106896-49-5

Basic information

• Product Name: Methyl 4-amino-3-bromobenzoate
• Synonyms: METHYL 4-AMINO-3-BROMOBENZOATE;4-AMINO-3-BROMO-BENZOIC ACID METHYL ESTER;Methyl 4-amino-3-bromobenzoate 98%;Methyl 4-amino-3-bromobenzoate, GC 98%;BENZOIC ACID, 4-AMINO-3-BROMO-, METHYL ESTER;Methyl 4-amino-3-bromobenzoate,98%;4-aMino-3-broMobenzoate;2-Bromo-4-(methoxycarbonyl)aniline
• CAS NO: 106896-49-5
• Molecular Formula: C₈H₈BrNO₂
• Molecular Weight: 230.06
• Product Categories: Aromatic Esters;pharmacetical;Acids & Esters;Anilines, Amides & Amines;Bromine Compounds;C8 to C9;Carbonyl Compounds;Esters
• Mol File: 106896-49-5.mol
• Article Data: 16

Chemical Properties

• Melting Point: 105-109 °C
• Boiling Point: 334.2 °C at 760 mmHg
• Flash Point: 155.9 °C
• Appearance: Brown/Crystalline Powder
• Density: 1.6270 (rough estimate)
• Vapor Pressure: 0.00013mmHg at 25°C
• Refractive Index: 1.6120 (estimate)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 0.41±0.10(Predicted)
• CAS DataBase Reference: Methyl 4-amino-3-bromobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 4-amino-3-bromobenzoate(106896-49-5)
• EPA Substance Registry System: Methyl 4-amino-3-bromobenzoate(106896-49-5)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 22-36-36/37/38
• Safety Statements: 26-36/37-37/39
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• Hazardous Substances Data: 106896-49-5(Hazardous Substances Data)

Usage

Chemical Properties

brown crystalline powder

InChI:InChI=1/C8H8BrNO2/c1-12-8(11)5-2-3-7(10)6(9)4-5/h2-4H,10H2,1H3

Upstream product

• 67-56-1 methanol 
• 150-13-0 4-amino-benzoic acid 
• 6311-37-1 4-amino-3-bromo-benzoic acid 
• 619-45-4 4-methoxycarbonyl aniline 
• 124-41-4 sodium methylate 

Downstream Products

• 1032373-57-1 4-amino-3-naphthalen-2-ylbenzoic acid methyl ester 
• 1402939-11-0 (Z)-methyl 3-bromo-4-(methoxy(phenyl)methyleneamino)benzoate 
• 1402939-25-6 methyl 4-oxo-2-phenyl-3-p-tolyl-3,4-dihydroquinazoline-6-carboxylate 
• 594839-88-0 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid 
• 126759-30-6 3-bromo-4-nitrobenzoate methyl ester 

Relevant articles and documents

A Practical Procedure for Regioselective Bromination of Anilines

A highly practical procedure for the preparation of bromoanilines by using copper-catalyzed oxidative bromination has been developed. Treatment of free anilines with readily available NaBr and Na 2S 2O 8in the presence of a catalytic amount of CuSO 4·5H 2O enabled regioselective bromination.

Synthesis and biological evaluation of an antibacterial azaborine retinoid isostere

Our continued synthetic interest in this class of retinoids, CD437 and its analogs, against methicillin-resistant Staphylococcus aureus (MRSA) has brought us to explore further isosteric substitutions within the scaffold. Although our previous findings ha

NEW CLASS OF DNA GYRASE AND/OR TOPOISOMERASE IV INHIBITORS WITH ACTIVITY AGAINST GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA

The present invention relates to compounds having a structure of general formula (I), processes for their preparation, pharmaceutical compositions containing them as the active ingredient, to their use as medicaments and to their use in the manufacture of medicaments for use in the treatment of bacterial infections in humans and warm-blooded animals.