25125-04-6

Basic information

• Product Name: 2-ACETYL-4-NITRO-1,3-INDANEDIONE
• Synonyms: RARECHEM AR PA 0048;2-ACETYL-4-NITRO-1,3-INDANEDIONE;2-ACETYL-4-NITRO-1H-INDENE-1,3(2H)-DIONE;2-ACETYL-4-NITROINDAN-1,3-DIONE;2-ACETYL-4-NITROINDANE-1,3-DIONE;2-Acetyl-4-nitroindane-1;2-Acetyl-4-nitro-1H-indene-1,3(2H)-dione, 2-Acetyl-2,3-dihydro-4-nitro-1,3-dioxo-1H-indene
• CAS NO: 25125-04-6
• Molecular Formula: C₁₁H₇NO₅
• Molecular Weight: 233.18
• Product Categories: Indane/Indanone and Derivatives;Building Blocks;C11 to C12;Carbonyl Compounds;Chemical Synthesis;Ketones;Organic Building Blocks
• Mol File: 25125-04-6.mol

Chemical Properties

• Melting Point: 145-148 °C(lit.)
• Boiling Point: 474.5°Cat760mmHg
• Flash Point: 252.5°C
• Appearance: /
• Density: 1.508g/cm³
• Vapor Pressure: 3.61E-09mmHg at 25°C
• Refractive Index: 1.621
• CAS DataBase Reference: 2-ACETYL-4-NITRO-1,3-INDANEDIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ACETYL-4-NITRO-1,3-INDANEDIONE(25125-04-6)
• EPA Substance Registry System: 2-ACETYL-4-NITRO-1,3-INDANEDIONE(25125-04-6)

Safety Data

• Hazard Codes: Xi
• Safety Statements: S24/25:Avoid contact with skin and eyes.
• WGK Germany: 3
• Hazardous Substances Data: 25125-04-6(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
2-ACETYL-4-NITRO-1,3-INDANEDIONE is used as a reagent in organic synthesis for the production of various organic compounds, including pharmaceuticals and agrochemicals. Its unique structure and reactivity make it a valuable component in the synthesis of complex molecules.
Used in Coordination Chemistry:
2-ACETYL-4-NITRO-1,3-INDANEDIONE is used as a ligand in coordination chemistry, where it forms coordination complexes with metal ions. These complexes have potential applications in various fields, such as catalysis and materials science.
Used in Dye and Pigment Production:
2-ACETYL-4-NITRO-1,3-INDANEDIONE is used as a precursor in the production of dyes, pigments, and perfumes. Its ability to form colored compounds makes it a useful starting material for the synthesis of various dyes and pigments.
Used in Materials Science:
2-ACETYL-4-NITRO-1,3-INDANEDIONE has potential applications in the field of materials science, such as in the development of advanced polymers and coatings. Its unique properties can contribute to the creation of new materials with improved performance characteristics.
Used in Energetic Materials:
Due to its nitro group, 2-ACETYL-4-NITRO-1,3-INDANEDIONE is a potential precursor for the synthesis of energetic materials. These materials have applications in various fields, such as propellants, explosives, and pyrotechnics.

InChI:InChI=1/C11H7NO5/c1-5(13)8-10(14)6-3-2-4-7(12(16)17)9(6)11(8)15/h2-4,8H,1H3

Upstream product

• 603-11-2 3-nitrophthalic acid 
• 123-54-6 acetylacetone 
• 110-89-4 piperidine 
• 641-70-3 3-nitrophthalic acid anhydride 

Downstream Products

• 479251-60-0 3-methyl-8-aminoindeno[1,2-c]pyrazol-4-one 

Relevant articles and documents

Synthesis and evaluation of indenopyrazoles as cyclin-dependent kinase inhibitors. 3. Structure activity relationships at C3

The identification of indeno[1,2-c]pyrazol-4-ones as inhibitors of cyclin-dependent kinases (CDKs) has led to the discovery of a series of novel and potent compounds. Herein, we report the effects of substitutions at C3 of the indeno[1,2-c]pyrazol-4-one core with alkyls, heterocycles, and substituted phenyls. Substitutions at the para position of the phenyl ring at C3 were generally well-tolerated; however, larger groups were generally inactive. For alkyls directly attached to C3, longer chain substituents were not tolerated; however, shorter alkyl groups and cyclic alkyls were acceptable. In general, the heterocycles at C3 gave the most potent analogues. One such heterocycle, 24j, was examined in detail and was determined to have a biological profile consistent with CDK inhibition. An X-ray crystal structure of one of the alkyl compounds, 13q, complexed with CDK2 was determined and showed the inhibitor residing in the adenosine 5′-triphosphate pocket of the enzyme.

Protected aminosugars

The invention provides amine-protecting groups for use in solution phase or solid-phase oligosaccharide synthesis, in which a 2-substituted 1,3-dioxo compound is used to protect one or more primary amine groups of an aminosugar or gylycosylamine. The inve

Herbicidal sulfonamides

Benzenesulfonamide compounds such as N-[(4,6-dimethoxy-1,3,5-triazin-2-yl)aminocarbonyl]-1,4-dihydro-3-methyl-4-oxo-1-phenyl-indeno[1,2-C]-pyrazole-5-sulfonamide and N-[(4-methoxy-6-methyl-pyrimidin-2-yl)aminocarbonyl]-1,4-dihydro-3-methyl-4-oxo-1-phenyl-indeno[1,2-C]pyrazole-5-sulfonamide, agricultural compositions containing them, and their herbicidal utility are disclosed.