synthesis of analogs of (+)-floyocidin B. Extensive biological and physicochemical profiling of this series revealed first structure-activity relationships and set the basis for further optimization and development of this novel antitubercular scaffold.

SPIROCYCLIC ISOXAZOLINE DERIVATIVES AS ANTIPARASITIC AGENTS

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, (2013/03/26)

The invention recites spirocyclic isoxazoline derivatives of Formula (V.1), Formula (V.2), Formula (V.1.1), and Formula (1) stereoisomers thereof, veterinarily acceptable salts thereof, compositions thereof, processes for making, and their use as a parasi

ISOXAZOLINE DERIVATIVES AS ANTIPARASITIC AGENTS

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, (2013/03/26)

This invention recites isoxazoline substituted azetidine derivatives of Formula (1) stereoisomers thereof, veterinarily acceptable salts thereof, compositions thereof, and their use as a parasiticide in mammals and birds. R1a, R1b, R1c, R2, R3, R4, R6, and n are as described herein.

Discovery of potent and selective SH2 inhibitors of the tyrosine kinase ZAP-70

Vu, Chi B.,Corpuz, Evelyn G.,Merry, Taylor J.,Pradeepan, Selvaluxmi G.,Bartlett, Catherine,Bohacek, Regine S.,Botfield, Martyn C.,Eyermann, Charles J.,Lynch, Berkley A.,MacNeil, Ian A.,Ram, Mary K.,Van Schravendijk, Marie Rose,Violette, Shelia,Sawyer, Tomi K.

, p. 4088 - 4098 (2007/10/03)

A series of 1,2,4-oxadiazole analogues has been shown to be potent and selective SH2 inhibitors of the tyrosine kinase ZAP-70, a potential therapeutic target for immune suppression. These compounds typically are 200- 400-fold more potent than the native,

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